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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Locally Advanced Nasopharyngeal Carcinoma

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma NCT03556228Phase 1, Phase 215 sites๐Ÿ“ Santa Rosa๐Ÿ“ Hartford๐Ÿ“ Washington D.C. VM Oncology, LLC ยท Tests: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg) Serplulimab Combined With Induction Chemotherapy and Radiotherapy in Nasopharyngeal Carcinoma NCT07177443Phase 31 site๐Ÿ“ Wuhan Union Hospital, Tongji Medical College, Huazhong Universityโ€ฆ ยท Tests: Radiotherapy, Serplulimab, Cisplatin Effect of Immunonutrients on Oral Mucositis in Nasopharyngeal Carcinoma Patients After Chemoradiotherapy NCT05892354NA20 sites๐Ÿ“ Fuzhou๐Ÿ“ Fuzhou๐Ÿ“ Guangzhou First Affiliated Hospital of Guangxi Medical University ยท Tests: Enteral immunonutrition, Standard enteral nutrition Proton vs Photon IMRT in Locally Advanced Nasopharyngeal Carcinoma: A Phase III Trial NCT07340515Phase 31 site๐Ÿ“ Jinan Man Hu ยท Tests: Intensity-Modulated Proton Therapy (IMPT), Intensity-Modulated Radiation Therapy (IMRT), Cisplatin, Toripalimab PD-1 Inhibitor Plus Chemotherapy Followed by Immediate Versus Selective Re-irradiation for Locally Advanced Recurrent NPC NCT07332247Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Selective re-irradiation, Immediate re-irradiation Nedaplatin Versus Cisplatin in Treatment for Nasopharyngeal Carcinoma NCT04437329Phase 31 site๐Ÿ“ Guangzhou Affiliated Cancer Hospital & Institute of Guangzhou Medicalโ€ฆ ยท Tests: Docetaxel, nedaplatin, fluorouracil, Docetaxel, cisplatin, fluorouracil, Nedaplatin, Cisplatin, Intensity modulated-radโ€ฆ Two-cycle and Three-cycle Induction Therapy With Modified TPF Regimen Combined and Camrelizumab for LANPC NCT06811844Phase 23 sites๐Ÿ“ Xiamen๐Ÿ“ Zhangzhou๐Ÿ“ Haikou The First Affiliated Hospital of Xiamen University ยท Tests: Two-cycle induction chemotherapy + immunotherapy, Three-cycle induction chemotherapy + immunotherapy Two Cycles VS Three Cycles Induction Chemotherapy in T1-4N2-3 Locally Advanced Nasopharyngeal Carcinoma NCT05860868Phase 31 site๐Ÿ“ Guangzhou First Affiliated Hospital, Sun Yat-Sen University ยท Tests: 2 cycles induction chemotherapy, 3 cycles induction chemotherapy Toripalimab Combined With Different Platinum-Based Induction Chemotherapy Regimens for Locally Advanced Nasopharyngeal Carcinoma NCT07362979Phase 24 sites๐Ÿ“ Dongguan๐Ÿ“ Guangzhou๐Ÿ“ Shenzhen Sun Yat-sen University ยท Tests: GP plus Toripalimab Induction chemotherapy+CCRT, TP plus Toripalimab Induction chemotherapy+CCRT, TPC plus Toripalimab โ€ฆ Modulation Therapy for Locally Advanced NPC Based on Plasma EBV DNA Level Post-ICT NCT05628922Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Toripalimab, Induction chemotherapy and concurrent chemoradiation Toripalimab, Induction Chemotherapy, Radiation Therapy With Omega-3 for Locally Advanced Nasopharyngeal Carcinoma NCT07136519Phase 23 sites๐Ÿ“ Zhanjiang๐Ÿ“ Zhanjiang๐Ÿ“ Zhanjiang Affiliated Hospital of Guangdong Medical University ยท Tests: Toripalimab, Omega-3, radiotherapy, Paclitaxel (albumin bound), Cisplatin A Study of BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors NCT06475300Phase 21 site๐Ÿ“ Guangzhou Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1, PD-1 Monoclonal Antibody, Pemetrexed Disodium GAPP Induction and Concurrent Chemoradiotherapy Followed by Toripalimab Maintenance for Nasopharyngeal Carcinoma. NCT06851247Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Toripalimab, Anlotinib, Gemcitabine, Cisplatin, radiation Becotatug Vedotin Combined With a PD-1 Inhibitor in the Treatment of Locally Advanced Recurrent Nasopharyngeal Carcinoma. NCT07781358Phase 21 site๐Ÿ“ Shanghai Hongmeng Yu ยท Tests: Becotatug Vedotin, PD-1 / PD-L1 monoclonal antibody Radiotherapy Alone Versus Concurrent Chemo-radiotherapy for Nasopharyngeal Carcincoma Patients With Undectable EBV DNA After One Cylce Neoadjuvant Chemotherpy NCT05674305Phase 31 site๐Ÿ“ Shanghai Fudan University ยท Tests: Radiotherapy, Cisplatin Envafolimab Plus Chemoradiotherapy for Locally Advanced NPC, a Prospective, Single Armed Phase II Trial. NCT05397769Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Envafolimab Plus Chemoradiotherapy A Phase II Trial Comparing Immunotherapy Versus Capecitabine Maintenance After Chemo-chemoradiotherapy for High-risk Nasopharyngeal Carcinoma NCT07392320Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: TP+PD1+CCRT, PD-1 Monoclonal Antibody, Capecitabine Efficacy and Safety of TPC Induction Chemotherapy Combined With Nimotuzumab and Toripalimab "Immune Sandwich" Regimen Versus Full-Course Immunotherapy for Locally Advanced Nasopharyngeal Carcinoma NCT07706985Phase 31 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Toripalimab combined with Nimotuzumab, Nimotuzumab AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001) NCT07038343Phase 1, Phase 227 sites๐Ÿ“ Gilbert๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Avenzo Therapeutics, Inc. ยท Tests: AVZO-1418, Combination Agent 1, Combination Agent 2 Iparomlimab/Tuvorlimab (QL1706) and Modified TPF Regimen for Induction Therapy in LANPC NCT07085234Phase 21 site๐Ÿ“ Xiamen The First Affiliated Hospital of Xiamen University ยท Tests: Iparomlimab/Tuvorlimab(QL-1706) and modified TPF regimen Envafolimab Combined With Chemoradiotherapy and Recombinant Human Endostatin for LA-NPC. NCT06059261Phase 21 site๐Ÿ“ Chongqing Chongqing University Cancer Hospital ยท Tests: Envafolimab and recombinant human endostatin combined with chemoradiotherapy Reduced-dose Versus Conventional-dose Intensity-modulated Radiation Therapy for Locally Advanced Nasopharyngeal Carcinoma With Remission After Induction Chemotherapy and Immunotherapy NCT07328841Phase 312 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Ming-Yuan Chen ยท Tests: Full course of PD-1blockades, Cisplatin-based induction chemotherapy, Standard-dose radiotherapy, Reduced-dose radiotheโ€ฆ A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors NCT05592626Phase 1, Phase 219 sites๐Ÿ“ Sacramento๐Ÿ“ Celebration๐Ÿ“ Miami Marengo Therapeutics, Inc. ยท Tests: STAR0602, Irinotecan (Camptosar), Docetaxel (Taxotere) The Prognostic Value of the Degree of Pathological Response of Induction Chemotherapy for NPC NCT06182657n/a1 site๐Ÿ“ Nanchang Jiangxi Provincial Cancer Hospital A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma and Other Solid Tumors NCT05956587Phase 216 sites๐Ÿ“ Chongqing๐Ÿ“ Fuzhou๐Ÿ“ Guangzhou Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1, SI-B003 Becotatug Vedotin for LA-NPC With a Suboptimal Response to Induction Chemotherapy Combined With Immunotherapy NCT07496190Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Becotatug vedotin, Becotatug vedotin A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Solid Tumor NCT05194982Phase 18 sites๐Ÿ“ Chongqing๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1 Nituzumab (Taixinsheng ยฎ๏ผ‰ A Prospective, Randomized, Double-blind, Placebo-controlled, Multicenter Phase II Clinical Study on the Efficacy and Safety of Combined Induction Chemotherapy for Locally Advanced Nasopharyngeal Carcinomatreatment of Locally Advanced Nasopharyngeal Carcinoma NCT05508347Phase 21 site๐Ÿ“ Chengdu Sichuan Cancer Hospital and Research Institute ยท Tests: Nituzumab/placebo Intensified Treatments for Patients With Locally Advanced Nasopharyngeal Carcinoma With Detectable EBV DNA After One Cycle GP Regime Neoadjuvant Chemotherapy NCT05772208Phase 31 site๐Ÿ“ Shanghai Fudan University ยท Tests: Camrelizumab, Nimotuzumab, neoadjuvant chemotherapy and CCRT Concurrent Chemotherapy for Recurrent T3/T4 Nasopharyngeal Carcinoma NCT04136886Phase 31 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Cisplatin, IMRT
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