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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Metastatic Malignant Neoplasm in the Brain

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) NCT04427384n/a54 sites📍 Phoenix📍 Little Rock📍 Castro Valley GT Medical Technologies, Inc. · Tests: GammaTile NK Cell Therapy for Malignant Solid Brain Tumors NCT07552233NA4 sites📍 Beijing📍 Qinhuangdao📍 Zhengzhou Peking University Third Hospital · Tests: Autologous NK cells Sensitivity of Organoids to Predict Treatment Outcome in Breast Cancer Metastases NCT06468124n/a2 sites📍 London📍 London King's College London A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain NCT05419076Phase 27 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Stereotactic Radiosurgery, Cerebrospinal fluid collection Study on the Treatment of HER2-negative Breast Cancer Brain Metastases With Radiotherapy Combined With Anlotinib NCT07396454Phase 21 site📍 Nanjing The First Affiliated Hospital with Nanjing Medical Universi… · Tests: Radiotherapy Combined with Anlotinib and a Microtubule Inhibitor Frameless Stereotactic Radiosurgery for Intact Brain Metastases NCT02747303Phase 21 site📍 Chicago University of Chicago · Tests: Stereotactic Radiosurgery SRS & Abemaciclib w/wo Imlunestrant in the Management of HR+/HER2- Breast CA Brain Metastases NCT04923542Phase 1, Phase 22 sites📍 Tampa📍 Columbus H. Lee Moffitt Cancer Center and Research Institute · Tests: Stereotactic Radiosurgery (SRS), Abemaciclib, Endocrine therapy Reducing the Incidence of Symptomatic Brain Metastases With MRI Surveillance NCT05692635Phase 21 site📍 Winston-Salem Wake Forest University Health Sciences · Tests: MRI of the Brain, Blood draws, Quality of Life Questionnaires, Gadolinium TY-9591 in the Patients With EGFR Mutations in Advanced NSCLC With Brain Metastases NCT05948813Phase 21 site📍 Beijing TYK Medicines, Inc · Tests: TY-9591, Osimertinib Assessment of Eloquent Function in Brain Tumor Patients NCT01535430n/a1 site📍 Omaha University of Nebraska · Tests: Brain mapping Developing a New MRI Technique to Understand Changes in Brain Tumors After Treatment NCT05559853n/a1 site📍 New York Memorial Sloan Kettering Cancer Center · Tests: CEST-MRF A Phase II Study of Nivolumab With Ipilimumab and Cabozantinib in Patients With Untreated Renal Cell Carcinoma Brain Metastases NCT05048212Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Nivolumab, Ipilimumab, Cabozantinib Phase I Study of Fractionated Stereotactic Radiation Therapy NCT03726359NA1 site📍 The Bronx Albert Einstein College of Medicine · Tests: Fractionated Stereotactic Radiation Therapy (FSRT) A Phase IIa Study to Evaluate NBQ72S NCT06810804Phase 21 site📍 Beijing Nantong Bencao Quadriga Medical Technology Co. Ltd. · Tests: NBQ72S Blood-brain Barrier (BBB) Opening Using Exablate Focused Ultrasound With Standard of Care Treatment of NSCLC Brain Mets NCT05317858Phase 316 sites📍 Phoenix📍 Newport Beach📍 Fort Lauderdale InSightec · Tests: Blood Brain Barrier Opening - Oncology, Pembrolizumab, Atezolizumab, Cemiplimab, Nivolumab A Study to Evaluate the Efficacy of Osimertinib With Early Intervention SRS Treatment Compared to the Continuation of Osimertinib Alone, in Patients With EGFR Mutated NSCLC and Asymptomatic Brain Metastases NCT05033691NA1 site📍 Jerusalem Hadassah Medical Organization · Tests: Stereotactic surgery Nitroglycerin Plus Radiotherapy Versus Conventional Radiotherapy in Patients With Lung Cancer. NCT06238882NA1 site📍 Mexico City Instituto Nacional de Cancerologia de Mexico · Tests: Nitroglycerin Stereotactic Radiation for Growing/Changing Brain Metastases With Same-Day Radiation Planning and Treatment With Margin Reduction NCT07132190Phase 21 site📍 Boston Ayal A. Aizer, MD · Tests: Linear accelerator-based stereotactic radiation for brain metastases using 0mm or 1mm PTV Stereotactic Radiosurgery Dose Escalation for Brain Metastases NCT02390518Phase 11 site📍 Salt Lake City University of Utah · Tests: Stereotactic Radiosurgery ASL in Brain Metastasis MRI Following Gamma Knife Treatment NCT04833335NA1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: MRI perfusion sequence RO7771950 Versus Tucatinib in Combination With Trastuzumab and Capecitabine in People With Locally Advanced or Metastatic Breast Cancer That is Human Epidermal Growth Factor Receptor 2 (HER2)-Positive NCT07413939Phase 2, Phase 3206 sites📍 Huntsville📍 Gilbert📍 San Francisco Hoffmann-La Roche · Tests: RO7771950, Tucatinib, Trastuzumab, Capecitabine Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery NCT03184038NA2 sites📍 Sewell📍 Philadelphia Sidney Kimmel Comprehensive Cancer Center at Thomas Jeffers… · Tests: Cognitive Assessment, Stereotactic Radiosurgery, Stereotactic Body Radiation Therapy, Quality-of-Life Assessment ioMRI in the Surgery of Brain Metastases. NCT07197632NA1 site📍 Munich Technical University of Munich · Tests: Surgery with intraoperative MRI Contribution of the CEST Sequence in the Characterization of Radionecrosis of Brain Metastases of Pulmonary Origin NCT05977803NA1 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: MRI with CEST sequence, IVIM and ASL sequence Phase II Study of Nivolumab in Combination With Relatlimab in Patients With Active Melanoma Brain Metastases NCT05704647Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: BMS-986213 (Relatlimab-Nivolumab FDC), Nivolumab, Relatlimab Immunotherapy or Targeted Therapy With or Without Stereotactic Radiosurgery for Patients With Brain Metastases From Melanoma or Non-small Cell Lung Cancer NCT05522660Phase 315 sites📍 Naples📍 Padova📍 Perugia ETOP IBCSG Partners Foundation · Tests: Stereotactic radiosurgery, Immune checkpoint inhibitor Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer NCT05386108Phase 1, Phase 286 sites📍 Fullerton📍 Los Angeles📍 Urbana Stemline Therapeutics, Inc. · Tests: Elacestrant, Abemaciclib Bevacizumab Versus Corticosteroids as First-line Treatment in Patients With Symptomatic Cerebral Radiation Necrosis After Radiation for High-grade Glioma or Brain Metastases NCT06888817Phase 36 sites📍 Amsterdam📍 Amsterdam📍 Leiden The Netherlands Cancer Institute · Tests: Bevacizumab, Dexamethasone Study of SHR-A1811 in HER2-expression Advanced Breast Cancer With Brain Metastases NCT05769010Phase 21 site📍 Zhengzhou Henan Cancer Hospital · Tests: SHR-A1811, Pyrotinib, Bevacizumab, Adebelizumab A Brain Metastases Research Platform to Tackle the Challenge of CNS Metastases in Solid Tumours NCT04109131NA17 sites📍 Anderlecht📍 Brussels📍 Brussels Jules Bordet Institute · Tests: Samples collection: Plasma, Samples collection: CSF, Samples collection: Non-CNS Metastatic Tumour Tissue, Brain MRI, S…
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