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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Malignant Pleural Mesothelioma

A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites📍 Aurora📍 Lake Mary📍 Lebanon 7 Hills Pharma, LLC · Tests: Alintegimod, Ipilimumab, Nivolumab dENdritic Cell Therapy Combined With SURgEry in Mesothelioma NCT05304208Phase 11 site📍 Rotterdam Erasmus Medical Center · Tests: Mesopher Study of Volrustomig as Monotherapy or in Combination With Anti- Cancer Agents in Participants With Advanced/Metastatic Solid Tumors NCT06535607Phase 298 sites📍 Los Angeles📍 Baltimore📍 New York AstraZeneca · Tests: Volrustomig, Cisplatin, Carboplatin, Paclitaxel, 5-FU A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites📍 Duarte📍 Los Angeles📍 San Francisco Nurix Therapeutics, Inc. · Tests: NX-1607, Paclitaxel Partial Pleurectomy (Surgery) for Unresectable Pleural Mesothelioma NCT07126509NA1 site📍 Chicago University of Chicago · Tests: Partial Pleurectomy Trial Assessing Fianlimab Plus Cemiplimab Plus Chemotherapy or Cemiplimab Plus Chemotherapy in Patients With Pleural Mesothelioma NCT07234058Phase 237 sites📍 Aix-en-Provence📍 Amiens📍 Angers Intergroupe Francophone de Cancerologie Thoracique · Tests: Cemiplimab, Fianlimab, Pemetrexed (Alimta), Cisplatin, Carboplatin (AUC 5) SW-682 in Advanced Solid Tumors NCT06251310Phase 18 sites📍 Scottsdale📍 Los Angeles📍 Sacramento SpringWorks Therapeutics, Inc., a healthcare company of Mer… · Tests: SW-682, Combination Therapy Evaluating Ivonescimab as a Potential Treatment for Pleural Mesothelioma Patients Whose Cancer Has Returned After Previous Immunotherapy and Chemotherapy NCT06840834Phase 221 sites📍 Besançon📍 Brest📍 Caen Intergroupe Francophone de Cancerologie Thoracique · Tests: Ivonescimab TLN-499 in Combination With Venetoclax in Patients With Relapsed/Refractory Solid Tumors NCT07713732Phase 13 sites📍 Camperdown📍 Malvern📍 Nedlands Treeline Biosciences, Inc. · Tests: TLN-499, Venetoclax Efficacy and Safety of Ivonescimab Plus Pemetrexed and Platinum-Based Chemotherapy in Advanced Malignant Pleural Mesothelioma NCT07885319Phase 1, Phase 23 sites📍 Shanghai📍 Shanghai📍 Chengdu Ruijin Hospital · Tests: Ivonescimab Combined With Chemotherapy First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis. NCT06946498NA1 site📍 Athens National and Kapodistrian University of Athens · Tests: Local Anesthesia Thoracoscopy, Pleuroscopy with Rigid Thoracoscope and Forceps biopsies Pembrolizumab in Combination With Chemotherapy and Image-Guided Surgery for Malignant Pleural Mesothelioma (MPM) NCT03760575Phase 11 site📍 Philadelphia Abramson Cancer Center at Penn Medicine · Tests: Pembrolizumab, Indocyanine Green (ICG) Image-Guided Surgery, Cisplatin, Pemetrexed Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease NCT07192900Phase 11 site📍 Pittsburgh David Bartlett, MD · Tests: locally manufactured adoptive cellular therapy (ACT) product, Interleukin-2 Multicenter Single-Arm Study of Ivonescimab (AK112) Combined with Chemotherapy in Pretreated Pleural Mesothelioma NCT06875076Phase 21 site📍 Changchun The First Hospital of Jilin University · Tests: Ivonescimab Combined With Chemotherapy Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary Tumors NCT07443020Phase 11 site📍 Pittsburgh Allegheny Singer Research Institute (also known as Alleghen… · Tests: locally manufactured adoptive cellular therapy (ACT) product, Interleukin-2 (IL-2) INTEGRATIVE "MULTI-OMICS" AND FUNCTIONAL PLATFORM FOR THE COMPLETE DIAGNOSTIC CHARACTERIZATION OF TUMORS: THE ITALIAN TUMOR CHEMOGENOMIC PROFILER (IT-TCP) NCT07403630NA2 sites📍 Palermo📍 Perugia Azienda Ospedaliero-Universitaria di Parma · Tests: Functional tests, Multi-omics analyses, Cytogenetics/ FISH Neoadjuvant Durvalumab and Tremelimumab With and Without Chemotherapy for Mesothelioma NCT05932199Phase 1, Phase 22 sites📍 Durham📍 Houston Baylor College of Medicine · Tests: Durvalumab / tremelimumab, Platinum cisplatin or carboplatin and pemetrexed chemotherapy plus durvalumab/tremelimumab The IMmunotherapy Pleural 5-ALA PDT NCT04400539Phase 21 site📍 Lille University Hospital, Lille · Tests: intrapleural photodynamic therapy with videothoracoscopy, Nivolumab Injection A Study of Sacituzumab Govitecan in People With Mesothelioma NCT06477419Phase 27 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Sacituzumab govitecan-hziy The Diagnostic Accuracy and Clinical Value of FAPI PET in Pleural Mesothelioma NCT06790082Phase 21 site📍 Aalborg Aalborg University Hospital · Tests: [68Ga]Ga-FAPI-46 PET/CT A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression NCT06051695Phase 1, Phase 212 sites📍 Gilbert📍 La Jolla📍 Los Angeles A2 Biotherapeutics Inc. · Tests: A2B694, A2B543, xT CDx with HLA-LOH Assay TTFields in General Routine Clinical Care in Patients With Pleural Mesothelioma Study NCT05538806n/a23 sites📍 Gauting📍 Regensburg📍 Harburg NovoCure Ltd. · Tests: TTFields NEoadjuvant Chemotherapy and Immunotherapy for a Selected Group of Inoperable Pleural Mesothelioma Patients (NECIM): a Feasibility Study NCT07121374Phase 1, Phase 21 site📍 Edegem University Hospital, Antwerp · Tests: Neoadjuvant chemo-immunotherapy, Extended pleurectomy/decortication in case of reaching operability Multidimensional Omics Analysis in Malignant Pleural Mesothelioma NCT07561190n/a4 sites📍 Catania📍 Naples📍 Reggio Emilia Azienda USL Reggio Emilia - IRCCS Evaluation of Cell Changes in Blood and Tissue in Cancers of the Lung, Esophagus and Lung Lining NCT00242723n/a1 site📍 Bethesda National Cancer Institute (NCI) A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas NCT04104776Phase 1, Phase 280 sites📍 Tampa📍 Atlanta📍 Chicago Novartis Pharmaceuticals · Tests: Tulmimetostat, Enzalutamide Integration of the PD-L1 Inhibitor Atezolizumab and WT1/DC Vaccination Into Platinum/Pemetrexed-based First-line Treatment for Epithelioid Malignant Pleural Mesothelioma NCT05765084Phase 1, Phase 23 sites📍 Edegem📍 Ghent📍 Sint-Niklaas University Hospital, Antwerp · Tests: Dendritic cell vaccination, Atezolizumab, Platinum/pemetrexed based chemotherapy APG-2449 in Patients With Advanced Solid Tumors NCT03917043Phase 19 sites📍 Beijing📍 Fuzhou📍 Fuzhou Ascentage Pharma Group Inc. · Tests: APG-2449 TRAcking Thoracic Cancer Evolution Through Therapy (Rx) EVO NCT05628376n/a1 site📍 London University College, London Dual-Target MSLN/FAP CAR-NK Cells for Pleural and Peritoneal Mesothelioma NCT07510815Phase 1, Phase 21 site📍 Shenzhen Beijing Biotech · Tests: EB-MF-CAR-NK-01, Fludarabine, Cyclophosphamide
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