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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Malignant Neoplasm in the Liver

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease NCT06607458Phase 220 sites๐Ÿ“ Duarte๐Ÿ“ Santa Monica๐Ÿ“ Miami Delcath Systems Inc. ยท Tests: Melphalan/HDS Followed by Consolidation Treatment with Trifluridine-tipiracil plus Bevacizumab, Trifluridine-tipiracil โ€ฆ Advanced Therapies for Liver Metastases NCT04622423n/a1 site๐Ÿ“ Milan IRCCS San Raffaele Multimodal Prehabilitation During Chemotherapy in Patients With Colorectal Liver Metastases NCT04520737NA1 site๐Ÿ“ Tarragona Institut Investigacio Sanitaria Pere Virgili ยท Tests: Physical Prehabilitation A Study on the Efficacy and Safety of Multi-mode Ablation Combined With Systemic Therapy in the Treatment of CRCLM NCT06590259Phase 21 site๐Ÿ“ Shanghai Shanghai 6th People's Hospital ยท Tests: Multi-mode tumor treatment system, Sintilimab+mFOLFOX6 or FOLFIRI+bevacizumab or cetuximab Standard Versus Radiobiologically-Guided Dose Selected SBRT in Liver Cancer NCT04745390NA1 site๐Ÿ“ London London Health Sciences Centre Research Institute OR Lawson โ€ฆ ยท Tests: Radiation therapy A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) NCT06330064Phase 1, Phase 2120 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Whittier Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers NCT04221893NA2 sites๐Ÿ“ San Francisco๐Ÿ“ Walnut Creek University of California, San Francisco ยท Tests: Radiation Therapy (RT) Tebentafusp-tebn With LDT in Metastatic UM NCT06626516Phase 1, Phase 21 site๐Ÿ“ Philadelphia Thomas Jefferson University ยท Tests: Tebentafusp-Tebn, GM-CSF (Sargramostim), BCNU MRE for Assessment of Histopathological Growth Patterns in Colorectal Liver Metastases NCT06208397n/a1 site๐Ÿ“ Shenyang Shengjing Hospital ยท Tests: Magnetic Resonance Elastography and routine MRI FMT+ QL1706+Bevacizumab+ XELOX as First-line Treatment for Advanced MSS-type Colorectal Cancer With Liver Metastasis NCT06801665Phase 21 site๐Ÿ“ Changzhou Hua Jiang ยท Tests: FMT+QL1706+Bevacizumab+XELOX PULSAR Combined With PD-1 Ab and Chemotherapy Plus Bev. for CRLM NCT06788171Phase 21 site๐Ÿ“ Fuzhou Fujian Cancer Hospital ยท Tests: Personalized Ultrafractionated Stereotactic Adaptive Radiotherapy, Bevacizumab, Capecitabine, Oxaliplatin, Sintilimab TRANsplantation vs reSECTion After Conversion Therapy for Initially Unresectable Colorectal Liver Metastases NCT07607873NA1 site๐Ÿ“ Milan Niguarda Hospital ยท Tests: Liver Transplantation, Liver Resection plus Ablation Testing the Addition of an Anti-cancer Drug, Sapanisertib, to the Usual Chemotherapy Treatment (Cabozantinib) in Metastatic Liver Cell Cancer With a Change in Genes for the Protein ฮฒ-Catenin, The SAPHIRE Trial NCT06811116Phase 1, Phase 24 sites๐Ÿ“ Irvine๐Ÿ“ Orange๐Ÿ“ Portland National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Cabozantinib S-malate, Imaging Procedure, Sapanisertib REGULUS: MRI-guided Adaptive SABR for Liver Cancers NCT07223307Phase 21 site๐Ÿ“ Palo Alto Stanford University ยท Tests: MRI-guided adaptive stereotactic ablative body radiotherapy (SABR) Assessment of Liver Diseases Using a Deep-Learning Approach Based on Ultrasound RF-Data NCT06317181NA4 sites๐Ÿ“ Dresden๐Ÿ“ Dresden๐Ÿ“ Halle Technische Universitรคt Dresden ยท Tests: Collection of elastography data, Collection of ultrasonic raw data A Study of Oral 7HP349 (Alintegimod) in Combination With Ipilimumab Followed by Nivolumab Monotherapy NCT06362369Phase 1, Phase 25 sites๐Ÿ“ Aurora๐Ÿ“ Lake Mary๐Ÿ“ Lebanon 7 Hills Pharma, LLC ยท Tests: Alintegimod, Ipilimumab, Nivolumab Exosome-derived Extrahepatic Metastasis Detection By Liquid Biopsy In Colorectal Cancer Liver Metastases NCT07224724n/a1 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: EXELION Colorectal Metastasis to Liver Extraction With Auxiliary Transplant and Delayed Resection NCT06698146n/a1 site๐Ÿ“ Chicago Northwestern University Ivonescimab Plus Chemotherapy in Patients With Initially Unresectable Colorectal Cancer Liver Metastases NCT06848842Phase 21 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ ยท Tests: Ivonescimab plus chemotherapy A Study to Evaluate the Efficacy and Safety of IBI310 and Sintilimab Combination Therapy in Patients With Hepatocellular Carcinoma as First-line Treatment. NCT07490262Phase 2, Phase 32 sites๐Ÿ“ Hefei๐Ÿ“ Shanghai Innovent Biopharmaceutical Technology (Hangzhou) Co., LTD. ยท Tests: Bevacizumab, Capecitabine, Oxaliplatin, IBI310, Sintilimab A Phase 1 Trial of ERX-315 in Participants With Advanced Solid Tumors NCT06533332Phase 15 sites๐Ÿ“ Ryde๐Ÿ“ Sydney๐Ÿ“ Westmead EtiraRx Australia Pty Ltd ยท Tests: ERX-315 Cemiplimab and Transarterial Radioembolization With Y-90 SIR-S Spheres for the Treatment of Liver Directed Metastatic Breast Cancer NCT06860815Phase 21 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biopsy, Biospecimen Collection, Cemiplimab, Computed Tomography, Magnetic Resonance Imaging Platform Study of Immunotherapy Combinations in Colorectal Cancer Liver Metastases NCT06300463Phase 21 site๐Ÿ“ New York Weill Medical College of Cornell University ยท Tests: Botensilimab, Balstilimab, AGEN1423, Radiation HepQuant: Study to Assess the Role of Blood-based Biomarkers and Quantitative MR Imaging for Patients Receiving Radiation Therapy for Liver Cancer NCT06899152NA1 site๐Ÿ“ The Bronx Montefiore Medical Center ยท Tests: HepQuant DuO, Multiparametric MRI Scans A Study of TTI-101 as Monotherapy and in Combination in Participants With Locally Advanced or Metastatic, and Unresectable Hepatocellular Carcinoma NCT05440708Phase 1, Phase 221 sites๐Ÿ“ Birmingham๐Ÿ“ La Jolla๐Ÿ“ Los Angeles Tvardi Therapeutics, Incorporated ยท Tests: TTI-101, Pembrolizumab, Atezolizumab, Bevacizumab Hepzato Kit and Opdualag for Metastatic Melanoma and Liver Metastasis NCT07281924Phase 1, Phase 21 site๐Ÿ“ Madison University of Wisconsin, Madison ยท Tests: Nivolumab and Relatlimab, Melphalan The DRAGON 2 Trial NCT05428735NA24 sites๐Ÿ“ New Haven๐Ÿ“ Clayton๐Ÿ“ Vienna Maastricht University ยท Tests: Embolization Preoperative Ketogenic Diet for Reduction of Hepatic Steatosis NCT05884723NA1 site๐Ÿ“ London Anton Skaro ยท Tests: Ketogenic Diet FOLFOX-HAIC as Conversion Treatment for Initially Unresectable Colorectal Liver Metastasis NCT06988852Phase 21 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: FOLFOX (oxaliplatin, leucovorin, 5-fluorouracil [5FU]), hepatic arterial infusion chemotherapy (HAIC), Bevacizumab, Cetโ€ฆ OAR-Based, Dose Escalated SBRT With Real Time Adaptive MRI Guidance for Liver Metastases NCT04020276NA1 site๐Ÿ“ Madison University of Wisconsin, Madison ยท Tests: SBRT
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