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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Locally Advanced Unresectable or Metastatic Solid Tumors

A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement NCT07359820Phase 219 sites๐Ÿ“ Phoenix๐Ÿ“ Jacksonville๐Ÿ“ Tampa Elevar Therapeutics ยท Tests: Lirafugratinib A Study to Evaluate Safety, Tolerability and Preliminary Activity of AGX101 in Participants With Advanced Solid Tumors NCT06440005Phase 17 sites๐Ÿ“ Los Angeles๐Ÿ“ Sarasota๐Ÿ“ St Louis Angiex, Inc. ยท Tests: AGX101 A Study of BL-B16D1 in Patients With Unresectable Locally Advanced or Metastatic Breast Cancer and Other Solid Tumors NCT06493864Phase 11 site๐Ÿ“ Shanghai Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B16D1 A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC278 in the Treatment of Solid Tumors NCT07105215Phase 1, Phase 239 sites๐Ÿ“ Beijing๐Ÿ“ Fuzhou๐Ÿ“ Fuzhou RemeGen Co., Ltd. ยท Tests: RC278 IBI3001 in Participants With Unresectable, Locally Advanced or Metastatic Solid Tumors NCT06349408Phase 127 sites๐Ÿ“ Los Angeles๐Ÿ“ East Brunswick๐Ÿ“ Dallas Fortvita Biologics (USA)Inc. ยท Tests: IBI3001 SG1906 for CLDN18.2-Positive Solid Tumors NCT05857332Phase 19 sites๐Ÿ“ Beijing๐Ÿ“ Xiamen๐Ÿ“ Guangzhou Hangzhou Sumgen Biotech Co., Ltd. ยท Tests: SG1906 A I/II Phase Clinical Study to Evaluate the Safety and Efficacy of RC288 in the Treatment of Solid Tumors NCT07537881Phase 1, Phase 214 sites๐Ÿ“ Hunan๐Ÿ“ Sichuan๐Ÿ“ Fujian RemeGen Co., Ltd. ยท Tests: RC288 For Injection, RC288 For Injection GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors NCT06265025Phase 1, Phase 24 sites๐Ÿ“ Goyang-si๐Ÿ“ Seoul๐Ÿ“ Seoul GeneMedicine Co., Ltd. ยท Tests: GM103 (Part A), GM103 (Part B), GM103 and Pembrolizumab (Part C) Study of IBI3028 in Participants With Locally Advanced, Unresectable, or Metastatic Solid Tumors NCT07589205Phase 11 site๐Ÿ“ Tianjin Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. ยท Tests: Drug: IBI3028 Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression NCT06682793Phase 1, Phase 210 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B395, xT CDx with HLA-LOH assay Tislelizumab (Anti-Programmed Cell Death Protein-1 (PD-1) Antibody) in MSI-H or dMMR Solid Tumors NCT03736889Phase 229 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Beijing BeiGene ยท Tests: Tislelizumab (BGB-A317) ABL103 in Combination With Pembrolizumab, With or Without Taxane in Advanced or Metastatic Solid Tumors NCT07158918Phase 1, Phase 26 sites๐Ÿ“ Cleveland๐Ÿ“ Frankston๐Ÿ“ Seongnam ABL Bio, Inc. ยท Tests: ABL103, KEYTRUDAยฎ (pembrolizumab), Taxane A Study of TAK-505 in Adults With Solid Tumors NCT07436728Phase 1, Phase 215 sites๐Ÿ“ Orange๐Ÿ“ San Diego๐Ÿ“ San Francisco Takeda ยท Tests: TAK-505 AD1208 in Subjects With Any Progressive, Locally Advanced or Metastatic Solid Tumors NCT06911333Phase 1, Phase 23 sites๐Ÿ“ Seongnam-si๐Ÿ“ Seoul๐Ÿ“ Seoul Avelos Therapeutics Inc. ยท Tests: AD1208 SSGJ-705 Plus SSGJ-612 ยฑ Chemotherapy in Advanced HER2-Expressing Solid Tumors NCT07646626Phase 21 site๐Ÿ“ Hangzhou Shenyang Sunshine Pharmaceutical Co., LTD. ยท Tests: SSGJ-705, SSGJ-612, SSGJ-705 combined with chemotherapy A Study to Find a Suitable Dose of ASP5834 in Adults With Solid Tumors NCT07094204Phase 122 sites๐Ÿ“ Santa Monica๐Ÿ“ Atlanta๐Ÿ“ Jefferson Astellas Pharma Inc ยท Tests: ASP5834, panitumumab Targeted Therapy Directed by Genetic Testing in Treating Patients With Locally Advanced or Advanced Solid Tumors, The ComboMATCH Screening Trial NCT05564377Phase 2484 sites๐Ÿ“ Birmingham๐Ÿ“ Mobile๐Ÿ“ Anchorage National Cancer Institute (NCI) ยท Tests: Alpelisib, Binimetinib, Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression NCT06051695Phase 1, Phase 212 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B694, A2B543, xT CDx with HLA-LOH Assay A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ Los Angeles๐Ÿ“ Miami Astellas Pharma Global Development, Inc. ยท Tests: ASP546C A Dose Escalation and Expansion Study of [177Lu]Lu-SN201 in Participants With Advanced Cancer NCT06184035Phase 1, Phase 22 sites๐Ÿ“ Adelaide๐Ÿ“ Melbourne Spago Nanomedical AB ยท Tests: [177Lu]Lu-SN201 A First-in-human Study of IBI354 in Subjects with Locally Advanced Unresectable or Metastatic Solid Tumors NCT05636215Phase 1, Phase 26 sites๐Ÿ“ Randwick๐Ÿ“ Sydney๐Ÿ“ Sunshine Coast Innovent Biologics (Suzhou) Co. Ltd. ยท Tests: IBI354 A Study of NEOK001, a B7-H3 and ROR1 Targeting Bispecific ADC in Participants With Select Solid Tumors NCT07612176Phase 19 sites๐Ÿ“ New York๐Ÿ“ Nashville๐Ÿ“ Austin NEOK Bio, Inc. ยท Tests: NEOK001, NEOK001 RDE Study of IBI3020 Treatment in Participants With Late-Stage Solid Tumors NCT06963281Phase 19 sites๐Ÿ“ Phoenix๐Ÿ“ Jacksonville๐Ÿ“ Rochester Fortvita Biologics (USA)Inc. ยท Tests: IBI3020 Study of JK06 in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT06667960Phase 1, Phase 214 sites๐Ÿ“ Antwerp๐Ÿ“ Brussels๐Ÿ“ Ghent Salubris Biotherapeutics Inc ยท Tests: JK06 A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors NCT07287995Phase 1, Phase 29 sites๐Ÿ“ Celebration๐Ÿ“ Hackensack๐Ÿ“ New Hyde Park Astellas Pharma Global Development, Inc. ยท Tests: ASP2998, Pembrolizumab, Enfortumab Vedotin, Carboplatin Personalized Neo-Antigen Peptide Vaccine for the Treatment of Stage IIIC-IV Melanoma, Hormone Receptor Positive HER2 Negative Metastatic Refractory Breast Cancer or Stage III-IV Non-Small Cell Lung Cancer NCT05098210Phase 11 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Neoantigen Peptide Vaccine, Nivolumab, Poly ICLC, Echocardiography Test, Multigated Acquisition Scan A Study of RC118 in Patients with Locally Advanced Unresectable or Metastatic Malignant Solid Tumors NCT05205850Phase 1, Phase 22 sites๐Ÿ“ Shanghai๐Ÿ“ Hangzhou RemeGen Co., Ltd. ยท Tests: RC118-ADC A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors NCT05592626Phase 1, Phase 219 sites๐Ÿ“ Sacramento๐Ÿ“ Celebration๐Ÿ“ Miami Marengo Therapeutics, Inc. ยท Tests: STAR0602, Irinotecan (Camptosar), Docetaxel (Taxotere) Study of IBI3005 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors NCT06418061Phase 11 site๐Ÿ“ Jinan Innovent Biologics (Suzhou) Co. Ltd. ยท Tests: IBI3005
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