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30 recruiting trials

for Metabolic Dysfunction-Associated Liver Disease

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a1 site๐Ÿ“ Sioux Falls Sanford Health Diet and Meal Timing in Patients With Metabolic Dysfunction Associated Steatoic Liver Disease NCT05332613NA1 site๐Ÿ“ New York Weill Medical College of Cornell University ยท Tests: TRE plus SOC, SOC, TRE Metabolic Features Effects on FAST Score in MASLD Patients NCT06867419n/a1 site๐Ÿ“ Tanta Tanta University ยท Tests: Transient Elastography A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH NCT06419374Phase 3330 sites๐Ÿ“ Birmingham๐Ÿ“ Homewood๐Ÿ“ Chandler Hoffmann-La Roche ยท Tests: Pegozafermin, Placebo Digoxin In NASH (CODIN) NCT06588699Phase 22 sites๐Ÿ“ New Haven๐Ÿ“ New Haven Yale University ยท Tests: Digoxin, Placebo Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease NCT07058155Phase 41 site๐Ÿ“ Cleveland The Cleveland Clinic ยท Tests: Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect), โ€ฆ A Single-Dose Pharmacokinetic Study of HRS-4729 Injection in Healthy Participants and Patients With Renal Impairment NCT07807059Phase 11 site๐Ÿ“ Chengdu Fujian Shengdi Pharmaceutical Co., Ltd. ยท Tests: HRS-4729 Corazones Unidos Study NCT07298213NA1 site๐Ÿ“ Tucson University of Arizona ยท Tests: Your Heart, Your Health Spleen Stiffness Measurement for the Detection of Advanced Fibrosis NCT07440511n/a1 site๐Ÿ“ Rome Fondazione Policlinico Universitario Agostino Gemelli IRCCS Targeting the Skeletal Muscle to Treat Metabolic Dysfunction-associated Steatotic Liver Disease NCT06506513NA2 sites๐Ÿ“ Brussels๐Ÿ“ Louvain-la-Neuve Cliniques universitaires Saint-Luc- Universitรฉ Catholique dโ€ฆ ยท Tests: High-intensity interval training, Moderate intensity exercise training, Low intensity exercise training A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD NCT07527910Phase 29 sites๐Ÿ“ Tucson๐Ÿ“ Coronado๐Ÿ“ Pasadena Regeneron Pharmaceuticals ยท Tests: ALN-PNP, Tirzepatide, Placebo A Phase 3 Study Evaluating the Safety and Efficacy of HSK31679 in Patients With MASH NCT07581951Phase 31 site๐Ÿ“ Beijing Haisco Pharmaceutical Group Co., Ltd. ยท Tests: HSK31679, Placebo Cardiovascular Risk Assessment and Coronary Calcium Score in Thai MASLD Patients NCT07865936n/a1 site๐Ÿ“ Bangkok Watcharasak Chotiyaputta Impact of Steatotic Liver Disease Associated With Metabolic Dysfunction (MASLD) on Frailty, Cognition, and Quality of Life. A Gender-sensitive Approach Towards a Comprehensive and Equitable Perspective. NCT07652892n/a2 sites๐Ÿ“ Barcelona๐Ÿ“ Barcelona Fundaciรณ Institut de Recerca de l'Hospital de la Santa Creuโ€ฆ Advanced Fibrosis Detection for MASLD in Primary Care NCT07159386NA1 site๐Ÿ“ Charleston Medical University of South Carolina ยท Tests: EHR alert Synbiotics Impact on Insulin and TNF-ฮฑ in MAFLD: a Gut Microbiota Profile Analysis NCT06585982NA1 site๐Ÿ“ Semarang Universitas Diponegoro ยท Tests: Treatment, Control Fructose is a Metabolic and Inflammatory Pathogenic Factor in Metabolic Dysfunction-associated Steatohepatitis (MASH) NCT07013916NA2 sites๐Ÿ“ London๐Ÿ“ London Queen Mary University of London ยท Tests: fructose, glucose A Large Language Model-based Chatbot for Alcohol Reduction in Patients With Metabolic Alcohol-Related Liver Disease NCT07450144NA1 site๐Ÿ“ Hong Kong The University of Hong Kong ยท Tests: LLM-based chatbot, Telephone counseling, Alcohol Brief Intervention Management Concepts of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) Among Chinese Physicians NCT07682363n/a1 site๐Ÿ“ Beijing Novo Nordisk A/S ยท Tests: No treatment is given A Study of Efimosfermin Alfa in Adults With Hepatic Impairment NCT07358546Phase 13 sites๐Ÿ“ Rialto๐Ÿ“ Tampa๐Ÿ“ San Antonio GlaxoSmithKline ยท Tests: Efimosfermin alfa Diagnostic Value of the Liver Inflammation Index for MASH in Patients With T2DM and MAFLD NCT07632677n/a22 sites๐Ÿ“ Bengbu๐Ÿ“ Hefei๐Ÿ“ Wuhu The Affiliated Nanjing Drum Tower Hospital of Nanjing Univeโ€ฆ ยท Tests: iLivTouch (Vibration-controlled transient elastography) A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis) NCT06318169Phase 3370 sites๐Ÿ“ Birmingham๐Ÿ“ Chandler๐Ÿ“ Flagstaff Hoffmann-La Roche ยท Tests: Pegozafermin, Placebo Endohepatology-Based Reclassification of Treatment Indication in High-Risk MASLD NCT07877272n/a1 site๐Ÿ“ Mรผnster University Hospital Muenster ยท Tests: Non-invasive MASLD and portal hypertension assessment, Single-session endohepatology assessment Pediatric Metabolic Dysfunction-associated Steatotic Liver Disease and Food Insecurity NCT07090083n/a1 site๐Ÿ“ San Francisco University of California, San Francisco Dietary Glycine Supplementation in Metabolic Dysfunction-associated Steatotic Liver Disease NCT07285135NA1 site๐Ÿ“ Singapore Singapore General Hospital ยท Tests: Glycine, Placebo Type 2 DIAbeTes With NAFLD: innOvative Biomarkers of Disease progressioN and clInical outComes NCT06567990NA4 sites๐Ÿ“ Dijon๐Ÿ“ Lyon๐Ÿ“ Nantes Hospices Civils de Lyon ยท Tests: Non-invasive test for the screening of MASLD-related advanced fibrosis in patients with T2D. Study of PNPLA3 Genetic Polymorphisms in Patients With Non-Alcoholic Fatty Liver Disease in an Ultramarine Population (AdipoDROMExpo) NCT07330830n/a3 sites๐Ÿ“ Cayenne๐Ÿ“ Pointe-ร -Pitre๐Ÿ“ Saint-Denis Centre Hospitalier Universitaire de la Guadeloupe The Effects of Tai Chi on Metabolic Dysfunction-associated Fatty Liver Disease in Middle-Aged and Older Adults NCT06717828NA1 site๐Ÿ“ Fuzhou Fujian Provincial Hospital ยท Tests: Tai Chi Exercise, Regular Exercise, Control Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial NCT07193927Phase 21 site๐Ÿ“ Girona AB Biotics, SA ยท Tests: Lactiplantibacillus plantarum Probiotic Mixture, Placebo comparator containing maltodextrin Time-restricted Feeding in MASLD NCT07530809NA1 site๐Ÿ“ Homburg Universitรคt des Saarlandes ยท Tests: time-restricted feeding in a 5:2 regimen
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