🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

🧪

Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

🎯 Match trials to me

30 recruiting trials

for Malignant Brain Neoplasm

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors NCT07371663Phase 1, Phase 23 sites📍 Beijing📍 Zhengzhou📍 Hangzhou Beijing Tide Pharmaceutical Co., Ltd · Tests: TCC1727 tablet 90mg, TCC1727 tablet 120mg, TCC1727 tablet 160mg, benmelstobart Injection Pilot Study Evaluating Panitumumab-IRDye800 as an Optical Imaging Agent to Detect Intracranial Lesions During Neurosurgical Procedures NCT07493447EARLY Phase 11 site📍 Nashville Eben Rosenthal · Tests: Panitumumab-IRDye800 NK Cell Therapy for Malignant Solid Brain Tumors NCT07552233NA4 sites📍 Beijing📍 Qinhuangdao📍 Zhengzhou Peking University Third Hospital · Tests: Autologous NK cells Magnetic Resonance (MR) Imaging to Determine High Risk Areas in Patients With Malignant Gliomas and to Design Potential Radiation Plans and to Examine Metabolite Changes in Gliomas and Other Solid Tumors NCT00870129NA1 site📍 New York Memorial Sloan Kettering Cancer Center · Tests: MRI and advanced MRI sequences Educational Tools for the Improvement of Early Advance Care Planning in Adolescents and Young Adults With Advanced Solid Tumors and High-Grade Brain Tumors NCT07174661NA1 site📍 Scottsdale Mayo Clinic · Tests: Advance Care Planning, Educational Intervention, Electronic Health Record Review, Survey Administration Evaluation of Clinical Efficacy and Safety of Specific Mode Electroacupuncture Stimulation for Paclitaxel Across BBB Delivery in Patients With Postoperative Recurrence of Malignant Glioma: A Single-arm Trial NCT06818331Phase 21 site📍 China The Third Affiliated hospital of Zhejiang Chinese Medical U… · Tests: SMES+PTX, Paclitaxel, Specific mode electroacupuncture stimulation Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China NCT05672043n/a1 site📍 Beijing Beijing Tiantan Hospital Post-Operative Dosing of Dexamethasone in Patients With Brain Tumors After a Craniotomy, PODS Trial NCT06132685Phase 21 site📍 Atlanta Emory University · Tests: Biospecimen Collection, Computed Tomography, Dexamethasone, Magnetic Resonance Imaging, Questionnaire Administration 000860: A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations NCT05588141Phase 1, Phase 22 sites📍 Jacksonville📍 Bethesda National Cancer Institute (NCI) · Tests: Zotiraciclib Non-invasive Glioma Characterization Through Molecular Imaging NCT03684109NA1 site📍 Miami University of Miami · Tests: 3T MRI Scanner Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery NCT03184038NA2 sites📍 Sewell📍 Philadelphia Sidney Kimmel Comprehensive Cancer Center at Thomas Jeffers… · Tests: Cognitive Assessment, Stereotactic Radiosurgery, Stereotactic Body Radiation Therapy, Quality-of-Life Assessment Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site📍 Bethesda National Institute of Neurological Disorders and Stroke (NI… · Tests: LMP744, Conventional Surgery or Biopsy Chronic CED of TPT for Recurrent Malignant Glioma NCT06666712Phase 11 site📍 New York Jeffrey N. Bruce · Tests: Topotecan The Impact of Paramedic Training in Simulation on the Experience of Patients Treated for Malignant Brain Tumors in Neurosurgery (IPSIMANON) NCT06962215NA11 sites📍 Brest📍 Amiens📍 Angers University Hospital, Brest · Tests: Paramedic training Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology NCT04988009n/a1 site📍 Houston M.D. Anderson Cancer Center · Tests: Electronic Health Record Review, Survey Administration An Investigational Scan (64Cu-DOTA-Trastuzumab PET/MRI) in Imaging Patients With HER2+ Breast Cancer With Brain Metastasis NCT05376878Phase 41 site📍 Duarte City of Hope Medical Center · Tests: Copper Cu 64-DOTA-Trastuzumab, Magnetic Resonance Imaging, Positron Emission Tomography, Trastuzumab, Trastuzumab Derux… Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus NCT02479698Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Allogeneic BK-specific Cytotoxic T-lymphocytes, Laboratory Biomarker Analysis HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors NCT03911388Phase 13 sites📍 Birmingham📍 St Louis📍 Houston M.D. Anderson Cancer Center · Tests: G207 The SUPRAMAX Study: Supramaximal Resection Versus Maximal Resection for High-Grade Glioma Patients (ENCRAM 2201) NCT06118723n/a8 sites📍 San Francisco📍 Boston📍 Leuven Jasper Gerritsen · Tests: Supramaximal resection, Maximal safe resection Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain NCT05588453Phase 1, Phase 21 site📍 Columbus Kari Kendra · Tests: Natural Killer Cell Therapy, Temozolomide Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions NCT04047264NA1 site📍 Rochester Mayo Clinic · Tests: Microdialysis, Magnetic Resonance Imaging, Computed Tomography Feasibility of FMISO in Brain Tumors NCT03649880Phase 21 site📍 Portland OHSU Knight Cancer Institute · Tests: ¹⁸F-Fluoromisonidazole, Computed Tomography, Magnetic Resonance Imaging, Positron Emission Tomography, Oxygen Therapy FearLess in NeuroOncology NCT06989086NA1 site📍 Richmond Virginia Commonwealth University · Tests: Fearless in Neuro-Oncology Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT) NCT06193759Phase 11 site📍 Washington D.C. Children's National Research Institute · Tests: Multi-tumor antigen specific cytotoxic T lymphocytes (TSA-T) directed against proteogenomically determined personalized… Virus-Based Gene Therapy (AdV-HSV1-TK and AdV-Flt3L) in Combination With Valacyclovir for the Treatment of Pediatric and Young Adult Patients With Resectable, Recurrent Primary Malignant Brain Tumors NCT06914479Phase 11 site📍 Ann Arbor University of Michigan Rogel Cancer Center · Tests: Ad-hCMV-Flt3L, Ad-hCMV-TK, Biospecimen Collection, Magnetic Resonance Imaging, Survey Administration Safety Study of the Repeated Opening of the Blood-brain Barrier With the SonoCloud® Device to Treat Malignant Brain Tumors in Pediatric Patients NCT05293197Phase 13 sites📍 Paris📍 Paris📍 Villejuif Assistance Publique - Hôpitaux de Paris · Tests: SonoCloud® (9 transducers) Evaluation of 18F-Fluciclovine Positron Emission Tomography - Magnetic Resonance Imaging (PET-MRI) in LGG NCT05555550EARLY Phase 11 site📍 Philadelphia Children's Hospital of Philadelphia · Tests: 18F-Fluciclovine Window of Opportunity Study of DSP-0390 in Gliomas NCT06636162EARLY Phase 11 site📍 St Louis Washington University School of Medicine · Tests: DSP-0390 A Rollover Study of NBM-BMX in Combination With Temozolomide in Patients With Newly Diagnosed Glioblastoma NCT07569042Phase 1, Phase 23 sites📍 Kaohsiung City📍 Taichung📍 Taoyuan City Novelwise Pharmaceutical Corporation · Tests: NBM-BMX Capsule, Temozolomide Sitagliptin in Recurrent/Progressive Grade 4 Glioma NCT07541781Phase 11 site📍 Iowa City Kailin Yang, MD, PhD · Tests: Sitagliptin, Bevacizumab
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy