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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Castration-Resistant Prostate Cancer Patients

Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan NCT06099093Phase 42 sites๐Ÿ“ Boston๐Ÿ“ Boston Brigham and Women's Hospital ยท Tests: 18F-DCFPyl The COSMYC Trial (COmbined Suppression of MYC) NCT06922318Phase 21 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: ZEN-3694, Testosterone cypionate, Enzalutamide, Luteinizing hormone-releasing hormone (LHRH) analogue A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer NCT06609005Phase 1, Phase 222 sites๐Ÿ“ Scottsdale๐Ÿ“ Newport Beach๐Ÿ“ Orange Shenzhen Ionova Life Sciences Co., Ltd. ยท Tests: INV-9956 Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors NCT07288359Phase 1, Phase 216 sites๐Ÿ“ Atlanta๐Ÿ“ Nashville๐Ÿ“ San Antonio Novartis Pharmaceuticals ยท Tests: GVV858, Fulvestrant, Letrozole ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer NCT04986423Phase 231 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ Whittier Zenith Epigenetics ยท Tests: ZEN003694, Enzalutamide Kidney Function and Risk Factors in Patients with Metastatic Castration-Resistant Prostate Cancer (mCRPC) Undergoing 177Lutetium-PSMA Radioligand Therapy: a Prospective Observational Study - KiRi-Trial NCT06720532n/a1 site๐Ÿ“ Munich Hannah Schaefer ยท Tests: characterization of renal function., Handgrip strength test, Questionaires A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1) NCT07723248Phase 312 sites๐Ÿ“ Coral Springs๐Ÿ“ Jeffersonville๐Ÿ“ Holland ORIC Pharmaceuticals ยท Tests: Rinzimetostat, Darolutamide, Enzalutamide, Docetaxel An Observational Study to Learn More About the Safety of Darolutamide in Men With Prostate Cancer in Korea NCT06334120n/a1 site๐Ÿ“ Multiple Locations Bayer ยท Tests: Darolutamide (Nubeqa, BAY1841788) Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer NCT06236139Phase 1, Phase 21 site๐Ÿ“ Seattle Fred Hutchinson Cancer Center ยท Tests: Anti-STEAP1 CAR T-cells, Biopsy Procedure, Biospecimen Collection, Bone Scan, Computed Tomography Carboplatin or Olaparib for BRcA Deficient Prostate Cancer NCT04038502Phase 218 sites๐Ÿ“ West Los Angeles๐Ÿ“ Aurora๐Ÿ“ Washington D.C. VA Office of Research and Development ยท Tests: Carboplatin, Olaparib A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer NCT06457919Phase 1, Phase 212 sites๐Ÿ“ New Haven๐Ÿ“ Basking Ridge๐Ÿ“ Middletown Memorial Sloan Kettering Cancer Center ยท Tests: Tinengotinib, abiraterone acetate with prednisone, Enzalutamide A Study of Real-World Characteristics, Treatment Patterns, and Outcomes Among mCRPC Patients Previously Treated With an Androgen Receptor Pathway Inhibitor, Taxane-Based Chemotherapy, and Lutetium-177 Vipivotide Tetraxetan NCT07677267n/a1 site๐Ÿ“ East Hanover Novartis Pharmaceuticals ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate Cancer NCT03903835Phase 332 sites๐Ÿ“ Aalst๐Ÿ“ Antwerp๐Ÿ“ Bruges Karolinska Institutet ยท Tests: Enzalutamide Oral Capsule, Abiraterone Oral Tablet, Carboplatin, Cabazitaxel 60 mg Solution for Injection, Docetaxel Inโ€ฆ A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer NCT07570979Phase 113 sites๐Ÿ“ Boston๐Ÿ“ Dallas๐Ÿ“ Melbourne Novartis Pharmaceuticals ยท Tests: INR731, Enzalutamide, Abiraterone, Androgen deprivation therapy (ADT) Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer NCT06059118Phase 21 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: DFMO, testosterone cypionate, Luteinizing hormone-releasing hormone (LHRH) analogue, Enzalutamide A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer NCT07287150Phase 248 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ Iowa City Hoffmann-La Roche ยท Tests: Inavolisib, Enzalutamide, Abiraterone, Docetaxel A Study of TRC003 in the Treatment of Patients With Progressive PSMA-positive mCRPC NCT07567521Phase 1, Phase 22 sites๐Ÿ“ Taiyuan๐Ÿ“ Shanghai C Ray Therapeutics ยท Tests: Radiopharmaceuticals Cabazitaxel +/- Carboplatin vs 177Lu-PSMA-617 in Metastatic Castrate-resistant Prostate Cancer NCT06738303Phase 21 site๐Ÿ“ Cleveland Case Comprehensive Cancer Center ยท Tests: Cabazitaxel and carboplatin, Lu-PSMA-617 GI-102 (CD80-IgG4 Fc-IL2v3) in Combination With Pasritamig in Patients With Metastatic Castration-resistant Prostate Cancer (mCRPC) (JET-201) NCT07871435Phase 1, Phase 26 sites๐Ÿ“ New York๐Ÿ“ Seoul๐Ÿ“ Seoul GI Innovation, Inc. ยท Tests: GI-102, Pasritamig A Study of [225Ac]Ac-AKY-2519 in Patients With B7-H3 Expressing Solid Tumors NCT07887971Phase 11 site๐Ÿ“ Miami Aktis Oncology, Inc. ยท Tests: [225Ac]Ac-AKY-2519 (therapeutic), [64Cu]Cu-AKY-2519 (imaging) A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors NCT03972657Phase 1, Phase 224 sites๐Ÿ“ Gilbert๐Ÿ“ Phoenix๐Ÿ“ Tucson Regeneron Pharmaceuticals ยท Tests: REGN5678, Cemiplimab A Study of SYNC-T Therapy SV-102 in Participants With Metastatic Castration-Resistant Prostate Cancer NCT06533644Phase 223 sites๐Ÿ“ Phoenix๐Ÿ“ Tucson๐Ÿ“ Little Rock Syncromune, Inc. ยท Tests: Partial Oncolysis, SV-102 A Trial to Find Out if REGN4336 is Safe and How Well it Works Alone and in Combination With REGN5678 for Adult Participants With Advanced Prostate Cancer NCT05125016Phase 1, Phase 214 sites๐Ÿ“ Palo Alto๐Ÿ“ New Haven๐Ÿ“ Louisville Regeneron Pharmaceuticals ยท Tests: REGN4336, REGN5678 Green Tea and Quercetin in Combination With Docetaxel Chemotherapy in Castration-resistant Prostate Cancer Patients NCT06615752Phase 1, Phase 21 site๐Ÿ“ Los Angeles Charles Drew University of Medicine and Science ยท Tests: green tea and quercetin + docetaxel, Placebo + docetaxel A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide NCT06844383Phase 28 sites๐Ÿ“ Duarte๐Ÿ“ La Jolla๐Ÿ“ Boston Prostate Cancer Clinical Trials Consortium ยท Tests: Talazoparib with enzalutamide, Talazoparib Pembrolizumab Plus 177Lu-PSMA-617 in Patients With Castration Resistant Prostate Cancer NCT05766371Phase 21 site๐Ÿ“ San Francisco University of California, San Francisco ยท Tests: Pembrolizumab, 177Lu-PSMA-617 A Trial Evaluating the Efficacy and Safety of HC-1119 Soft Capsules in Patients with Metastatic Castration-Resistant Prostate Cancer (mCRPC). NCT03851640Phase 31 site๐Ÿ“ Shanghai Hinova Pharmaceuticals Inc. ยท Tests: HC-1119, placebo A Phase I Clinical Study of HLX3902 in Patients With mCRPC and Other Advanced Tumours NCT07533708Phase 15 sites๐Ÿ“ Nanchang๐Ÿ“ Naning๐Ÿ“ Nanjing Shanghai Henlius Biotech ยท Tests: HLX3902 Lutetium (177Lu) DGUL Combined With Pembrolizumab in Metastatic Castration-Resistant Prostate Cancer NCT07244393Phase 11 site๐Ÿ“ Seoul Cellbion Co., Ltd. ยท Tests: Lutetium (177Lu) DGUL, Pembrolizumab 177^Lu-PSMA-617 in Combination With Sipuleucel-T for the Treatment of Metastatic Castration-Resistant Prostate Cancer NCT07219147Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biospecimen Collection, Bone Scan, Computed Tomography, Leukapheresis, Lutetium Lu 177 Vipivotide Tetraxetan
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