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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Gastric Adenocarcinoma

Radiotherapy + Chemoimmunotherapy Followed by Surgery in Patients With Limited Metastatic Gastric or GEJ Cancer NCT06121700Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Radiotherapy targeted to the primary lesion, Radiotherapy targeted to the metastatic lesions, Anti-PD-1 monoclonal antiโ€ฆ Ph1b/2 Study of the Safety and Efficacy of SHR-A1811 Combinations in Advanced HER2 Expression Gastric Cancer NCT05671822Phase 21 site๐Ÿ“ Shanghai Suzhou Suncadia Biopharmaceuticals Co., Ltd. ยท Tests: SHR-A1811 and SHR-1701, SHR-A1811 and capecitabine, SHR-A181, SHR-1701, and capecitabine, SHR-A1811, SHR-1316, and capeโ€ฆ AB122 Platform Study NCT04999761Phase 19 sites๐Ÿ“ Aichi๐Ÿ“ Chiba๐Ÿ“ Ehime Taiho Pharmaceutical Co., Ltd. ยท Tests: AB122, AB122, TAS-116, TAS-120, TAS-115 Phase II RAINSPOT: Zolbetuximab-Paclitaxel-Ramucirumab for CLDN18.2 Positive Gastro-esophageal Cancer NCT06962137Phase 26 sites๐Ÿ“ Antwerp๐Ÿ“ Brussels๐Ÿ“ Brussels Universitaire Ziekenhuizen KU Leuven ยท Tests: zolbetuximab, Retrospective cohort, no intervention A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) NCT06330064Phase 1, Phase 2120 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Whittier Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer. NCT06902545n/a15 sites๐Ÿ“ Goyang-si๐Ÿ“ Suwon๐Ÿ“ Suwon Astellas Pharma Korea, Inc. ยท Tests: zolbetuximab Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers NCT04221893NA2 sites๐Ÿ“ San Francisco๐Ÿ“ Walnut Creek University of California, San Francisco ยท Tests: Radiation Therapy (RT) SHR-1701 Combined With Chemotherapy for Gastric or Gastroesophageal Junction Adenocarcinoma With Peritoneal Metastasis NCT07384234Phase 22 sites๐Ÿ“ Shanghai๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: SHR-1701, Capecitabine, S-1, Paclitaxel, Oxaliplatin A Study to Investigate Tislelizumab Administered as Subcutaneous Injection Versus Intravenous Infusion Plus Chemotherapy in Patients With Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma NCT07043400Phase 395 sites๐Ÿ“ Chandler๐Ÿ“ Los Alamitos๐Ÿ“ Colorado Springs BeOne Medicines ยท Tests: Subcutaneous Tislelizumab, Intravenous Tislelizumab, Cisplatin, Leucovorin, 5-fluorouracil (5-FU) First-line Treatment With RC48 Plus Sintilimab and S-1 in Advanced Gastric Cancer (RCTS2) NCT06730373Phase 220 sites๐Ÿ“ Zhengzhou๐Ÿ“ Binzhou๐Ÿ“ Dongying Qilu Hospital of Shandong University ยท Tests: Disitamab Vedotin, Sintilimab, S-1, Trastuzumab, Oxaliplatin Assessing Iparomlimab and Tuvonralimab in Recurrent or Metastatic MSI-H/dMMR Gastric Cancer NCT07127822Phase 210 sites๐Ÿ“ Shijiazhuang๐Ÿ“ Harbin๐Ÿ“ Zhengzhou Peking University ยท Tests: Iparomlimab and Tuvonralimab, First line chemotherapy plus PD-1/PD-L1 antibody A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors NCT07115043Phase 1, Phase 213 sites๐Ÿ“ Grand Rapids๐Ÿ“ St Louis๐Ÿ“ Pittsburgh AstraZeneca ยท Tests: AZD6750, rilvegostomig SHR-A1904 Compared With Investigator's Choice of Therapy in Claudin18.2 Positive Patitens With Second-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma NCT06649292Phase 31 site๐Ÿ“ Guangzhou Shanghai Hengrui Pharmaceutical Co., Ltd. ยท Tests: SHR-A1904, Paclitaxel, Docetaxel, Irinotecan TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Stomach and Esophageal Cancer NCT06532799Phase 1, Phase 21 site๐Ÿ“ Beijing Essen Biotech ยท Tests: Tumor Infiltrating Lymphocytes (TIL), Cyclophosphamid, Fludarabine, Interleukin-2, Pembrolizumab Study of TJ033721 (Givastomig) in Subjects With Advanced or Metastatic Solid Tumors NCT04900818Phase 121 sites๐Ÿ“ Orange๐Ÿ“ Aurora๐Ÿ“ Layfayette I-Mab Biopharma US Limited ยท Tests: TJ033721 (givastomig), TJ033721 (givastomig) , nivolumab, chemotherapy, TJ033721 (givastomig), chemotherapy, TJ033721 (โ€ฆ LM-302 and S-1 Plus Intraperitoneal Paclitaxel With or Without Cadonilimab for Claudin 18.2-positive Gastric or Gastroesophageal Junction Adenocarcinoma With Peritoneal Metastasis: a Prospective, Exploratory Study NCT07556640Phase 21 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: LM-302, S-1, paclitaxel, LM-302, Cadonilimab, S-1, paclitaxel mFOLFIRINOX Versus mFOLFOX With or Without Nivolumab for the Treatment of Advanced, Unresectable, or Metastatic HER2 Negative Esophageal, Gastroesophageal Junction, and Gastric Adenocarcinoma NCT05677490Phase 3798 sites๐Ÿ“ Birmingham๐Ÿ“ Anchorage๐Ÿ“ Anchorage Alliance for Clinical Trials in Oncology ยท Tests: Fluorouracil, Leucovorin Calcium, Oxaliplatin, Irinotecan, Nivolumab Synergistic Effects of PD-1 Antibody and Chemotherapy/Targeted Therapy Followed by Surgery-centric Local Treatment in Patients With Limited-metastatic Gastric Cancer NCT06468280Phase 22 sites๐Ÿ“ Shanghai๐Ÿ“ Shanghai Shanghai Zhongshan Hospital ยท Tests: Local treatment (Surgical), PD-1 Monoclonal Antibody, XELOX/SOX Chemotherapy Regimen, Local Treatment (Non-surgical), Tโ€ฆ A Study of Zolbetuximab Together With Pembrolizumab and Chemotherapy in Adults With Gastric Cancer NCT06901531Phase 3252 sites๐Ÿ“ Birmingham๐Ÿ“ Bakersfield๐Ÿ“ Cerritos Astellas Pharma Global Development, Inc. ยท Tests: zolbetuximab, Pembrolizumab, Capecitabine, Oxaliplatin, Folinic acid (leucovorin or local equivalent) Capeox Regimen Combined With Sintilimab and Bevacizumab for Gastric Cancer NCT05640609Phase 1, Phase 21 site๐Ÿ“ Chengdu West China Hospital ยท Tests: Capeox regimen combined with Sintilimab and Bevacizumab Lenvatinib in Combination With Nivolumab Plus Chemotherapy in Metastatic Gastric Cancer Patients With Malignant Ascites NCT07149090Phase 1, Phase 21 site๐Ÿ“ Seoul Asan Medical Center ยท Tests: Lenvatinib A Phase Ib/II Study of ATG-022 Plus Pembrolizumab With/Without Chemotherapy in Participants With Claudin (CLDN) 18.2-positive, HER2-negative, Unresectable or Metastatic Gastric or Gastroesophageal Junction AdenocarcinomaUnresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma NCT07327229Phase 1, Phase 230 sites๐Ÿ“ Hefei๐Ÿ“ Hefei๐Ÿ“ Beijing Antengene Biologics Limited ยท Tests: ATG-022, pembrolizumab/KEYTRUDAยฎ, CAPOX SHR-A1811 for Subjects With Her2-positive Gastric Cancer and Gastroesophageal Junction Adenocarcinoma After Progression on or After First-line Anti-HER2 Therapy-containing Regimen NCT06123494Phase 31 site๐Ÿ“ Shanghai Jiangsu HengRui Medicine Co., Ltd. ยท Tests: SHR-A1811, Ramucirumab / Paclitaxel/ Docetaxel/ Irinotecan Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 17 sites๐Ÿ“ Denver๐Ÿ“ Grand Rapids๐Ÿ“ St Louis Duboce Biopharmaceuticals, Inc. ยท Tests: DBC-664 Chemoradiotherapy and SHR-1701 in Patients With Unresectable Gastric Cancer NCT07689851Phase 23 sites๐Ÿ“ Shenzhen๐Ÿ“ Taiyuan๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: COPOX, Radiotherapy, SHR-1701 AVA6103 in Subjects With Locally Advanced or Metastatic Selected Solid Tumors NCT07454642Phase 17 sites๐Ÿ“ Scottsdale๐Ÿ“ Sarasota๐Ÿ“ Chicago Avacta Life Sciences Ltd ยท Tests: AVA6103 A Study to Learn About the Study Medicine Called PF-08098488 in People With Advanced Solid Tumors. NCT07903415Phase 12 sites๐Ÿ“ Grand Rapids๐Ÿ“ San Antonio Pfizer ยท Tests: PF-08098488 IN10018 With Nab-Paclitaxel and Cadonilimab for Metastatic or Recurrent Gastric-Type Cervical Adenocarcinoma: Phase 2 Trial NCT06654011Phase 22 sites๐Ÿ“ Wuhan๐Ÿ“ Xiangyang Union Hospital, Tongji Medical College, Huazhong Universityโ€ฆ ยท Tests: IN10018, Nab-paclitaxel, Cadonilimab Study of AZD5863 in Adult Participants With Advanced or Metastatic Solid Tumors NCT06005493Phase 1, Phase 225 sites๐Ÿ“ Jacksonville๐Ÿ“ Rochester๐Ÿ“ New York AstraZeneca ยท Tests: AZD5863, AZD2936
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