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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Malignant Head and Neck Neoplasm

Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers NCT04221893NA2 sites📍 San Francisco📍 Walnut Creek University of California, San Francisco · Tests: Radiation Therapy (RT) Prediction of Malignant Transformation of Oral Leukoplakia Using a MAGE-A-based Immunoscore NCT03975322n/a1 site📍 Erlangen University of Erlangen-Nürnberg Medical School A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors NCT06043466Phase 12 sites📍 Hangzhou📍 Hangzhou Chongqing Precision Biotech Co., Ltd · Tests: CEA-targeted CAR-T cells A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites📍 Duarte📍 Los Angeles📍 San Francisco Nurix Therapeutics, Inc. · Tests: NX-1607, Paclitaxel GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors NCT06265025Phase 1, Phase 24 sites📍 Goyang-si📍 Seoul📍 Seoul GeneMedicine Co., Ltd. · Tests: GM103 (Part A), GM103 (Part B), GM103 and Pembrolizumab (Part C) A Study Evaluating the Safety and Efficacy of AUR107 in Patients With Relapsed Advanced Malignancies (SHAKTI-1) NCT05865002Phase 137 sites📍 Vijayawada📍 Visakhapatnam📍 Chandigarh Aurigene Discovery Technologies Limited · Tests: AUR107 Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck Cancer NCT03010150n/a1 site📍 Houston M.D. Anderson Cancer Center · Tests: Biospecimen Collection, Questionnaire Administration DETERMINE Trial Treatment Arm 07: Dabrafenib in Combination With Trametinib in Adult, Paediatric and Teenage/Young Adult Patients With BRAF V600 Mutation-Positive Cancers. NCT07440290Phase 2, Phase 327 sites📍 Belfast📍 Birmingham📍 Birmingham Cancer Research UK · Tests: Dabrafenib, Trametinib Comparative Study Between (FC-SEMS) and (PC-SEMS) in the Palliation of Dysphagia Due to Malignant Neoplasm of Esophagus. NCT06070376NA1 site📍 São Paulo Instituto do Cancer do Estado de São Paulo · Tests: Fully Covered Esophageal Prosthesis (FC-SEMS), Partially Covered Esophageal Prosthesis (PC-SEMS) Data Collection for the Assessment of Acute and Late Normal Tissue in Patients Treated With Proton Therapy NCT00991094n/a1 site📍 Houston M.D. Anderson Cancer Center · Tests: Quality-of-Life Assessment, Questionnaire Administration Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform NCT06349642n/a3 sites📍 Phoenix📍 Jacksonville📍 Rochester Mayo Clinic · Tests: Biospecimen Collection, Tissue Collection Chemoradiotherapy in Unresectable Esophageal Cancer NCT04278287Phase 1, Phase 25 sites📍 Anyang📍 Changsha📍 Nanjing Cancer Institute and Hospital, Chinese Academy of Medical S… · Tests: Radiotherapy, Albumin-Bound Paclitaxel, Cisplatin Single Dose Investigator Initiated Pilot Study to Investigate CYTALUX (Pafolacianine) for Intraoperative Detection of Malignant Tissue in Subjects Undergoing Surgical Resection for Cancer. NCT07039526Phase 21 site📍 Dallas John Waters · Tests: CYTALUX™ (pafolacianine) injection preoperatively Distance-Based Exercise to Preserve Function and Prevent Disability NCT07059884NA23 sites📍 Dublin📍 Fremont📍 Fresno Alliance for Clinical Trials in Oncology · Tests: Exercise intervention, Telemedicine, Aerobic Exercise Intervention, Exercise Intervention, Accelerometry Rate of Malignant Transformation and Clinical Characteristics Among an Oral Lichen Planus Cohort: a Retrospective Center Experience NCT06934863n/a1 site📍 Roma Catholic University of the Sacred Heart Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site📍 Jacksonville Mayo Clinic · Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration CEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid Tumors NCT07179692Phase 11 site📍 Hefei Chongqing Precision Biotech Co., Ltd · Tests: CEA-targeted CAR-T cells, CEA-targeted CAR-T cells, CEA-targeted CAR-T cells Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors NCT04119024Phase 13 sites📍 Duarte📍 Los Angeles📍 Stanford Anusha Kalbasi · Tests: Biopsy, Biospecimen Collection, Computed Tomography, Cyclophosphamide, Fludarabine Phosphate Esophageal Self-expandable Metal Stent for Malignant Strictures: a Safety and Efficacy Study NCT06364553NA1 site📍 Rotterdam Erasmus Medical Center · Tests: Esophageal self-expandable metal stent High-Resolution PET-CT Imaging for Surgical Margin Visualization NCT06915454NA1 site📍 Nashville Vanderbilt-Ingram Cancer Center · Tests: Intra-op PET/CT Specimen Scanner FL-261 Imaging for Cancer Diagnosis and Staging NCT07510321n/a1 site📍 Wuhan Union Hospital, Tongji Medical College, Huazhong University… · Tests: [68Ga]Ga-FL-261 PET Imaging / [111In]In-FL-261 SPECT Imaging Milaberon in Advanced Solid Tumors: an Open, Multicenter Clinical Study NCT06534762Phase 21 site📍 Hangzhou Zhejiang Provincial People's Hospital · Tests: Mirabegron A Machine Learning-Based Risk Prediction Model for Head and Neck Cancerous Lesions NCT07532538n/a1 site📍 Nanjing The Affiliated Nanjing Drum Tower Hospital of Nanjing Unive… RAPA-201 Therapy of Solid Tumors NCT05144698Phase 1, Phase 21 site📍 Hackensack Rapa Therapeutics LLC · Tests: RAPA-201 Rapamycin Resistant T Cells, Chemotherapy Prior to RAPA-201 Therapy, Pembrolizumab (PD-1 Blocking Antibody) Safety and Efficacy of NEO212 in Patients With Astrocytoma IDH-mutant, Glioblastoma IDH-wildtype or Brain Metastasis NCT06047379Phase 1, Phase 28 sites📍 Beverly Hills📍 Glendale📍 Los Angeles Neonc Technologies, Inc. · Tests: NEO212 Oral Capsule, Ipilimumab, Pembrolizumab, Nivolumab, Regorafenib Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial NCT04693377NA1 site📍 Houston M.D. Anderson Cancer Center · Tests: Cryosurgery, Quality-of-Life Assessment, Stereotactic Body Radiation Therapy IACS-6274 With or Without Bevacizumab and Paclitaxel for the Treatment of Advanced Solid Tumors NCT05039801Phase 11 site📍 Houston M.D. Anderson Cancer Center · Tests: Bevacizumab, Glutaminase-1 Inhibitor IACS-6274, Paclitaxel, Capivasertib Clinical Application of PET Imaging Targeting CLDN18.2 in Malignant Tumors NCT07301814n/a1 site📍 Wuhan Union Hospital, Tongji Medical College, Huazhong University… · Tests: Specific PET imaging agents targeting CLDN18.2 A Study of DEG6498 in Participants With Solid Tumors NCT07244835Phase 13 sites📍 Beijing📍 Beijing📍 Guangzhou Degron Therapeutics Co. · Tests: DEG6498 CD70-targeted immunoPET Imaging of Malignant Cancers NCT06852638Phase 21 site📍 Shanghai RenJi Hospital · Tests: [18F]F-RESCA-RCCB6, [18F]F-RESCA-R8B4, [68Ga]Ga-NOTA-R8B4, [18F]F-RESCA-RD06, [68Ga]Ga-NOTA-RD06
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