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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Hepatocellular Carcinoma

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC NCT06553885Phase 21 site๐Ÿ“ Tampa H. Lee Moffitt Cancer Center and Research Institute ยท Tests: Enfortumab Vedotin Standard Versus Radiobiologically-Guided Dose Selected SBRT in Liver Cancer NCT04745390NA1 site๐Ÿ“ London London Health Sciences Centre Research Institute OR Lawson โ€ฆ ยท Tests: Radiation therapy A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) NCT06330064Phase 1, Phase 2120 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Whittier Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers NCT04221893NA2 sites๐Ÿ“ San Francisco๐Ÿ“ Walnut Creek University of California, San Francisco ยท Tests: Radiation Therapy (RT) Radioembolization With Intra-arterial Angiotensin II to Improve Tumor-absorbed Dose (RADIANT) NCT07312292Phase 21 site๐Ÿ“ Utrecht Niek Wijnen ยท Tests: Angiotensin II (Giaprezaยฎ), Yttrium-90 radioembolization Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein ฮฒ-Catenin, The SAPHIRE Trial NCT06811116Phase 1, Phase 24 sites๐Ÿ“ Irvine๐Ÿ“ Orange๐Ÿ“ Portland National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Cabozantinib S-malate, Imaging Procedure, Sapanisertib A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites๐Ÿ“ Aurora๐Ÿ“ Lake Mary๐Ÿ“ Lebanon 7 Hills Pharma, LLC ยท Tests: Alintegimod, Ipilimumab, Nivolumab A Study to Evaluate the Efficacy and Safety of IBI310 and Sintilimab Combination Therapy in Patients With Hepatocellular Carcinoma as First-line Treatment. NCT07490262Phase 2, Phase 32 sites๐Ÿ“ Hefei๐Ÿ“ Shanghai Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. ยท Tests: Bevacizumab, Capecitabine, Oxaliplatin, IBI310, Sintilimab Mts105 for Advanced Hepatocellular Carcinoma NCT06689540Phase 11 site๐Ÿ“ Beijing Shen Lin ยท Tests: MTS105 A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma NCT05440708Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ La Jolla๐Ÿ“ Los Angeles Tvardi Therapeutics, Incorporated ยท Tests: TTI-101, Pembrolizumab, Atezolizumab, Bevacizumab Holmium-166 Transarterial Radioembolization for the Treatment of Hepatocellular Carcinoma NCT06873269n/a1 site๐Ÿ“ Brussels Universitair Ziekenhuis Brussel ยท Tests: Baseline assessment, holmium-166 radioembolization, Follow-up phase Sapu003 in Advanced mTOR-sensitive Solid Tumors NCT07369505Phase 11 site๐Ÿ“ Adelaide SAPU NANO (US) LLC ยท Tests: Sapu003, Exemestane 25 MG A Study of AK104+Lenvatinib in Combination With Transarterial Chemoembolization (TACE) Versus TACE in Participants With Incurable/Non-metastatic Hepatocellular Carcinoma NCT06371157Phase 34 sites๐Ÿ“ Zhengzhou๐Ÿ“ Changsha๐Ÿ“ Nanjing Akeso ยท Tests: AK104, Lenvatinib, TACE, Placebo for AK104, Placebo for Lenvatinib Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform NCT06349642n/a3 sites๐Ÿ“ Phoenix๐Ÿ“ Jacksonville๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biospecimen Collection, Tissue Collection Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration A Phase II Clinical Study to Evaluate HLX43 in Patients With Locally Advanced or Metastatic HCC Failed or Intolerance to Standard Therapy NCT06742892Phase 21 site๐Ÿ“ Hunan Shanghai Henlius Biotech ยท Tests: HLX43 DOSE 1, HLX43 DOSE 2, HLX43 DOSE 3 The Safety, Efficacy, and Immune Response of Multimodal Thermal Therapy in the Treatment of Malignant Liver Tumors NCT07159048NA1 site๐Ÿ“ Shanghai Fudan University ยท Tests: Multimodal Tumor Thermal Therapy System, Radiofrequency Ablation System or Microwave Ablation System A Study to Explore the Reasonable Dosage and Evaluate the Efficacy, Safety and Tolerability of HLX10 and HLX04 with or Without HLX53 in Untreated, Locally Advanced or Metastatic Hepatocellular Carcinoma Patients. NCT06349980Phase 21 site๐Ÿ“ Shanghai Shanghai Henlius Biotech ยท Tests: HLX53 (1000mg), HLX53 (2000mg), HLX10, HLX04, Placebo Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma NCT06582017Phase 111 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Nammi Therapeutics Inc ยท Tests: QXL138AM Injection every 2 weeks by IV Infusion Phase I Study of Tumor Treating Fields (TTF) in Combination With Cabozantinib or With Pembrolizumab and Nab-Paclitaxel in Patients With Advanced Solid Tumors Involving the Abdomen or Thorax NCT05092373Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Atezolizumab, Cabozantinib S-malate, Nab-paclitaxel, Tumor Treating Fields Therapy A Phase 1 Study of TGI-5 as Monotherapy and in Combination With Nivolumab in Subjects With Locally Advanced/Metastatic Solid Tumors NCT07376707Phase 11 site๐Ÿ“ Shanghai Hefei TG ImmunoPharma Co., Ltd. ยท Tests: TGI-5 Study of RP2 in Combination With Second-line Therapy in Patients With Locally Advanced or Metastatic HCC NCT05733598Phase 212 sites๐Ÿ“ Beverly Hills๐Ÿ“ La Jolla๐Ÿ“ Miami Replimune, Inc. ยท Tests: RP2, Bevacizumab, Atezolizumab, Durvalumab, RP2 Monotherapy Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases NCT05248581n/a1 site๐Ÿ“ Rochester University of Rochester ยท Tests: Liver transplantation A Study of MGC026 in Participants With Advanced Solid Tumors NCT06242470Phase 112 sites๐Ÿ“ Los Angeles๐Ÿ“ Grand Rapids๐Ÿ“ Lake Success MacroGenics ยท Tests: MGC026 Dose Escalation, MGC026 Dose for Expansion, Pembrollizumab, vobramitamab tavatecan ctDNA Monitoring in Patients With HCC and mCRC NCT07001085NA1 site๐Ÿ“ Warsaw Medical University of Warsaw ยท Tests: Tumor Tissue Collection and NGS, Blood Collection for Plasma ctDNA, ctDNA Mutation Analysis via ddPCR Italian Group of Regenerative and Occlusive Worldwide-used Techniques of Hepatic Hypertrophy NCT07445412n/a1 site๐Ÿ“ Bologna IRCCS Azienda Ospedaliero-Universitaria di Bologna DB-1311 in Combination With BNT327 or DB-1305 in Advanced/Metastatic Solid Tumors NCT06953089Phase 237 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Wheat Ridge DualityBio Inc. ยท Tests: DB-1311/BNT324, BNT327, DB-1305/BNT325 Liquid Biopsy for Hepatocellular Carcinoma Molecular Characterization After Y90 NCT07303712n/a1 site๐Ÿ“ Palo Alto Palo Alto Veterans Institute for Research Intravital Microscopy in Human Solid Tumors NCT03823144NA1 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Diagnostic Microscopy, Fluorescein Sodium Injection Short Stitch Versus Traditional Suture for the Prevention of Incisional Hernia After Open Hepatectomy NCT04982653Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Quality-of-Life Assessment, Surgical Procedure, Surgical Procedure
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