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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Locally Advanced Colon Cancer

Comparing Efficacy and Safety of Enlituoยฎ Versus Erbituxยฎ Plus FOLFOX in Locally Advanced/Metastatic Colorectal Cancer With RAS/BRAF Wild-type and MSS/pMMR Status. NCT07595276Phase 31 site๐Ÿ“ Guangzhou Taizhou Mabtech Pharmaceutical Co.,Ltd ยท Tests: Enlituoยฎ, Erbituxยฎ A Dose-Expansion Trial of Intravenous HNF4ฮฑ srRNA for Unresectable or Metastatic Colorectal Cancer NCT07050394EARLY Phase 11 site๐Ÿ“ Shanghai Shanghai Changzheng Hospital ยท Tests: CD-GA-102 A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors NCT06440005Phase 17 sites๐Ÿ“ Los Angeles๐Ÿ“ Sarasota๐Ÿ“ St Louis Angiex, Inc. ยท Tests: AGX101 A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites๐Ÿ“ Aurora๐Ÿ“ Lake Mary๐Ÿ“ Lebanon 7 Hills Pharma, LLC ยท Tests: Alintegimod, Ipilimumab, Nivolumab A Study of SI-B003, BL-B01D1+SI-B003 and BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Esophageal Cancer, Gastric Cancer, Colorectal Cancer and Other Gastrointestinal Tumors NCT06008054Phase 21 site๐Ÿ“ Beijing Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: SI-B003, BL-B01D1, PD-1 Monoclonal Antibody Toripalimab Plus Celecoxib for dMMR/MSI-H Locally Advanced Colorectal Cancer NCT06903858Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Toripalimab plus celecoxib, Non-operative management, Curative-intent surgery Tafolecimab Combined With Chemoimmunotherapy as Neoadjuvant Treatment for pMMR/MSS Locally Advanced Colon Cancer NCT07840677Phase 21 site๐Ÿ“ Chongqing Daping Hospital and the Research Institute of Surgery of thโ€ฆ ยท Tests: Tafolecimab, Sintilimab A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumor and Other Solid Tumor NCT05262491Phase 16 sites๐Ÿ“ Beijing๐Ÿ“ Nanchang๐Ÿ“ Jinan Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1 EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ยฑ Pembrolizumab in Advanced Solid Tumors NCT07410676Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: EBNK-001 + IL-15 + Pembrolizumab Radiotherapy + Systemic Therapy as Conversion Therapy for pMMR/MSS T4M0 Colon Cancer๏ผˆNeo-Color๏ผ‰ NCT06949111Phase 21 site๐Ÿ“ Shijiazhuang Hebei Medical University Fourth Hospital ยท Tests: radiotherapy, CAPOX, Capecitabine, Iparomlimab and Tuvonralimab Injection GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors NCT06265025Phase 1, Phase 24 sites๐Ÿ“ Goyang-si๐Ÿ“ Seoul๐Ÿ“ Seoul GeneMedicine Co., Ltd. ยท Tests: GM103 (Part A), GM103 (Part B), GM103 and Pembrolizumab (Part C) Perioperative Versus Postoperative CapOX Chemotherapy for Locally Advanced Colon Cancer NCT03125980Phase 31 site๐Ÿ“ Shanghai Fudan University ยท Tests: capecitabine plus oxaliplatin before and after surgery, capecitabine plus oxaliplatin after surgery Neoadjuvant Chemotherapy Plus Sequential Immune Checkpoint Inhibitor (ICI) Therapy in Locally Advanced Colon Cancer NCT06368141Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Serplulimab, Capecitabine, Oxaliplatin Study of IBI3028 in Participants With Locally Advanced, Unresectable, or Metastatic Solid Tumors NCT07589205Phase 11 site๐Ÿ“ Tianjin Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. ยท Tests: Drug: IBI3028 HDAC Inhibitor Combination With Chemoimmunotherapy in the Neoadjuvant Treatment of pMMR Locally Advanced Colon Cancer NCT06709885Phase 21 site๐Ÿ“ Chongqing Daping Hospital and the Research Institute of Surgery of thโ€ฆ ยท Tests: Chidamide + Tislelizumab + chemotherapy (CapeOX ), CapeOX A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression NCT06682793Phase 1, Phase 210 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B395, xT CDx with HLA-LOH assay AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors NCT07454642Phase 17 sites๐Ÿ“ Scottsdale๐Ÿ“ Sarasota๐Ÿ“ Chicago Avacta Life Sciences Ltd ยท Tests: AVA6103 Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC NCT06791512Phase 31 site๐Ÿ“ Guangzhou Jun Huang ยท Tests: mFOLFOX6 + Bevacizumab + PD-1 monoclonal antibody, mFOLFOX6 Circulating Tumor DNA (ctDNA) as a Predictive Biomarker for Immunotherapy in Advanced or Locally Advanced dMMR/MSI-H Colorectal Patients NCT06098560n/a2 sites๐Ÿ“ Beijing๐Ÿ“ Shanghai Geneplus-Beijing Co. Ltd. A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements NCT03093116Phase 1, Phase 2165 sites๐Ÿ“ Duarte๐Ÿ“ Glendale๐Ÿ“ La Jolla Turning Point Therapeutics, Inc. ยท Tests: Oral repotrectinib (TPX-0005) A First-in-Human Escalation and Expansion Study of Patients With Advanced Solid Tumors NCT06783569Phase 12 sites๐Ÿ“ Harbin๐Ÿ“ Shenyang JiaRay Group ยท Tests: JR8603 Cemiplimab With or Without Fianlimab to Treat Older Patients With Localized or Locally Advanced MSI-H Colorectal Cancer NCT06205836Phase 21 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: Cemiplimab, Fianlimab A Phase 1 Study of TGI-5 as Monotherapy and in Combination With Nivolumab in Subjects With Locally Advanced/Metastatic Solid Tumors NCT07376707Phase 11 site๐Ÿ“ Shanghai Hefei TG ImmunoPharma Co., Ltd. ยท Tests: TGI-5 177Lu-BetaBart in Patients With Relapsed/Refractory, Locally Advanced Inoperable, or Metastatic Solid Tumors NCT07189871Phase 1, Phase 25 sites๐Ÿ“ Dothan๐Ÿ“ Grand Rapids๐Ÿ“ Omaha Radiopharm Theranostics, Ltd ยท Tests: 177Lu-BetaBart, BetaBart + unlabeled BetaBart Neoadjuvant Chemotherapy, Anti-PD-1 Antibody and Sitagliptin for Locally Advanced pMMR CRC NCT07365592Phase 1, Phase 21 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Oxaliplatin, Capecitabine, Anti-PD-1 monoclonal antibody, Sitagliptin (DPP4 inhibitor) Remote Monitoring and Symptom Management Digital Application NCT07553572NA1 site๐Ÿ“ Boston Patrick C. Johnson, MD ยท Tests: ASSIST phone application A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors NCT07094204Phase 122 sites๐Ÿ“ Santa Monica๐Ÿ“ Atlanta๐Ÿ“ Jefferson Astellas Pharma Inc ยท Tests: ASP5834, panitumumab Trial of 5-Fluorouracil (5FU)-Based Therapy in Combination With Fruquintinib in Patients With Locally Advanced Unresectable or Metastatic Colorectal Cancer NCT07042685Phase 21 site๐Ÿ“ Houston The Methodist Hospital Research Institute ยท Tests: Fruquintinib Combined With Chemotherapy Study to Evaluate the Use of Capecitabine in Monotherapy and in Combination With Oxaliplatin in Elderly Patients as Adjuvant Chemotherapy for Locally Advanced Colorectal Cancer. NCT06888843Phase 21 site๐Ÿ“ Nizhny Novgorod Nizhny Novgorod Regional Clinical Oncology Center ยท Tests: Capecitabine, Oxaliplatin
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