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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Malaria Infection

Laboratory Evaluation of Pregnancy Malaria Vaccine Candidates/In-vitro Testing of Pregnancy Malaria Vaccine Candidates NCT02471378n/a1 site📍 Bamako National Institute of Allergy and Infectious Diseases (NIAI… Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants NCT03937817n/a1 site📍 Bethesda National Institute of Allergy and Infectious Diseases (NIAI… A Revised Tafenoquine Dose to Improve Radical Cure for Vivax Malaria NCT06148792Phase 34 sites📍 Manaus📍 Arba Minch📍 Hanura Menzies School of Health Research · Tests: Tafenoquine, Primaquine A Study to Assess the Safety and Immunogenicity of a Vaccine Against Malaria in Healthy Children Aged 5-60 Months NCT07036159Phase 22 sites📍 Kigali📍 Kigali GlaxoSmithKline · Tests: RTS,S/AS01E vaccine Induced Blood-Stage Malaria in Healthy Malaria-Naive Adults to Assess the Safety and Infectivity of Plasmodium Vivax Challenge Agent and Evaluate Transmission in Mosquito Feeding Assays NCT06607003Phase 11 site📍 Bethesda National Institute of Allergy and Infectious Diseases (NIAI… · Tests: P. vivax challenge agent derived from PvHMB-CCE001 Platelet-Directed Whole Blood Transfusion Strategy for Malaria NCT05711485NA2 sites📍 Baltimore📍 Ndola Johns Hopkins Bloomberg School of Public Health · Tests: Whole blood transfusion Screening of Healthy Volunteers for Investigational Antimalarial Drugs, Malaria Vaccines, and Controlled Human Malaria Challenge NCT02639299n/a1 site📍 Bethesda National Institute of Allergy and Infectious Diseases (NIAI… PfSPZ-LARC2 Vaccine in Women of Child-bearing Potential (WOCBP) in Mali NCT07675785Phase 21 site📍 Bamako Sanaria Inc. · Tests: PfSPZ-LARC2 Vaccine, Normal Saline An Interventional Study to Compare the Efficacy and Safety of Tafenoquine (TQ) and Primaquine (PQ) When Either Are Taken Together With Chloroquine (CQ) for the Treatment of P. Vivax Malaria in Indian Participants Aged 2 Years and Older NCT06666491Phase 35 sites📍 Ahmedabad📍 Bikaner📍 Kolkata GlaxoSmithKline · Tests: Tafenoquine, Primaquine, Chloroquine Effectiveness of Malaria Vaccines in Reducing the Risk of Invasive Non-typhoidal Salmonella Disease NCT07416461n/a1 site📍 Kinshasa International Vaccine Institute · Tests: R21/Matrix-M malaria vaccine Field Trial of PfSPZ-LARC2 Vaccine in Burkinabe Adults NCT07385287Phase 21 site📍 Ouagadougou Sanaria Inc. · Tests: Genetically attenuated PfSPZ Vaccine, Normal Saline (0.9% Sodium Chloride) Safety, Tolerability and Efficacy of PfSPZ-LARC2 Vaccine Against CHMI in Malaria-Naïve Adults NCT06862453Phase 11 site📍 Tübingen Sanaria Inc. · Tests: Normal Saline (Placebo), PfSPZ-LARC2 Vaccine, PfSPZ Challenge (NF54) Introduction of Polymerase Chain Reaction (PCR) in Microbiology and Parasitology NCT07269314n/a1 site📍 Pavia Fondazione IRCCS Policlinico San Matteo di Pavia Focal Mass Drug Administration for the Prevention of Malaria in Pregnancy NCT07021430EARLY Phase 11 site📍 Kasese University of North Carolina, Chapel Hill · Tests: Dihydroartemisinin Piperaquine Observational Study of the Safety of Intravenous Artesunate Treatment of Pregnant Women and Their Infants NCT05285735n/a1 site📍 Piscataway Amivas Inc. An Observational Study to Assess Effectiveness and Safety of The R21/Matrix-M Malaria Vaccine NCT07009847n/a5 sites📍 Bousse📍 Toumodi📍 Yenagoa Serum Institute of India Pvt. Ltd. · Tests: Case control study of clinical malaria, Case control study of severe malaria, Case control study of death (all cause) Investigating the Pharmacokinetics of Tafenoquine in Healthy Papua New Guinean Children NCT07052162Phase 41 site📍 Madang Curtin University · Tests: Single dose tafenoquine (10 mg/kg) given with water, Single dose tafenoquine (10 mg/kg) given with fat Safety, Tolerability, Pharmacokinetics, and Mosquitocidal Activity of Lotilaner in Healthy Participants in Mali. NCT07758985Phase 11 site📍 Bamako Medicines for Malaria Venture · Tests: Cohort 1 low dose lotilaner with a high-fat meal, Cohort 1 low dose placebo with a high-fat meal, Cohort 2 high dose lo… FocaL Mass Drug Administration for Vivax Malaria Elimination NCT05690841Phase 31 site📍 Iquitos University of California, San Francisco · Tests: Focal Mass Drug Administration (fMDA) Comparison of Two Strategies for Administering the R21-Matrix M Vaccine in a Context of Seasonal Malaria Transmission in Chad NCT07038837Phase 41 site📍 Moïssala Epicentre · Tests: "Synchronised" arm (intervention) Safety of Antimalarials in the FIRst trimEster NCT06962319Phase 33 sites📍 Nanoro📍 Kisumu📍 Bamako Liverpool School of Tropical Medicine · Tests: dihydroartemisinin-piperaquine (DP), Pyronaridine-artesunate (PA), Artemether-lumefantrine First-in-Human Dose-escalation of GSK4425689A: Safety, Tolerability, and PK in Healthy Adults NCT07646353Phase 11 site📍 Manchester GlaxoSmithKline · Tests: GSK4425689A SC, GSK4425689A IV, Placebo ACT vs CQ With Tafenoquine for P. Vivax Mono-infection NCT05788094Phase 41 site📍 Mae Sot Shoklo Malaria Research Unit · Tests: Dihydroartemisinin-piperaquine plus tafenoquine (450 mg adult dose), Chloroquine plus Tafenoquine (450 mg adult dose), … Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection NCT00001645n/a1 site📍 Bethesda National Institute of Allergy and Infectious Diseases (NIAI… Safety and Efficacy of Imatinib in Combination With Artemether-Lumefantrine for Uncomplicated Malaria NCT07559370Phase 21 site📍 Kisumu Victoria Biomedical Research Institute · Tests: Artemether lumefantrine tablets, Artemether Lumefantrine and Imatinib Mesylate Assessing Vaccine Effectiveness of R21/Matrix-M Across Malaria Transmission Settings (AVERT) NCT07749911n/a21 sites📍 Boromo📍 Boromo📍 Houndé Clinton Health Access Initiative Inc. · Tests: R21/Matris-M Malaria vaccine Single Ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of LAI MMV055 Alone and in Combination With MMV371 in Healthy Participants NCT07011511Phase 11 site📍 Nottingham Medicines for Malaria Venture · Tests: MMV055 Dose 1, MMV055 Dose 2, MMV055 Dose 3, MMV055 Dose 4, MMV055 Dose 5 Host and Parasite Factors That Influence Susceptibility to Malaria Infection and Disease During Pregnancy and Early Childhood in Ouelessebougou and Bamako, Mali NCT01168271n/a2 sites📍 Bamako📍 Wolossébougou National Institute of Allergy and Infectious Diseases (NIAI… Clinical Aspects, Management and Surveillance of Febrile Illnesses in DRC NCT07345286n/a1 site📍 Kinshasa Institute of Tropical Medicine, Belgium Physiology and Pathologies Linked to Human Splenic Function : Direct and Ex-vivo Perfusion Explorations NCT06418256n/a5 sites📍 Clichy📍 Paris📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: Spleen, blood and plasma collection
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