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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Biliary Tract Carcinoma

AB122 Platform Study NCT04999761Phase 19 sites๐Ÿ“ Aichi๐Ÿ“ Chiba๐Ÿ“ Ehime Taiho Pharmaceutical Co., Ltd. ยท Tests: AB122, AB122, TAS-116, TAS-120, TAS-115 A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) NCT06330064Phase 1, Phase 2120 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Whittier Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors NCT06043466Phase 12 sites๐Ÿ“ Hangzhou๐Ÿ“ Hangzhou Chongqing Precision Biotech Co., Ltd ยท Tests: CEA-targeted CAR-T cells CTX-009 With Gemcitabine, Cisplatin, and Durvalumab as First-line Therapy in Patients With Unresectable or Metastatic Biliary Tract Cancers NCT06548412Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Gemcitabine, Cisplatin, Durvalumab, CTX-009 Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors NCT06975410Phase 1, Phase 24 sites๐Ÿ“ Seoul๐Ÿ“ Seoul๐Ÿ“ Seoul Yuhan Corporation ยท Tests: YH32364 Trastuzumab Plus Chemotherapy vs Chemotherapy Alone in First-line HER2 Positive Advanced Biliary Tract Cancer Patients NCT07062263Phase 36 sites๐Ÿ“ Muzaffarpur๐Ÿ“ Mumbai๐Ÿ“ Bhubaneswar Tata Memorial Centre ยท Tests: Trastuzumab, Chemotherapy Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib in Advanced HER2-Positive/Low-Expression Biliary Tract Cancer NCT07704177Phase 21 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: Trastuzumab Rezetecan, Adebrelimab, Lenvatinib Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors NCT04900818Phase 121 sites๐Ÿ“ Orange๐Ÿ“ Aurora๐Ÿ“ Layfayette I-Mab Biopharma US Limited ยท Tests: TJ033721 (givastomig), TJ033721 (givastomig) , nivolumab, chemotherapy, TJ033721 (givastomig), chemotherapy, TJ033721 (โ€ฆ Dual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract Cancer NCT07641036Phase 1, Phase 21 site๐Ÿ“ Shenzhen Beijing Biotech ยท Tests: EB-HC01 dual-target CARNK cells, Fludarabine, Cyclophosphamide A Phase 1 Dose Escalation and Dose Expansion Trial of KST-6051 in Participants With Advanced Solid Tumors With Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Mutation NCT07458347Phase 19 sites๐Ÿ“ Los Angeles๐Ÿ“ Sarasota๐Ÿ“ Tampa Kestrel Therapeutics, Inc. ยท Tests: KST-6051, Gemcitabine/nab-paclitaxel, Cetuximab, Pembrolizumab, mFOLFOX6 A Study of BL-M07D1 Versus Physician's Choice of Chemotherapy in Patients With HER2-expressing Locally Advanced or Metastatic Biliary Tract Cancer After Platinum-containing Chemotherapy Failure NCT07606599Phase 32 sites๐Ÿ“ Hefei๐Ÿ“ Beijing Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-M07D1, Oxaliplatin, Calcium levofolinate, Fluorouracil, Irinotecan Hydrochloride Liposome Pressurized Intraperitoneal Aerosolized Nab-Paclitaxel in Combination With Gemcitabine and Cisplatin for the Treatment of Biliary Tract Cancer Patients With Peritoneal Metastases NCT05285358Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Cisplatin, Gemcitabine, Nab-paclitaxel, Quality-of-Life Assessment, Questionnaire Administration Determination of Copper and Other Trace Elements in Serum Samples From Patients With Biliary Tract Cancers NCT06060990NA1 site๐Ÿ“ Ljubljana Institute of Oncology Ljubljana ยท Tests: trace elements Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC NCT05733598Phase 212 sites๐Ÿ“ Beverly Hills๐Ÿ“ La Jolla๐Ÿ“ Miami Replimune, Inc. ยท Tests: RP2, Bevacizumab, Atezolizumab, Durvalumab, RP2 Monotherapy CDH17 CAR-T Therapy in Advanced Malignant Solid Tumors NCT06937567EARLY Phase 11 site๐Ÿ“ Hangzhou Zhejiang University ยท Tests: CDH17 CAR-T, FAST LACO-Stim CDH17 CAR-T A Study of TQB2102 for Injection in the Treatment of HER2-positive Biliary Tract Cancer NCT06431490Phase 1, Phase 243 sites๐Ÿ“ Fuyang๐Ÿ“ Hefei๐Ÿ“ Hefei Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharโ€ฆ ยท Tests: TQB2102 for injection A Phase I/IIa Study of AZD8205 Given Alone or Combined, in Participants With Advanced/Metastatic Solid Malignancies NCT05123482Phase 1, Phase 267 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ Santa Monica AstraZeneca ยท Tests: AZD8205, AZD8205 and AZD2936 (Rilvegostomig), AZD8205 and AZD5305 (saruparib), AZD8205 and AZD5305 (saruparib) and AZD2โ€ฆ A Phase 1/2a Study of DB-1303/BNT323 in Advanced/Metastatic Solid Tumors NCT05150691Phase 1, Phase 2102 sites๐Ÿ“ Cerritos๐Ÿ“ Los Angeles๐Ÿ“ San Diego DualityBio Inc. ยท Tests: DB-1303/BNT323, Pertuzumab Injection, Ritonavir, Itraconazole Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio NCT05655949Phase 21 site๐Ÿ“ Boston Beth Israel Deaconess Medical Center ยท Tests: Gemcitabine, Cisplatin, Durvalumab, Yttrium-90 This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors NCT06451497Phase 13 sites๐Ÿ“ Boston๐Ÿ“ Austin, TX 78758๐Ÿ“ San Antonio Zumutor Biologics Inc. ยท Tests: ZM008 A Phase 1/1B Study of ST-01156, a Small Molecule RBM39 Degrader, in Patients With Advanced Solid Malignancies NCT07197554Phase 16 sites๐Ÿ“ Duarte๐Ÿ“ Newport Beach๐Ÿ“ Boston SEED Therapeutics, Inc. ยท Tests: ST-01156 Morning Versus Afternoon Administration of Immunotherapy for the Treatment of Advanced or Metastatic Solid Tumors, The Knight SHIFT Study NCT07405086Phase 41 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Biospecimen Collection, Immune Checkpoint Inhibitor Phase II Study of Trastuzumab Rezetecan Combined With Adebrelimab and Lenvatinib as First-Line Therapy for Advanced HER2-Positive/HER2-Low Biliary Tract Cancer NCT07670273Phase 21 site๐Ÿ“ Beijing Peking Union Medical College Hospital ยท Tests: Trastuzumab Rezetecan, Adebrelimab, Lenvatinib PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma NCT05286814Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Dexamethasone, PDS01ADC, Intera 3000 Hepatic Artery Infusion Pump (HAIP), Floxuridine Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma NCT07780838Phase 21 site๐Ÿ“ Columbus Ohio State University Comprehensive Cancer Center ยท Tests: Biospecimen Collection, Cisplatin, Computed Tomography, Durvalumab, Gemcitabine AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001) NCT07038343Phase 1, Phase 227 sites๐Ÿ“ Gilbert๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Avenzo Therapeutics, Inc. ยท Tests: AVZO-1418, Combination Agent 1, Combination Agent 2 A Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid Tumors NCT07020221Phase 1, Phase 220 sites๐Ÿ“ Los Angeles๐Ÿ“ Baltimore๐Ÿ“ Boston Verastem, Inc. ยท Tests: VS-7375, Cetuximab, Carboplatin + Pemetrexed + Pembrolizumab, Gemcitabine + Nab-paclitaxel, Pembrolizumab Adebrelimab Combined With Gemcitabine, Cisplatin, and Simvastatin for Advanced Biliary Tract Cancer NCT07392541Phase 1, Phase 21 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: Adebrelimab, Gemcitabine + Cisplatin, Simvastatin 20mg BMS-986504 in Combination With Pemetrexed for the Treatment of Metastatic Solid Tumors With MTAP Deletion NCT07594626Phase 1, Phase 21 site๐Ÿ“ Chicago Northwestern University ยท Tests: Biospecimen Collection, Computed Tomography, Pemetrexed, PRMT5 Inhibitor BMS-986504 A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors NCT05592626Phase 1, Phase 219 sites๐Ÿ“ Sacramento๐Ÿ“ Celebration๐Ÿ“ Miami Marengo Therapeutics, Inc. ยท Tests: STAR0602, Irinotecan (Camptosar), Docetaxel (Taxotere)
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