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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Locally Advanced Gastric or Gastroesophageal Junction Cancer

SHR-1701 With or Without Apatinib in Combination With Chemotherapy as Neoadjuvant Therapy for Gastric Cancer NCT07464756Phase 21 site๐Ÿ“ Nanjing The First Affiliated Hospital with Nanjing Medical Universiโ€ฆ ยท Tests: SHR-1701, apatinib, S-1 & Oxaliplatin A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer. NCT06902545n/a15 sites๐Ÿ“ Goyang-si๐Ÿ“ Suwon๐Ÿ“ Suwon Astellas Pharma Korea, Inc. ยท Tests: zolbetuximab Neoadjuvant Iparomlimab and Tuvonralimab With Nab-P-SOX in Locally Advanced Gastric or Gastroesophageal Junction Cancer NCT07867392Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Iparomlimab and Tuvonralimab (QL1706), nab-P-SOX๏ผˆnab-paclitaxel, oxaliplatin, S-1๏ผ‰ A Study of Novel Agents or Combinations as Perioperative Treatment in Participants With Locally Advanced Resectable Gastroesophageal Adenocarcinoma NCT07069712Phase 270 sites๐Ÿ“ Newark๐Ÿ“ Washington D.C.๐Ÿ“ Fairway AstraZeneca ยท Tests: Sonesitatug Vedotin, Rilvegostomig, Trastuzumab Deruxtecan (T-DXd), Capecitabine, 5-Fluorouracil (5-FU) A Phase โ…ข Clinical Study of HLX22 in Combination With Trastuzumab and Chemotherapy for the Treatment of Gastroesophageal Junction and Gastric Cancer NCT06532006Phase 3208 sites๐Ÿ“ Anaheim๐Ÿ“ Los Alamitos๐Ÿ“ Greeley Shanghai Henlius Biotech ยท Tests: HLX22, Pembrolizumab, Trastuzumab, Oxaliplatin, Capecitabine Cadonilimab Combination Regimen as First-line Treatment for HER2-expressing GC/GEJ Patients NCT06650332Phase 1, Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: cadonilimab, Trastuzumab, XELOX, Disitamab Vedotin, mFOLFOX6 Perioperative Treatment of Combined Radiotherapy With SOX, Apatinib and Camrelizumab for Oesophagogastric Cancer NCT07026149Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: Apatinib+Camrelizumab+SOX, Preoperative Radiotherapy A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer NCT06901531Phase 3252 sites๐Ÿ“ Birmingham๐Ÿ“ Bakersfield๐Ÿ“ Cerritos Astellas Pharma Global Development, Inc. ยท Tests: zolbetuximab, Pembrolizumab, Capecitabine, Oxaliplatin, Folinic acid (leucovorin or local equivalent) Clinical Study of Adebrelimab Therapy in the Perioperative Treatment of Gastric Cancer or Gastroesophageal Junction Cancer NCT07522151Phase 31 site๐Ÿ“ Beijing Shanghai Shengdi Pharmaceutical Co., Ltd ยท Tests: Adebrelimab plus S-1 and oxaliplatin, Adebrelimab blank preparation plus S-1 and oxaliplatin. DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 17 sites๐Ÿ“ Denver๐Ÿ“ Grand Rapids๐Ÿ“ St Louis Duboce Biopharmaceuticals, Inc. ยท Tests: DBC-664 Chemoradiotherapy and SHR-1701 in Patients With Unresectable Gastric Cancer NCT07689851Phase 23 sites๐Ÿ“ Shenzhen๐Ÿ“ Taiyuan๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: COPOX, Radiotherapy, SHR-1701 Apatinib as the First-Line Therapy in Elderly Locally Advanced or Metastatic Gastric Cancer NCT03219593Phase 21 site๐Ÿ“ Bengbu The First Affiliated Hospital of Bengbu Medical University ยท Tests: Apatinib mesylate tablets Perioperative HLX10 (Serplulimab) With S-1+Oxaliplatin (SOX) in Locally Advanced and PD-L1-Positive Gastric or Esophagogastric Junction Adenocarcinoma NCT07699939Phase 218 sites๐Ÿ“ Chiba๐Ÿ“ Fukuoka๐Ÿ“ Gifu National Cancer Center, Japan ยท Tests: serplulimab, Placebo A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ Miami Astellas Pharma Global Development, Inc. ยท Tests: ASP546C Tislelizumab Plus FOLFOX Versus POF in the Treatment of Locally Advanced: a Multicenter, Open-label, Randomized Phase III Studyunresectable or Metastatic Gastric/Gastroesophageal Junction Adenocarcinoma NCT06793917Phase 31 site๐Ÿ“ Fuzhou Fujian Cancer Hospital ยท Tests: Tislelizumab, Oxaliplatin injection, Levo-Leucovorin, 5-fluorouracil, Paclitaxel Neoadjuvant Cadonilimab Combined With Perioperative Oxaliplatin Plus S1 for Diffuse or Mixed Type of Locally Advanced Gastric/Gastroesophageal Junction Adenocarcinoma NCT06949033Phase 34 sites๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou๐Ÿ“ Lanzhou Zuoyi Jiao ยท Tests: Neoadjuvant cadonilimab combined with perioperative SOX, Neoadjuvant placebo plus perioperative SOX A Study of ASP2138 Given by Itself or Given With Other Cancer Treatments in Adults With Stomach Cancer, Gastroesophageal Junction Cancer, or Pancreatic Cancer NCT05365581Phase 146 sites๐Ÿ“ Orange๐Ÿ“ Santa Monica๐Ÿ“ Chicago Astellas Pharma Global Development, Inc. ยท Tests: ASP2138, Pembrolizumab, Oxaliplatin, Leucovorin, Fluorouracil A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas NCT06999187Phase 110 sites๐Ÿ“ Denver๐Ÿ“ Orlando๐Ÿ“ Sarasota Dren Bio ยท Tests: DR-0202 A Study of ASP2138 Together With Chemotherapy and Pembrolizumab in Adults With Gastric Cancer NCT07673887Phase 38 sites๐Ÿ“ Saint Louis Park๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Astellas Pharma Global Development, Inc. ยท Tests: ASP2138, Pembrolizumab, Oxaliplatin, Capecitabine, Folinic acid Givastomig Combined With Nivolumab and Chemotherapy in Adults With CLDN18.2 Positive Metastatic Gastric Cancer (GIVA-2) NCT07432295Phase 26 sites๐Ÿ“ Goodyear๐Ÿ“ Duarte๐Ÿ“ Boston I-Mab Biopharma US Limited ยท Tests: Givastomig, Nivolumab, 5Fluorouracil, Leucovorin, Oxaliplatin Study of TDXd, Chemotherapy, Pembrolizumab, and Trastuzumab in First-Line Metastatic HER2-Positive Gastric or Gastroesophageal Junction Cancer NCT06731478Phase 3250 sites๐Ÿ“ New Haven๐Ÿ“ Skokie๐Ÿ“ Kansas City Daiichi Sankyo ยท Tests: Trastuzumab Deruxtecan, pembrolizumab, Trastuzumab, Chemotherapy A Study of Paclitaxel Combined With Apatinib and Adebrelimab in Gastric/Gastroesophageal Junction Adenocarcinoma NCT06415669Phase 21 site๐Ÿ“ Fuzhou The First Affiliated Hospital of Xiamen University ยท Tests: Paclitaxel for injection (albumin-bound), Adebrelimab, Apatinib mesylate LM-108 in Combination With Toripalimab Versus Paclitaxel Injection for the Treatment of Subjects With CCR8-Positive Gastric and Gastroesophageal Junction Adenocarcinoma NCT07362186Phase 31 site๐Ÿ“ Beijing LaNova Medicines Limited ยท Tests: LM-108 in combination with Toripalimab, Paclitaxel injection intravenous infusion Ramucirumab and Trifluridine/Tipiracil or Paclitaxel for the Treatment of Patients With Previously Treated Advanced Gastric or Gastroesophageal Junction Cancer NCT04660760Phase 215 sites๐Ÿ“ Birmingham๐Ÿ“ Scottsdale๐Ÿ“ Tucson Academic and Community Cancer Research United ยท Tests: Paclitaxel, Quality-of-Life Assessment, Ramucirumab, Trifluridine and Tipiracil Hydrochloride A Study of Cadonilimab Combined With Chemotherapy in People With Gastric or Gastroesophageal Junction Cancer NCT07631000Phase 27 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Cadonilimab Personalized Neoantigen Peptide-Based Vaccine in Combination With Pembrolizumab for Treatment of Advanced Solid Tumors NCT05269381Phase 1, Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Cyclophosphamide, Neoantigen Peptide Vaccine, Pembrolizumab, Sargramostim, Biospecimen Collection Clinical Study of Taurine Combined With Neoadjuvant Chemo-Immunotherapy for Treatment of Locally Advanced Gastric Cancer NCT06128252NA15 sites๐Ÿ“ Wuhan๐Ÿ“ Nanjing๐Ÿ“ Shenyang Tang-Du Hospital ยท Tests: Taurine, Serplulimab, XELOX regimen, Placebo Symbiotic-GI-16: A Study to Learn About the Study Medicine Called PF-08634404 in Combination With Chemotherapy in Gastroesophageal Cancer NCT07392892Phase 2, Phase 3102 sites๐Ÿ“ Atascadero๐Ÿ“ Burbank๐Ÿ“ Encino Pfizer ยท Tests: PF-08634404, Chemotherapy, Nivolumab Safety and Efficacy of SHR2554 Combined With Other Antitumor Therapies in Gastric or Gastro-oesophageal Junction Adenocarcinoma NCT07102901Phase 22 sites๐Ÿ“ Harbin๐Ÿ“ Zhengzhou Jiangsu HengRui Medicine Co., Ltd. ยท Tests: SHR2554 Tablets, SHR-A1811 Injection, SHR-A1904 Injection, SHR-1701 Injection M108 Plus CAPOX Versus Placebo Plus CAPOX as First-line Treatment for Claudin (CLDN) 18.2-Positive, HER2-Negative, PD-L1 CPS<5, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma. NCT06177041Phase 31 site๐Ÿ“ Beijing FutureGen Biopharmaceutical (Beijing) Co., Ltd ยท Tests: M108 monoclonal antibody, Placebo, Oxaliplatin, Capecitabine
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