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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Locally Advanced Solid Tumor

A Phase I First-in-Human Study of GenSci128 in Patients With Solid Tumors Harboring a TP53 Y220C Mutation NCT06908434Phase 11 site📍 Shanghai Changchun GeneScience Pharmaceutical Co., Ltd. · Tests: GenSci128 tablets A Study of TY-2699a in Patients With Locally Advanced or Metastatic Solid Tumors NCT05866692Phase 12 sites📍 Beijing📍 Jinan TYK Medicines, Inc · Tests: TY-2699a VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma NCT03556228Phase 1, Phase 215 sites📍 Santa Rosa📍 Hartford📍 Washington D.C. VM Oncology, LLC · Tests: VMD-928 100 mg Tablet, VMD-928 Tablet and Pembrolizumab (200 mg) A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement NCT07359820Phase 219 sites📍 Phoenix📍 Jacksonville📍 Tampa Elevar Therapeutics · Tests: Lirafugratinib Imaging of Solid Tumors Using 18F-TRX NCT06942104Phase 11 site📍 San Francisco Rahul Aggarwal · Tests: 18F-TRX, Positron Emission Tomography (PET)/Computerized tomography (CT), Tumor Biopsy, Blood Specimen Collection Phase I Clinical Study of BL-M07D1 in Locally Advanced or Metastatic Digestive Tract Tumors and Other Solid Tumors NCT05631964Phase 11 site📍 Shanghai Sichuan Baili Pharmaceutical Co., Ltd. · Tests: BL-M07D1 Safety and Preliminary Efficacy of VIR-5525 and VIR-5525 + Pembrolizumab in Participants With Locally Advanced or Metastatic Solid Tumors NCT06960395Phase 14 sites📍 Scottsdale📍 Houston📍 Wollongong Vir Biotechnology, Inc. · Tests: VIR-5525, Pembrolizumab A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors NCT06440005Phase 17 sites📍 Los Angeles📍 Sarasota📍 St Louis Angiex, Inc. · Tests: AGX101 A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites📍 Aurora📍 Lake Mary📍 Lebanon 7 Hills Pharma, LLC · Tests: Alintegimod, Ipilimumab, Nivolumab Study of SYN818 for the Treatment of Advanced or Metastatic Solid Tumors NCT06666270Phase 12 sites📍 Zhengzhou📍 Shanghai Hangzhou SynRx Therapeutics Biomedical Technology Co., Ltd · Tests: SYN818 A Study of BL-M09D1 in Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer and Other Solid Tumors NCT07056556Phase 11 site📍 Shanghai Sichuan Baili Pharmaceutical Co., Ltd. · Tests: BL-M09D1 Study of ACR-2316 in Specific Advanced Solid Tumors NCT06667141Phase 1, Phase 215 sites📍 Phoenix📍 Beverly Hills📍 Newport Beach Acrivon Therapeutics · Tests: ACR-2316 A Study of NVL-330 in Patients With Advanced or Metastatic HER2-altered NSCLC (HEROEX-1) NCT06521554Phase 121 sites📍 Irvine📍 Sacramento📍 Stanford Nuvalent Inc. · Tests: NVL-330 A Study of BL-B16D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors NCT06493864Phase 11 site📍 Shanghai Sichuan Baili Pharmaceutical Co., Ltd. · Tests: BL-B16D1 A Study of ASP1002 in Adults for Treatment of Solid Tumors NCT05719558Phase 115 sites📍 New Haven📍 Plainville📍 Gainesville Astellas Pharma Global Development, Inc. · Tests: ASP1002, Bevacizumab, Oxaliplatin, Leucovorin, Fluorouracil A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC278 in the Treatment of Solid Tumors NCT07105215Phase 1, Phase 239 sites📍 Beijing📍 Fuzhou📍 Fuzhou RemeGen Co., Ltd. · Tests: RC278 FIH Trial of VERT-002 in Patients With Locally Advanced or Metastatic Solid Tumors With MET Alterations NCT06669117Phase 1, Phase 219 sites📍 Washington D.C.📍 Canton📍 Nashville Pierre Fabre Medicament · Tests: VERT-002 A Study of BL-ARC002 in Patients With Locally Advanced or Metastatic Solid Tumors NCT07591155Phase 11 site📍 Tianjin Sichuan Baili Pharmaceutical Co., Ltd. · Tests: BL-ARC002 A Study of Zidesamtinib (NVL-520) in Patients With Advanced NSCLC and Other Solid Tumors Harboring ROS1 Rearrangement (ARROS-1) NCT05118789Phase 1, Phase 263 sites📍 Orange📍 Palo Alto📍 Sacramento Nuvalent Inc. · Tests: Zidesamtinib (NVL-520) CR-001 in Adult Participants With Locally Advanced or Metastatic Solid Tumors NCT07335497Phase 1, Phase 234 sites📍 Birmingham📍 Los Angeles📍 Denver Crescent Biopharma, Inc. · Tests: CR-001, Paclitaxel, trifluridine and tipiracil, Pemetrexed, Carboplatin IBI3001 in Participants With Unresectable, Locally Advanced or Metastatic Solid Tumors NCT06349408Phase 127 sites📍 Los Angeles📍 East Brunswick📍 Dallas Fortvita Biologics (USA)Inc. · Tests: IBI3001 A Study of BL-B01D1 in Patients With Locally Advanced or Metastatic Gastrointestinal Tumor and Other Solid Tumor NCT05262491Phase 16 sites📍 Beijing📍 Nanchang📍 Jinan Sichuan Baili Pharmaceutical Co., Ltd. · Tests: BL-B01D1 EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors NCT07410676Phase 1, Phase 21 site📍 Beijing Essen Biotech · Tests: EBNK-001 + IL-15 + Pembrolizumab A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors NCT05970497Phase 1, Phase 215 sites📍 Los Angeles📍 Rancho Santa Margarita📍 Weston Krystal Biotech, Inc. · Tests: KB707, Opdualag, KEYTRUDA ®( Pembrolizumab) Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors NCT06975410Phase 1, Phase 24 sites📍 Seoul📍 Seoul📍 Seoul Yuhan Corporation · Tests: YH32364 SG1906 for CLDN18.2-Positive Solid Tumors NCT05857332Phase 19 sites📍 Beijing📍 Xiamen📍 Guangzhou Hangzhou Sumgen Biotech Co., Ltd. · Tests: SG1906 A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC288 in the Treatment of Solid Tumors NCT07537881Phase 1, Phase 214 sites📍 Hunan📍 Sichuan📍 Fujian RemeGen Co., Ltd. · Tests: RC288 For Injection, RC288 For Injection Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001) NCT05579366Phase 1, Phase 266 sites📍 Phoenix📍 Tucson📍 Los Angeles Genmab · Tests: Rina-S, Carboplatin, Bevacizumab, Pembrolizumab, Erythromycin Lattice Radiotherapy for Dose-Escalated Palliation of Bulky Tumors NCT06416007Phase 21 site📍 Cincinnati University of Cincinnati · Tests: Lattice therapy (LRT) GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors NCT06265025Phase 1, Phase 24 sites📍 Goyang-si📍 Seoul📍 Seoul GeneMedicine Co., Ltd. · Tests: GM103 (Part A), GM103 (Part B), GM103 and Pembrolizumab (Part C)
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