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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metabolic Dysfunction-Associated Steatotic Liver Disease

Metabolic Features Effects on FAST Score in MASLD Patients NCT06867419n/a1 site📍 Tanta Tanta University · Tests: Transient Elastography A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH NCT06419374Phase 3330 sites📍 Birmingham📍 Homewood📍 Chandler Hoffmann-La Roche · Tests: Pegozafermin, Placebo Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease NCT07058155Phase 41 site📍 Cleveland The Cleveland Clinic · Tests: Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect), … A Single-Dose Pharmacokinetic Study of HRS-4729 Injection in Healthy Participants and Patients With Renal Impairment NCT07807059Phase 11 site📍 Chengdu Fujian Shengdi Pharmaceutical Co., Ltd. · Tests: HRS-4729 Corazones Unidos Study NCT07298213NA1 site📍 Tucson University of Arizona · Tests: Your Heart, Your Health Spleen Stiffness Measurement for the Detection of Advanced Fibrosis NCT07440511n/a1 site📍 Rome Fondazione Policlinico Universitario Agostino Gemelli IRCCS Targeting the Skeletal Muscle to Treat Metabolic Dysfunction-associated Steatotic Liver Disease NCT06506513NA2 sites📍 Brussels📍 Louvain-la-Neuve Cliniques universitaires Saint-Luc- Université Catholique d… · Tests: High-intensity interval training, Moderate intensity exercise training, Low intensity exercise training A Phase 2a Study of ALN-PNP With and Without a GLP1R Agonist in Adult Patients With Homozygous PNPLA3-Related MASLD NCT07527910Phase 29 sites📍 Tucson📍 Coronado📍 Pasadena Regeneron Pharmaceuticals · Tests: ALN-PNP, Tirzepatide, Placebo Cardiovascular Risk Assessment and Coronary Calcium Score in Thai MASLD Patients NCT07865936n/a1 site📍 Bangkok Watcharasak Chotiyaputta Impact of Steatotic Liver Disease Associated With Metabolic Dysfunction (MASLD) on Frailty, Cognition, and Quality of Life. A Gender-sensitive Approach Towards a Comprehensive and Equitable Perspective. NCT07652892n/a2 sites📍 Barcelona📍 Barcelona Fundació Institut de Recerca de l'Hospital de la Santa Creu… Advanced Fibrosis Detection for MASLD in Primary Care NCT07159386NA1 site📍 Charleston Medical University of South Carolina · Tests: EHR alert A Large Language Model-based Chatbot for Alcohol Reduction in Patients With Metabolic Alcohol-Related Liver Disease NCT07450144NA1 site📍 Hong Kong The University of Hong Kong · Tests: LLM-based chatbot, Telephone counseling, Alcohol Brief Intervention Management Concepts of Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) Among Chinese Physicians NCT07682363n/a1 site📍 Beijing Novo Nordisk A/S · Tests: No treatment is given A Study of Efimosfermin Alfa in Adults With Hepatic Impairment NCT07358546Phase 13 sites📍 Rialto📍 Tampa📍 San Antonio GlaxoSmithKline · Tests: Efimosfermin alfa A Study Evaluating the Efficacy and Safety of Pegozafermin in Participants With MASH and Fibrosis (ENLIGHTEN-Fibrosis) NCT06318169Phase 3370 sites📍 Birmingham📍 Chandler📍 Flagstaff Hoffmann-La Roche · Tests: Pegozafermin, Placebo Endohepatology-Based Reclassification of Treatment Indication in High-Risk MASLD NCT07877272n/a1 site📍 Münster University Hospital Muenster · Tests: Non-invasive MASLD and portal hypertension assessment, Single-session endohepatology assessment Pediatric Metabolic Dysfunction-associated Steatotic Liver Disease and Food Insecurity NCT07090083n/a1 site📍 San Francisco University of California, San Francisco Dietary Glycine Supplementation in Metabolic Dysfunction-associated Steatotic Liver Disease NCT07285135NA1 site📍 Singapore Singapore General Hospital · Tests: Glycine, Placebo Study of PNPLA3 Genetic Polymorphisms in Patients With Non-Alcoholic Fatty Liver Disease in an Ultramarine Population (AdipoDROMExpo) NCT07330830n/a3 sites📍 Cayenne📍 Pointe-à-Pitre📍 Saint-Denis Centre Hospitalier Universitaire de la Guadeloupe Investigation of the Efficacy of a Probiotic Mixture in Moderate Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD): A Mechanistic Trial NCT07193927Phase 21 site📍 Girona AB Biotics, SA · Tests: Lactiplantibacillus plantarum Probiotic Mixture, Placebo comparator containing maltodextrin Time-restricted Feeding in MASLD NCT07530809NA1 site📍 Homburg Universität des Saarlandes · Tests: time-restricted feeding in a 5:2 regimen Effect of Insulin Lowering on Lipogenesis NCT07403604Phase 11 site📍 New York Columbia University · Tests: Placebo, Diazoxide Oral Suspension, 2 mg per kg per dose, Deuterated water (2H2O/D2O), 70%, Insulin Suppression Test (I… Effect of Ketone Esters on Liver Fat Content and Metabolic Function NCT07097506Phase 21 site📍 St Louis Washington University School of Medicine · Tests: bis-octanoyl (R)-1,3-butanediol (C8 ketone di-ester), Placebo Food Insecurity and MASLD: A Fruit and Vegetable Intervention Study NCT07091539NA1 site📍 San Francisco University of California, San Francisco · Tests: Fruit/vegetable vouchers Rehabilitation With Exercise-Based Intervention for Nonalcoholic Chronic Hepatic Esteatosis NCT07552727NA1 site📍 Valdivia Universidad San Sebastián · Tests: High-intensity interval training Study to Evaluate ALN-CIDEB in Adults With Fibrotic Metabolic Dysfunction-Associated Steatohepatitis (MASH) NCT07631637Phase 216 sites📍 Tucson📍 Tucson📍 Tucson Regeneron Pharmaceuticals · Tests: ALN-CIDEB, Placebo Efficacy of 12-week Daytime Restricted Eating on Hepatic Steatosis of Obesity NCT07378072NA9 sites📍 Angers📍 Bordeaux📍 Dijon Nantes University Hospital · Tests: Time Restricted Eating, Usual care only A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With Cirrhosis NCT06461208Phase 323 sites📍 Basildon📍 Bournemouth📍 Bristol King's College London · Tests: Encapsulated FMT, Placebo Digital Early Warning System for Acute Lung Injury in Liver Surgery NCT07070362n/a4 sites📍 Beijing📍 Beijing📍 Chongqing Beijing Tsinghua Chang Gung Hospital Cardiac Dysfunction in Patients with Fatty Liver Disease NCT06386094n/a1 site📍 Chandigarh Post Graduate Institute of Medical Education and Research, … · Tests: Echocardiographic assessment
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