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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Locally Advanced Urothelial Carcinoma

Circulating and Urine Tumor DNA Dynamics Predict Minimal Residual Disease and Recurrence Risk in Locally Advanced Upper Tract Urothelial Carcinoma NCT05595408n/a1 site๐Ÿ“ Shanghai RenJi Hospital ยท Tests: Adjuvant chemotherapy, adjuvant immunotherapy A Study of BL-B01D1 + PD-1 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma NCT06405425Phase 21 site๐Ÿ“ Shanghai Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1, PD-1 Postoperative Adjuvant Immunotherapy Combined with Radiotherapy Versus Surgery Alone in Locally Advanced UTUC NCT06598761n/a2 sites๐Ÿ“ Beijing๐Ÿ“ Beijing Peking University First Hospital ยท Tests: Immunotherapy+radiotherapy, surveillance alone EV + Toripalimab vs GC as Neoadjuvant Therapy in Locally Advanced/High-Risk MIBC NCT07647289Phase 21 site๐Ÿ“ Beijing Peking University Third Hospital ยท Tests: enfortumab vedotin (EV), Toripalimab, Gemcitabine (Chemotherapy), Cisplatin Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors NCT06975410Phase 1, Phase 24 sites๐Ÿ“ Seoul๐Ÿ“ Seoul๐Ÿ“ Seoul Yuhan Corporation ยท Tests: YH32364 Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC) NCT07241793Phase 26 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Adebrelimab, Trastuzumab Rezetecan 9MW2821 + Toripalimab vs 9MW2821 for 1st Line Locally Advanced or Metastatic Urothelial Carcinoma NCT06823427Phase 22 sites๐Ÿ“ Changsha๐Ÿ“ Nanjing Mabwell (Shanghai) Bioscience Co., Ltd. ยท Tests: 9MW2821, Toripalimab (JS001 ) Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract NCT07218380Phase 3276 sites๐Ÿ“ Tucson๐Ÿ“ Little Rock๐Ÿ“ Irvine Eli Lilly and Company ยท Tests: Vepugratinib, Placebo, EV, Pembrolizumab DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 17 sites๐Ÿ“ Denver๐Ÿ“ Grand Rapids๐Ÿ“ St Louis Duboce Biopharmaceuticals, Inc. ยท Tests: DBC-664 A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors NCT07020117Phase 114 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ Miami Aktis Oncology, Inc. ยท Tests: [225Ac]Ac-AKY-1189 (therapeutic), [64Cu]Cu-AKY-1189 (imaging) Cabozantinib in Combination With Enfortumab Vedotin for Locally Advanced or Metastatic Urothelial Cancer NCT04878029Phase 11 site๐Ÿ“ Atlanta Emory University ยท Tests: Cabozantinib S-malate, Enfortumab Vedotin, Quality-of-Life Assessment, Questionnaire Administration A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2 NCT04879329Phase 2221 sites๐Ÿ“ Gilbert๐Ÿ“ Gilbert๐Ÿ“ Anaheim Seagen, a wholly owned subsidiary of Pfizer ยท Tests: disitamab vedotin, pembrolizumab Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma and Other Solid Tumors NCT05965856Phase 21 site๐Ÿ“ Shanghai Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1, SI-B003 Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial NCT06764095Phase 41 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biospecimen Collection, Computed Tomography, Cystectomy, Enfortumab Vedotin, Local Therapy A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer NCT06524544Phase 3162 sites๐Ÿ“ Phoenix๐Ÿ“ Irvine๐Ÿ“ Orange National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Carboplatin, Cisplatin, Computed Tomography, Docetaxel Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma NCT06582017Phase 111 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Nammi Therapeutics Inc ยท Tests: QXL138AM Injection every 2 weeks by IV Infusion KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04) NCT07232602Phase 1, Phase 217 sites๐Ÿ“ San Francisco๐Ÿ“ Chicago๐Ÿ“ New York Merck Sharp & Dohme LLC ยท Tests: MK-3120, EV, Pembrolizumab, Rescue Medication Clofarabine Therapy in Locally Advanced or Metastatic Urothelial Carcinoma NCT07034053Phase 1, Phase 21 site๐Ÿ“ Vienna Ekaterina Laukhtina ยท Tests: Clofarabine Consolidative Local Therapy (CLT) in Oligo-metastatic Urothelial Carcinoma NCT07048457Phase 22 sites๐Ÿ“ New Haven๐Ÿ“ Madison Yale University ยท Tests: Radical cystectomy 9MW2821 in Combination With Toripalimab vs Standard Chemotherapy in Locally Advanced or Metastatic Urothelial Cancer NCT06592326Phase 31 site๐Ÿ“ Shanghai Mabwell (Shanghai) Bioscience Co., Ltd. ยท Tests: 9MW2821, Toripalimab, Gemcitabine, Cisplatin/Carboplatin A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas NCT06999187Phase 110 sites๐Ÿ“ Denver๐Ÿ“ Orlando๐Ÿ“ Sarasota Dren Bio ยท Tests: DR-0202 A Study of ASP2998 Given by Itself and Given With Standard Therapies in People With Solid Tumors NCT07287995Phase 1, Phase 29 sites๐Ÿ“ Celebration๐Ÿ“ Hackensack๐Ÿ“ New Hyde Park Astellas Pharma Global Development, Inc. ยท Tests: ASP2998, Pembrolizumab, Enfortumab Vedotin, Carboplatin AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001) NCT07038343Phase 1, Phase 227 sites๐Ÿ“ Gilbert๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Avenzo Therapeutics, Inc. ยท Tests: AVZO-1418, Combination Agent 1, Combination Agent 2 A Study to Evaluate 9MW2821 Versus Chemotherapy in Subjects With Previously Treated Locally Advanced or Metastatic Urothelial Cancer NCT06196736Phase 31 site๐Ÿ“ Shanghai Mabwell (Shanghai) Bioscience Co., Ltd. ยท Tests: 9MW2821, Chemotherapy Gemcitabine and Carboplatin After Progression on Enfortumab Vedotin and Pembrolizumab in Advanced/Metastatic Urothelial Carcinoma NCT07043972Phase 22 sites๐Ÿ“ Philadelphia๐Ÿ“ Philadelphia Fox Chase Cancer Center ยท Tests: Gemcitabine, Carboplatin Safety and Tolerability of TNG462 in Patients With MTAP-deleted Solid Tumors NCT05732831Phase 1, Phase 226 sites๐Ÿ“ Palo Alto๐Ÿ“ Grand Junction๐Ÿ“ Lake Mary Tango Therapeutics, Inc. ยท Tests: TNG462, Pembrolizumab Symbiotic-GU-06: A Study to Learn About PF-08634404 Alone or In Combination With Enfortumab Vedotin in Urothelial Cancer NCT07421700Phase 1, Phase 2184 sites๐Ÿ“ Fayetteville๐Ÿ“ Rogers๐Ÿ“ Springdale Pfizer ยท Tests: PF-08634404, Enfortumab Vedotin A Study of Ivonescimab in Combination With Enfortumab Vedotin vs Pembrolizumab in Combination With Enfortumab Vedotin in Metastatic Urothelial Carcinoma NCT07815665Phase 2, Phase 37 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ Washington D.C. Summit Therapeutics ยท Tests: Ivonescimab Dose 1, enfortumab vedotin (EV), Pembrolizumab, Ivonescimab Dose 2, Ivonescimab RP3D
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