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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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20 recruiting trials

for Locally Advanced Oral Squamous Cell Carcinoma

VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma NCT03556228Phase 1, Phase 215 sites๐Ÿ“ Santa Rosa๐Ÿ“ Hartford๐Ÿ“ Washington D.C. VM Oncology, LLC ยท Tests: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg) Prospective Cohort Study on Oral Microbiome Changes in Patients With Locally Advanced Oral Squamous Cell Carcinoma Following Neoadjuvant Chemoimmunotherapy NCT07111455n/a1 site๐Ÿ“ Guangzhou Zhujiang Hospital Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Advanced Head and Neck Cancer Who Cannot Receive Cisplatin NCT07441681Phase 3150 sites๐Ÿ“ Birmingham๐Ÿ“ Anaheim๐Ÿ“ Baldwin Park NRG Oncology ยท Tests: Biospecimen Collection, Carboplatin, Cetuximab, Computed Tomography, Intensity-Modulated Radiation Therapy Thermotherapy for Head and Neck Cancer Patients NCT07690618Phase 11 site๐Ÿ“ Rotterdam Erasmus Medical Center ยท Tests: Thermotherapy, Radiotherapy, Concurrent chemoradiation Tirilizumab with Albumin-bound Paclitaxel and Cisplatin for Locally Advanced Resectable Oral Squamous Cell Carcinoma NCT06470217Phase 21 site๐Ÿ“ Shanghai Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaโ€ฆ ยท Tests: tirilizumab with albumin-bound paclitaxel and cisplatin, surgery d-Limonene +Radiation +PlatinumBasedChemo for Xerostomia Prevention in LocallyAdvanced HNSCC NCT04392622Phase 11 site๐Ÿ“ Stanford Stanford University ยท Tests: D-Limonene Gelcaps, Intensity modulated radiotherapy (IMRT), Cisplatin, Xerostomia questionnaire A Bidirectional Observational Clinical Study of NAIC in the Treatment of Tumor Regression Patterns in LA-OSCC and LA-OPSCC NCT07133958n/a1 site๐Ÿ“ Guangzhou Zhujiang Hospital First-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, as Monotherapy and in Combination With Anticancer Therapy in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian Cancer NCT06799065Phase 1, Phase 211 sites๐Ÿ“ Aurora๐Ÿ“ Sarasota๐Ÿ“ Detroit Accent Therapeutics ยท Tests: ATX-295, ATX-295 and bevacizumab (or biosimilar) Iparomlimab and Tuvonralimab With With Cetuximab in Resectable OSCC NCT07882888Phase 21 site๐Ÿ“ Shanghai Shanghai Ninth People's Hospital Affiliated to Shanghai Jiaโ€ฆ ยท Tests: iparomlimab and tuvonralimab combined with cetuximab Neoadjuvant Immunochemotherapy for LAOSCC NCT06258811Phase 31 site๐Ÿ“ Shanghai Lai-ping Zhong ยท Tests: albumin paclitaxel, cispatin, tislelizumab Neoadjuvant Personalized Anti-PD-1 and Anti-VEGFR Therapy in OSCC Patients NCT05069857Phase 21 site๐Ÿ“ Shanghai Shanghai Jiao Tong University School of Medicine ยท Tests: Camrelizumab (anti-PD-1 inhibitor), Apatinib (anti-VEGFR inhibitor) Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck Cancer NCT05172245Phase 118 sites๐Ÿ“ Tampa๐Ÿ“ Chicago๐Ÿ“ Fairway National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cisplatin, Computed Tomography, Ipatasertib Neoadjuvant Anti-PD-1 and TP Versus TPF on Pathological Response in OSCC NCT05125055Phase 2, Phase 31 site๐Ÿ“ Shanghai Shanghai Jiao Tong University School of Medicine ยท Tests: Toripalimab (anti-programmed death-1 inhibitor), Albumin paclitaxel, Cisplatin, Docetaxel, 5-Fluorouracil Exploratory Clinical Trial of Oral Paclitaxel Plus Radiotherapy in Patients With Locally Advanced Unresectable Esophageal Squamous Cell Carcinoma NCT07435454Phase 21 site๐Ÿ“ Nanjing Jiangsu Cancer Institute & Hospital ยท Tests: oral paclitaxel+radiotherapy Sintilimab Plus Chemotherapy as Neoadjuvant and Adjuvant Treatment for Locally Advanced Oral Squamous Cell Carcinoma NCT07371611Phase 31 site๐Ÿ“ Guangzhou Qunxing Li,MD ยท Tests: Sintilimab plus nab-paclitaxel and platinum-based chemotherapy, Radical surgery combined with radiotherapy or chemoradiโ€ฆ Neoadjuvant Treatment of Tislelizumab Combined Chemotherapy for Locally Advanced Oral Squamous Cell Carcinoma ๏ผšA Single-arm, Prospective, Phase II Trial NCT05862168Phase 21 site๐Ÿ“ Hangzhou Weijia Fang, MD ยท Tests: Tislelizumab, Albumin paclitaxel, Cisplatin, 5-Fluorouracil Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck Cancer NCT07195734Phase 2115 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Irvine National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Carboplatin, Cemiplimab, Cisplatin, Computed Tomography Association Between Tinnitus and Hearing Loss in Locally Advanced Head and Neck Cancer Treated by Radiotherapy Alone or With Chemotherapy: a Prospective and Multicenter Study NCT05946577n/a1 site๐Ÿ“ Paris Assistance Publique - Hรดpitaux de Paris Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytrudaยฎ) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist) NCT04198766Phase 1, Phase 242 sites๐Ÿ“ Duarte๐Ÿ“ Glendale๐Ÿ“ Los Angeles Inhibrx Biosciences, Inc ยท Tests: INBRX-106 - Hexavalent OX40 agonist antibody, pembrolizumab 200 mg, pembrolizumab 400 mg, Carboplatin AUC-5, Carboplatiโ€ฆ BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study NCT05136196Phase 2232 sites๐Ÿ“ Phoenix๐Ÿ“ Little Rock๐Ÿ“ Beverly Hills National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Cabozantinib S-malate, Computed Tomography, Magnetic Resonance Imaging
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