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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Mental Disorders, Severe

A Trial of Dextromethorphan and Bupropion Sustained-Release Tablets in Patients With Major Depressive Disorder NCT06958692Phase 31 site📍 Beijing CSPC Ouyi Pharmaceutical Co., Ltd. · Tests: Dextromethorphan and Bupropion Sustained-Release Tablets, Placebo Does Semaglutide Improve Depressive Symptoms in Patients With Major Depressive Disorder and Overweight or Obesity NCT07136714Phase 41 site📍 Hillerød Nordsjaellands Hospital · Tests: Semaglutide Injectable Product, Placebo Near Infrared Spectroscopy (NIRS) for Assessment of Depression NCT04061148NA1 site📍 San Francisco University of California, San Francisco · Tests: NIRSIT Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a1 site📍 Sioux Falls Sanford Health Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits NCT06728774NA1 site📍 Portland Portland VA Medical Center · Tests: Motivationally Enhanced Compensatory Cognitive Training for Major Depressive Disorder (ME-CCT-MDD), Goal-focused Suppor… Linking Affective Dynamics in Response to Daily Stress to Peripheral Vascular Function in Working Age Adults NCT06860724NA1 site📍 Newark University of Delaware · Tests: NG-nitro-L-arginine methyl ester (L-NAME) Impact and Determinants of Success of a Mobile Multidisciplinary Intervention System Specialized in Pain Management for Patients With Moderate to Severe Intellectual Development Disorder, Isolated or Associated With an ASD or Multiple Disability NCT07302048NA1 site📍 Brest University Hospital, Brest · Tests: MoDIDol intervention Gender Differences in Depression Severity, Gender-Sensitive Symptoms, Resilience, and Stigma in Major Depressive Disorder NCT07474363n/a1 site📍 Eskişehir Eskisehir Osmangazi University Cannabis and Processing Emotions Study NCT06907979NA1 site📍 Auburn Auburn University · Tests: TMS - Sham, TMS - Active iTBS, TMS - Active cTBS Psychoeducational Group for Depression NCT06467474NA1 site📍 São Paulo Ricardo Alberto Moreno, M.D., Ph.D. · Tests: PEG-D program, TAU Lifestyle Interventions to Prevent cOgnitive Deficits in Subjects With Depressive Symptoms: From mEchanisms to Clinical pRactice NCT07462013NA1 site📍 Taichung National Science and Technology Council, Taiwan · Tests: Soybean oil (Standard treatment), Eicosapentaenoic acid (omega-3 fatty acid) Efficacy of Chronotherapeutic Combination for Major Depressive Episode With Insomnia NCT07120880Phase 31 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: AD + SHR + active LT and extended-release melatonin 2mg, AD + SHR + active LT and placebo melatonin, AD + SHR + placebo… Multicenter Study of Lumateperone for the Treatment of Bipolar Depression in Pediatric Patients NCT06372964Phase 368 sites📍 Dothan📍 Little Rock📍 Anaheim Intra-Cellular Therapies, Inc. · Tests: Lumateperone, Placebo The Effect of PROSE or Scleral Lenses on Mental Health NCT07195721n/a1 site📍 Needham Boston Sight Singula Phase 0.1 Primary Care Pilot NCT07834684n/a2 sites📍 Brentwood📍 Mount Kisco Singula Health, Inc. A Study to Evaluate the Maintenance Effect of Osavampator as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD) NCT07196501Phase 361 sites📍 Oceanside📍 Orange📍 San Jose Neurocrine Biosciences · Tests: Osavampator, Placebo Effect of Psilocybin and Structured Integrated Reframing Therapy on Gut-Brain Axis Biomarkers and Depression in Major Depressive Disorder NCT07703722Phase 33 sites📍 Islamabad📍 Peshawar📍 Peshawar Khyber Medical University Peshawar · Tests: Psilocybin, Structured Integrated Reframing Therapy (SIRT), Selective Serotonin Reuptake Inhibitor (SSRI) Taking Action for College Students NCT06700902NA1 site📍 Philadelphia Temple University · Tests: Taking Action Evaluation of Radically Open Dialectical Behavior Therapy for Youth At Risk for Developing Severe and Enduring Eating Disorders NCT06792071NA1 site📍 Uppsala Uppsala University Hospital · Tests: Radically Open Dialectical Behavior Therapy (RO DBT) Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of Depression NCT06610305Phase 41 site📍 Chapel Hill University of North Carolina, Chapel Hill · Tests: Transdermal estradiol, Progesterone, Transdermal placebo patch, placebo capsule Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism NCT07091279Phase 22 sites📍 Staten Island📍 White Plains Jeremy Veenstra-vanderweele · Tests: Propranolol, Placebo Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation NCT06763081n/a2 sites📍 Winnipeg📍 Winnipeg University of Manitoba · Tests: Not applicable- observational study Cannabidiol as an add-on Treatment During Inpatient Alcohol Cessation : CBD-OH NCT05860699Phase 212 sites📍 Créteil📍 Clamart📍 Clermont-Ferrand Assistance Publique - Hôpitaux de Paris · Tests: Placebo, Half dose CBD, Full dose CBD Closed-Loop Deep Brain Stimulation for Major Depression NCT04004169NA1 site📍 San Francisco Andrew Krystal · Tests: Stimulation-ON, Stimulation-OFF, Stimulation-ON Active Control The Efficacy And Safety Of Mitizodone Phosphate Tablets In The Treatment of Patient With Major Depressive Disorder NCT04984512Phase 2, Phase 31 site📍 Dongguan Sunshine Lake Pharma Co., Ltd. · Tests: Mitizodone Phosphate tablets, Placebo-matching tablets One-Day cTBS Over the Precuneus NCT07758010NA1 site📍 Belmont Mclean Hospital · Tests: Precuneus-targeted continuous theta-burst stimulation, Left dorsolateral prefrontal cortex intermittent theta-burst sti… Milk Fat Globule Membrane-Enhanced RUTF for Children With Severe Acute Malnutrition NCT06869850NA10 sites📍 Bandajuma📍 Bandasuma📍 Bendu Malen Washington University School of Medicine · Tests: MFGM-RUTF (milk fat globule membrane ready-to-use therapeutic food), S-RUTF (standard ready-to-use therapeutic food), A… Home tDCS for the Treatment of Major Depression. NCT07510880NA3 sites📍 L'Hospitalet de Llobregat📍 Mataró📍 Sabadell Ionclinics & Deionic SL · Tests: Accelerated protocol of home Transcranial direct current stimulation, Conventional protocol of home Transcranial direct… The Impact of AMPA Receptor Blockade on Ketamine's Anti-Suicidal Effects NCT05786066Phase 21 site📍 West Haven Yale University · Tests: Perampanel 6 MG, Ketamine, Placebo The Friendship Bench Plus Trial NCT06384209NA1 site📍 Harare University of Bern · Tests: Fluoxetine, Sertraline Pill, Friendship Bench Intervention- Problem Solving Therapy
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