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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Melanoma (Skin) Stage IV

Versatile Ampification Single-Molecule Detection in Liquid Biopsy NCT05940311n/a1 site๐Ÿ“ Rome Regina Elena Cancer Institute ยท Tests: Blood sampling in addition to the blood normally required for their clinical management, Blood plasma and circulating tโ€ฆ Binimetinib and Imatinib for Unresectable Stage III-IV KIT-Mutant Melanoma NCT04598009Phase 22 sites๐Ÿ“ La Jolla๐Ÿ“ San Francisco University of California, San Francisco ยท Tests: Binimetinib, Imatinib Intralesional Influenza Vaccine for the Treatment of Stage I-IV Melanoma NCT04697576Phase 11 site๐Ÿ“ Columbus Carlo Contreras ยท Tests: Ipilimumab, Nivolumab, Pembrolizumab, Quadrivalent Inactivated Influenza Vaccine, Resection Time-of-Day Specified Immunotherapy for Advanced Melanoma, The TIME Trial NCT07155317Phase 22 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Ipilimumab, Magnetic Resonance Imaging Pharmacokinetics, Safety, and Immunogenicity Comparison of Bmab1700 and Opdivoยฎ as Adjuvant Monotherapy in Participants With Melanoma NCT07476326Phase 146 sites๐Ÿ“ Bento Gonรงalves๐Ÿ“ Ijuรญ๐Ÿ“ Parรก Biocon Biologics UK PLC ยท Tests: Bmab1700, Opdivo A Study Assessing KB707 for the Treatment of Locally Advanced or Metastatic Solid Tumors NCT05970497Phase 1, Phase 215 sites๐Ÿ“ Los Angeles๐Ÿ“ Rancho Santa Margarita๐Ÿ“ Weston Krystal Biotech, Inc. ยท Tests: KB707, Opdualag, KEYTRUDA ยฎ( Pembrolizumab) A Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory Melanoma NCT06624644Phase 2, Phase 39 sites๐Ÿ“ Newport Beach๐Ÿ“ San Francisco๐Ÿ“ Stanford Linnaeus Therapeutics, Inc. ยท Tests: LNS8801, Pembrolizumab, Chemotherapy (dacarbazine or temozolomide), Immunotherapy (Pembrolizumab), Immunotherapy (nivolโ€ฆ Long-Term Follow-up of Patients Treated With Miltenyi Cell and Gene Therapies NCT06508775NA7 sites๐Ÿ“ Berlin๐Ÿ“ Cologne๐Ÿ“ Erlangen Miltenyi Biomedicine GmbH ยท Tests: MB-CART19.1, MB-CART20.1, MB-CART2019.1 Neoadjuvant and Adjuvant Anti-PD1 or Combinations for Locoregionally Advanced Melanoma NCT06295159Phase 21 site๐Ÿ“ Tampa H. Lee Moffitt Cancer Center and Research Institute ยท Tests: Nivolumab, Nivolumab + Relatlimab, Ipilimumab Dabrafenib and/or Trametinib Rollover Study NCT03340506Phase 438 sites๐Ÿ“ Scottsdale๐Ÿ“ Bethesda๐Ÿ“ Columbus Novartis Pharmaceuticals ยท Tests: dabrafenib, trametinib Cryoablation Combined With Hepatic Arterial Infusion of Iparomlimab and Tuvonralimab (QL1706), Intravenous Dacarbazine, and Oral Lenvatinib in Patients With Liver Metastases From Malignant Melanoma: a Single-arm, Phase II, Prospective Trial NCT07847359Phase 21 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Cryoablation, Iparomlimab and Tuvonralimab, Dacarbazine, Lenvatinib Natural Killer Cell Therapy (UD TGFbetai NK Cells) and Temozolomide for the Treatment of Stage IV Melanoma Metastatic to the Brain NCT05588453Phase 1, Phase 21 site๐Ÿ“ Columbus Kari Kendra ยท Tests: Natural Killer Cell Therapy, Temozolomide Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer NCT05896839Phase 1, Phase 226 sites๐Ÿ“ La Jolla๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Ipilimumab, Kidney Biopsy Anti-PD 1 Brain Collaboration + Radiotherapy Extension (ABC-X Study) NCT03340129Phase 29 sites๐Ÿ“ Sydney๐Ÿ“ Waratah๐Ÿ“ Wollstonecraft Melanoma Institute Australia ยท Tests: Ipilimumab, Nivolumab, Stereotactic Radiotherapy, Salvage therapy Predictive Clinical Features for Response to Adjuvant Immunotherapy in Stage II,III and IV Resected Melanoma NCT05527795n/a1 site๐Ÿ“ Pierre-Bรฉnite Hospices Civils de Lyon ยท Tests: Frequency and duration of response to adjuvant immunotherapy according to clinical features, Frequency of each type of โ€ฆ Dietary Fiber to Induce Gut Microbiota-mediated Response to Immunotherapy in Melanoma. NCT07686835Phase 22 sites๐Ÿ“ Nijmegen๐Ÿ“ Groningen Radboud University Medical Center ยท Tests: Dried chicory roots, Placebo To Evaluate the Safety and Efficacy of ADP-TILIL7 in Patients With Locally Advanced or Metastatic Melanoma NCT06204991Phase 12 sites๐Ÿ“ Herlev๐Ÿ“ Herlev Inge Marie Svane ยท Tests: ADP-TILIL7, Cyclophosphamide, Fludarabine Phosphate, Proleukin Efficacy and Safety of Neoadjuvant Cadonilimab Plus High-Dose Recombinant Human Interferon ฮฑ1b in Stage III/IV Melanoma. NCT07586904EARLY Phase 11 site๐Ÿ“ Xi'an Xijing Hospital ยท Tests: Cadonilimab and Recombinant Human Interferon ฮฑ1b Combination Therapy Urinary Microbiome as a Biomarker for Melanoma Diagnosis and Response Prediction to Systemic Tumour Therapy NCT07635732n/a1 site๐Ÿ“ Gratwein Medical University of Graz Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors NCT04119024Phase 13 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Stanford Anusha Kalbasi ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Cyclophosphamide, Fludarabine Phosphate Binimetinib Plus Encorafenib Real Life Investigation of Next Generation Melanoma Treatment NCT04045691n/a59 sites๐Ÿ“ Graz๐Ÿ“ Innsbruck๐Ÿ“ Klagenfurt Pierre Fabre Pharma GmbH ยท Tests: Encorafenib, Binimetinib Interleukin-6 Receptor Inhibitor Sarilumab in Combination With Ipilimumab, Nivolumab and Relatlimab in Patients With Unresectable Stage III or Stage IV Melanoma NCT05428007Phase 24 sites๐Ÿ“ Los Angeles๐Ÿ“ Boston๐Ÿ“ Boston NYU Langone Health ยท Tests: Sarilumab, Ipilimumab Injection, Nivolumab/Relatlimab A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head) NCT06246916Phase 3113 sites๐Ÿ“ Chandler๐Ÿ“ Gilbert๐Ÿ“ Tucson Regeneron Pharmaceuticals ยท Tests: fianlimab, cemiplimab, relatlimab+nivolumab A Study to Investigate the Efficacy and Safety of an Infusion of IOV-4001 in Adult Participants With Unresectable or Metastatic Melanoma or Stage III or IV Non-small-cell Lung Cancer NCT05361174Phase 1, Phase 211 sites๐Ÿ“ Los Angeles๐Ÿ“ Miami๐Ÿ“ Orlando Iovance Biotherapeutics, Inc. ยท Tests: IOV-4001 Predictive Factors of Complete Response to Immunotherapy in Metastatic Melanoma: a Single-center Retrospective Study Between 2013 and 2021 NCT07302607n/a1 site๐Ÿ“ Strasbourg University Hospital, Strasbourg, France A Study of Radiation Therapy to Treat Solid Tumor Cancer That Has Spread to Soft Tissue NCT05837767NA7 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: Palliative radiotherapy MC1R-targeted Alpha-particle Monotherapy and Combination Therapy Trial With Nivolumab in Adults With Advanced Melanoma NCT05655312Phase 1, Phase 216 sites๐Ÿ“ Orange๐Ÿ“ Jacksonville๐Ÿ“ Miami Perspective Therapeutics ยท Tests: [203Pb]VMT01, [212Pb]VMT01, Nivolumab FMT to Convert Response to Immunotherapy NCT05251389Phase 1, Phase 21 site๐Ÿ“ Amsterdam The Netherlands Cancer Institute ยท Tests: Fecal microbiota transplantation Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial NCT04693377NA1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Cryosurgery, Quality-of-Life Assessment, Stereotactic Body Radiation Therapy
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