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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Lung Cancer Stage IV

Pulmonary Rehabilitation in Advanced Lung Cancer Survivors NCT07104630Phase 21 site📍 Cleveland Case Comprehensive Cancer Center · Tests: Pulmonary Rehabilitation (PR), No intervention: Usual care A Study of Targeted Radiation Therapy in People With Non-Small Cell Lung Cancer (NSCLC) NCT05657873Phase 29 sites📍 Miami📍 Basking Ridge📍 Middletown Memorial Sloan Kettering Cancer Center · Tests: L-SABR, Anti-PD-(L)1 based immunotherapy, Platinum based chemotherapy Temozolomide and Atezolizumab for Subsequent Line for the Treatment of Metastatic or Recurrent Small Cell Lung Cancer NCT04919382Phase 25 sites📍 Chicago📍 Indianapolis📍 Iowa City Dwight Owen · Tests: Atezolizumab, Temozolomide Phase 3 Study of Taletrectinib vs Placebo as an Adjuvant Therapy in ROS1 Positive NSCLC (TRUST-IV) NCT07154706Phase 333 sites📍 Los Angeles📍 Orange📍 Washington D.C. Nuvation Bio Inc. · Tests: Taletrectinib, Placebo Novel INPUT Screening Tool to Improve Illness Understanding in Patients With Metastatic or Incurable Lung Cancer NCT06743308NA1 site📍 Houston M.D. Anderson Cancer Center · Tests: Best Practice, Questionnaire Administration A Study of Pembrolizumab With or Without Chemotherapy in Combination With Additional Treatments for Advanced Non-Small Cell Lung Cancer (NSCLC) (MK-3475-01G/KEYMAKER U01) NCT06731907Phase 241 sites📍 Lexington📍 Baltimore📍 Fargo Merck Sharp & Dohme LLC · Tests: Pembrolizumab, Carboplatin, Paclitaxel, Nab-paclitaxel, Pemetrexed Phase I/II Trial in ES-SCLC to Enhance Response to Atezolizumab Plus Chemotherapy With Total Body Irradiation NCT06110572Phase 1, Phase 21 site📍 Nashville Vanderbilt-Ingram Cancer Center · Tests: Carboplatin, Atezolizumab, Etoposide, Total Body Irradiation, Hypofractionated Radiation Therapy Investigating the Feasibility and Acceptability of an Innovative Interdisciplinary Supportive Care Program: Couples Coping Together Against Cancer NCT07664579n/a1 site📍 Duarte City of Hope Medical Center · Tests: Non-Interventional Study Sotorasib in Combination With Trastuzumab Deruxtecan for the Treatment of Locally Advanced and Metastatic Non-small Cell Lung Cancer With a KRAS G12C Mutation NCT07012031Phase 1, Phase 29 sites📍 Sacramento📍 Tampa📍 Tampa National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test, Magnetic Resonance Imaging Beating Lung Cancer in Ohio Protocol in Improving Survival in Patients With Stage IV Non-Small Cell Lung Cancer NCT03199651NA1 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: Best Practice, Biospecimen Collection, Biospecimen Collection, Laboratory Biomarker Analysis, Medical Chart Review Trial Comparing Systemic Therapy Alone and With Local Ablative Treatment for Stage IV NSCL Cancer Patients NCT06114108NA7 sites📍 Aarau📍 Bellinzona📍 Chur Swiss Cancer Institute · Tests: Systemic therapy alone or in combination with LAT (surgery and/or radiotherapy), Surgery, Radiotherapy Treatment for Advanced Non-small Cell Lung Cancer With Actionable Genomic Alterations After Targeted Treatment and Chemotherapy (An Expanded Lung-MAP Treatment Trial) NCT07393555Phase 241 sites📍 Berkeley📍 Palo Alto📍 Sacramento SWOG Cancer Research Network · Tests: Biospecimen Collection, Computed Tomography, Ivonescimab, Magnetic Resonance Imaging, Sacituzumab Govitecan Analysis of Circulating Tumor DNA Dynamics to Predict and Monitor Response to TKI in Patients With Advanced NSCLC. NCT06167460n/a1 site📍 Ho Chi Minh City Gene Solutions Risk-adapted, Proteomic-guided Systemic Therapy for Previously Untreated Advanced Non-small Cell Lung Cancer NCT07250477Phase 24 sites📍 Chico📍 Marysville📍 Sacramento University of California, Davis · Tests: Systemic (ICI)-based therapy informed by the PROphet CB assay and the CARG-TT assessment., Standard of Care A Study to Assess Adverse Events and Change in Disease Activity of Intravenous (IV) Telisotuzumab Adizutecan, Monotherapy or in Combination With Osimertinib, Compared to Standard of Care in Adult Participants With Locally Advanced or Metastatic EGFR-Mutated Non-Squamous Non-Small Cell Lung Cancer NCT07155187Phase 2, Phase 3117 sites📍 Springdale📍 Duarte📍 Irvine AbbVie · Tests: Telisotuzumab Adizutecan, Standard of Care, Osimertinib An Open-label, Single-arm Study of Prophylaxis for Datopotamab Deruxtecan (Dato-DXd) -Related Stomatitis in Eligible Patients With Metastatic or Inoperable Locally Recurrent Breast Cancer or Locally Advanced or Metastatic Epidermal Growth Factor Receptor-Mutated Non-small Cell Lung Cancer. NCT07357597Phase 441 sites📍 Tucson📍 Hot Springs📍 Little Rock AstraZeneca · Tests: Dexamethasone mouthwash, Datopotamab Deruxtecan (Dato-DXd) A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC NCT05543330Phase 1, Phase 21 site📍 Hangzhou Wuhan YZY Biopharma Co., Ltd. · Tests: M701 pleural infusion, Pleural drainage, Cisplatin pleural infusion Peptide Vaccine To Prevent Acquired Resistance In Patients With Advanced ALK+ NSCLC NCT05950139Phase 1, Phase 21 site📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: Peptide vaccine The EASE Study: Randomized Trial of a Novel Approach to Addressing Fear of Progression in Advanced Cancer NCT07636200NA2 sites📍 Aurora📍 Boulder University of Colorado, Boulder · Tests: Written Exposure-Based Coping Intervention (EASE), Usual Care Control Condition Testing Proton Craniospinal Radiation Therapy Versus the Usual Radiation Therapy for Leptomeningeal Metastasis, RADIATE-LM Trial NCT06500481Phase 358 sites📍 Phoenix📍 Little Rock📍 Encinitas NRG Oncology · Tests: Biospecimen Collection, Computed Tomography, Involved-Field Radiation Therapy, Lumbar Puncture, Magnetic Resonance Imag… PBF-1129 and Nivolumab for the Treatment of Recurrent or Metastatic Non-Small Cell Lung Cancer NCT05234307Phase 11 site📍 Columbus Dwight Owen · Tests: Adenosine A2B Receptor Antagonist PBF-1129, Biospecimen Collection, Nivolumab A Tool for Improving the Shared Decision-making Process in Patients With Non-small Cell Lung Cancer NCT06122064NA1 site📍 Rochester Mayo Clinic · Tests: Best Practice, Communication Intervention, Electronic Health Record Review, Survey Administration, Video Recording Molecular Landscape Analysis and Clinical Implications for NSCLC Patients With Rare Mutations NCT05701787n/a2 sites📍 Shanghai📍 Shanghai Shanghai Chest Hospital Dabrafenib and/or Trametinib Rollover Study NCT03340506Phase 438 sites📍 Scottsdale📍 Bethesda📍 Columbus Novartis Pharmaceuticals · Tests: dabrafenib, trametinib Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform NCT06349642n/a3 sites📍 Phoenix📍 Jacksonville📍 Rochester Mayo Clinic · Tests: Biospecimen Collection, Tissue Collection AI-HOPE Lung Cancer: Building a Predictive Tool for Metastatic Lung Cancer NCT06788366n/a1 site📍 Milan IRCCS San Raffaele · Tests: Immunotherapy, Chemotherapy Sacituzumab Govitecan and Bevacizumab for NSCLC Brain Metastases NCT06401824Phase 23 sites📍 Amsterdam📍 Groningen📍 Maastricht Maastricht University Medical Center · Tests: Sacituzumab Govitecan-Hziy 180 MG plus bevacizumab Combination of Atezolizumab and Pirfenidone in Second-line and Beyond NSCLC NCT04467723Phase 1, Phase 22 sites📍 Fairway📍 Kansas City University of Kansas Medical Center · Tests: Atezolizumab Gilteritinib for the Treatment of ALK NSCLC NCT06225427Phase 13 sites📍 Los Angeles📍 Washington D.C.📍 Ann Arbor University of Michigan Rogel Cancer Center · Tests: Biopsy, Biospecimen Collection, Computed Tomography, Echocardiography, Gilteritinib Characteristics of Advanced LUNG CANCER at the tIme of Diagnosis in a Large Italian Cohor NCT06076005n/a3 sites📍 Roma📍 Roma📍 Roma Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Tests: Advanced lung cancer patients' group
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