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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Laryngeal Squamous Cell Carcinoma

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma NCT03556228Phase 1, Phase 215 sites📍 Santa Rosa📍 Hartford📍 Washington D.C. VM Oncology, LLC · Tests: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg) Window Trial of Fluorescently Labeled Panitumumab (Panitumumab-IRDye800) in Head and Neck Cancer NCT06819228Phase 11 site📍 Nashville Vanderbilt-Ingram Cancer Center · Tests: Panitumumab IRDye 800 Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: SX-682, DTX TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites📍 Atlanta📍 Atlanta Emory University · Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Res… FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC NCT06788990Phase 2, Phase 3231 sites📍 Birmingham📍 Phoenix📍 La Jolla Bicara Therapeutics · Tests: Ficerafusp alfa, Pembrolizumab (KEYTRUDA®), Placebo Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Advanced Head and Neck Cancer Who Cannot Receive Cisplatin NCT07441681Phase 3150 sites📍 Birmingham📍 Anaheim📍 Baldwin Park NRG Oncology · Tests: Biospecimen Collection, Carboplatin, Cetuximab, Computed Tomography, Intensity-Modulated Radiation Therapy Intraoral Hypothermia Device for Preserving Taste During Radiation NCT06579248EARLY Phase 11 site📍 Detroit Henry Ford Health System · Tests: Intraoral Device Thermotherapy for Head and Neck Cancer Patients NCT07690618Phase 11 site📍 Rotterdam Erasmus Medical Center · Tests: Thermotherapy, Radiotherapy, Concurrent chemoradiation Combining Immunotherapy Salvage Surgery & IORT Tx Persistent/Recurrent Head & Neck Cancer NCT04754321Phase 11 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: External Beam Radiation Therapy, Intraoperative Radiation Therapy, Pembrolizumab, Quality-of-Life Assessment, Salvage S… VoiceS: Voice Quality After Transoral CO2-Laser Surgery Versus Single Vocal Cord Irradiation for Larynx Cancer NCT04057209NA4 sites📍 Paris📍 Mumbai📍 Bern Olgun Elicin · Tests: Single Vocal Cord Irradiation (SVCI), Arm A: Transoral CO2-Laser Microsurgical Cordectomy (TLM) Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome NCT06380686n/a2 sites📍 Essen📍 Hanover AIO-Studien-gGmbH · Tests: data collection Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery NCT02734537Phase 2679 sites📍 Birmingham📍 Anchorage📍 Anchorage ECOG-ACRIN Cancer Research Group · Tests: Cisplatin, Intensity-Modulated Radiation Therapy, Laboratory Biomarker Analysis High-Resolution PET-CT Imaging for Surgical Margin Visualization NCT06915454NA1 site📍 Nashville Vanderbilt-Ingram Cancer Center · Tests: Intra-op PET/CT Specimen Scanner Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or Radiation NCT06662058NA1 site📍 Atlanta Emory University · Tests: Audiometric Test, Audiometric Test, Audiometric Test, Interview Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck Cancer NCT06914999EARLY Phase 11 site📍 Atlanta Emory University · Tests: Computed Tomography, Fludeoxyglucose F-18, Intensity-Modulated Proton Therapy, Intensity-Modulated Radiation Therapy, P… Window of Opportunity in Preserving Laryngeal Function Trial NCT07423078Phase 21 site📍 Pittsburgh Matthew Spector · Tests: Toripalimab, Carboplatin, Cisplatin, Paclitaxel, Radiation Therapy RAPA-201 Therapy of Solid Tumors NCT05144698Phase 1, Phase 21 site📍 Hackensack Rapa Therapeutics LLC · Tests: RAPA-201 Rapamycin Resistant T Cells, Chemotherapy Prior to RAPA-201 Therapy, Pembrolizumab (PD-1 Blocking Antibody) A Study of Decreasing Radiation Therapy and Chemotherapy in People With Head and Neck Cancer NCT05544136Phase 26 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: 18F-FMISO PET/CT scan, Chemoradiation therapy, Carboplatin Intralesional Chemotherapy (IC): Cisplatin + Epinephrine NCT07392580Phase 21 site📍 Miami University of Miami · Tests: Cisplatin, Epinephrine injection, Laryngeal Biopsy, Endoscopic Surgery Testing Whether Cemiplimab (REGN2810) Plus CDX-1140 Given Prior to Surgery Are Better Than Cemiplimab (REGN2810) Alone in Patients With Stage III-IV Head and Neck Cancer NCT06980038Phase 212 sites📍 Irvine📍 Los Angeles📍 Los Angeles National Cancer Institute (NCI) · Tests: Anti-CD40 Agonist Monoclonal Antibody CDX-1140, Biopsy Procedure, Biospecimen Collection, Cemiplimab, Computed Tomograp… Compartmentalized Postoperative Radiotherapy in Head and Neck Cancer NCT07058805Phase 23 sites📍 Basel📍 Bern📍 Zurich Olgun Elicin · Tests: Compartmentalized Postoperative Radiotherapy Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant Therapy NCT05793151NA4 sites📍 St Louis📍 Durham📍 Charleston Medical University of South Carolina · Tests: ENDURE Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment NCT06589804Phase 3202 sites📍 Little Rock📍 Marysville📍 Palo Alto National Cancer Institute (NCI) · Tests: Biospecimen Collection, Cetuximab, Computed Tomography, Magnetic Resonance Imaging, Pembrolizumab Tissue Sample Collection From Patients With Head and Neck Cancer and From Healthy Participants NCT00898638n/a4 sites📍 Nashville📍 Nashville📍 Nashville Vanderbilt University Medical Center · Tests: biologic sample preservation procedure, medical chart review Afatinib in Patients With Fanconi Anemia (FA) and Advanced Head and Neck Squamous Cell Carcinoma (HNSCC) NCT06648096Phase 1, Phase 22 sites📍 Hanover📍 Barcelona Fundació Institut de Recerca de l'Hospital de la Santa Creu… · Tests: Afatinib SBRT Followed by Chemoimmunotherapy of Toripalimab Plus Docetaxel and Cisplatin for Larynx Preservation in Patients with Locally Regionally Advanced Squamous Cell Carcinoma of the Larynx and Hypopharynx NCT06611137Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: SBRT+Toripalimab Plus Docetaxel and Cisplatin Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer NCT06532279Phase 2153 sites📍 Gilbert📍 Peoria📍 Phoenix NRG Oncology · Tests: Best Practice, Biospecimen Collection, Cisplatin, Computed Tomography, Image Guided Radiation Therapy Proactive Risk-based Optimization & Notifications for Treatment & Outcomes in Head & Neck Cancer NCT07180901NA1 site📍 Montreal Centre hospitalier de l'Université de Montréal (CHUM) · Tests: Proactive Risk-Based Optimization and Notifications for Treatment and Outcomes (PRONTO) 5-Fluorouracil Response and Optimization STudy (The FROST Trial) NCT07419464Phase 21 site📍 St Louis Washington University School of Medicine · Tests: 5-Fluorouracil European Larynx Organ Preservation Study (ELOS) [MK-3475-C44] NCT06137378Phase 29 sites📍 Mannheim📍 Ulm📍 München University of Leipzig · Tests: KEYTRUDA®
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