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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Prostate Adenocarcinoma

Standard Systemic Therapy With or Without Definitive Treatment in Treating Participants With Metastatic Prostate Cancer NCT03678025Phase 3338 sites📍 Gilbert📍 Phoenix📍 Phoenix SWOG Cancer Research Network · Tests: Abiraterone, Bicalutamide, Degarelix, Docetaxel, Flutamide Imaging of Solid Tumors Using 18F-TRX NCT06942104Phase 11 site📍 San Francisco Rahul Aggarwal · Tests: 18F-TRX, Positron Emission Tomography (PET)/Computerized tomography (CT), Tumor Biopsy, Blood Specimen Collection Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: SX-682, DTX Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer NCT06236139Phase 1, Phase 21 site📍 Seattle Fred Hutchinson Cancer Center · Tests: Anti-STEAP1 CAR T-cells, Biopsy Procedure, Biospecimen Collection, Bone Scan, Computed Tomography Talazoparib With Androgen Deprivation Therapy and Abiraterone for the Treatment of Castration Sensitive Prostate Cancer NCT04734730Phase 21 site📍 Duarte City of Hope Medical Center · Tests: Abiraterone Acetate, Bicalutamide, Degarelix, Goserelin Acetate, Leuprolide Acetate Testing the Safety and Effectiveness of Radiation-based Treatment (Lutetium Lu 177 Dotatate) for Metastatic Prostate Cancer That Has Neuroendocrine Cells NCT05691465Phase 213 sites📍 Duarte📍 Los Angeles📍 Los Angeles National Cancer Institute (NCI) · Tests: Biospecimen Collection, Computed Tomography, Gallium Ga 68-DOTATATE, Lutetium Lu 177 Dotatate, Positron Emission Tomogr… Dual-target PSMA/PSCA CAR-NK Cells in Advanced Prostate Cancer NCT07641049Phase 11 site📍 Shenzhen Beijing Biotech · Tests: ETB-DualNK-01, Fludarabine, Cyclophosphamide Docetaxel to Androgen Receptor Pathway Inhibitors in Patients With Metastatic Castration Sensitive Prostate Cancer and Suboptimal PSA Response NCT06592924Phase 3395 sites📍 Anchorage📍 Anchorage📍 Anchorage Canadian Cancer Trials Group · Tests: Abiraterone, Enzalutamide, Apalutamide, Darolutamide (BAY 1841788), Docetaxel Study of DCC-2812 in Participants With Advanced Genitourinary Cancers NCT06966024Phase 18 sites📍 Boston📍 Ann Arbor📍 St Louis Deciphera Pharmaceuticals, LLC · Tests: DCC-2812 A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for Adult Participants With Metastatic Castration-Resistant Prostate Cancer and Other Tumors NCT03972657Phase 1, Phase 224 sites📍 Gilbert📍 Phoenix📍 Tucson Regeneron Pharmaceuticals · Tests: REGN5678, Cemiplimab A Study of Talazoparib With or Without Enzalutamide in People With Prostate Cancer Who Have Previously Received Abiraterone Acetate or Darolutamide NCT06844383Phase 28 sites📍 Duarte📍 La Jolla📍 Boston Prostate Cancer Clinical Trials Consortium · Tests: Talazoparib with enzalutamide, Talazoparib Measuring Oncological Value of Exercise and Statin NCT05796973Phase 31 site📍 Tampere Tampere University Hospital · Tests: Guided physical exercise, Atorvastatin, Independent exercise Study of the Epidemiological, Clinical, Diagnostic, and Therapeutic Characteristics of Prostate Cancers in Algeria NCT07484971n/a24 sites📍 Adrar📍 Adrar📍 Algiers Société Algérienne de Formation et Recherche en Oncologie A Study of DS9051b in Participants With Advanced or Metastatic Adrenocortical Carcinoma and Metastatic Castration-resistant Prostate Cancer NCT07189403Phase 16 sites📍 Sarasota📍 New York📍 Providence Daiichi Sankyo · Tests: DS9051b Treating Prostate Cancer That Has Come Back After Surgery With Apalutamide and Targeted Radiation Based on PET Imaging NCT04423211Phase 3341 sites📍 Anchorage📍 Anchorage📍 Anchorage ECOG-ACRIN Cancer Research Group · Tests: 3-Dimensional Conformal Radiation Therapy, Apalutamide, Computed Tomography, Degarelix, External Beam Radiation Therapy Sacituzumab Tirumotecan in Combination With Tagitanlimab in the Treatment of Aggressive Variant Prostate Cancer (AVPC) and Neuroendocrine Prostate Cancer (NEPC) NCT07179783Phase 21 site📍 Tianjin Tianjin Medical University Second Hospital · Tests: Sacituzumab Tirumotecan, Tagitanlimab 177^Lu-PSMA-617 in Combination With Sipuleucel-T for the Treatment of Metastatic Castration-Resistant Prostate Cancer NCT07219147Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Biospecimen Collection, Bone Scan, Computed Tomography, Leukapheresis, Lutetium Lu 177 Vipivotide Tetraxetan Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma NCT06582017Phase 111 sites📍 Los Angeles📍 Los Angeles📍 Los Angeles Nammi Therapeutics Inc · Tests: QXL138AM Injection every 2 weeks by IV Infusion A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer NCT07192614Phase 1, Phase 226 sites📍 Orlando📍 Tampa📍 Boston AstraZeneca · Tests: AZD6621 Testing the Effectiveness of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) With One Anti-cancer Targeted Drug (Cabozantinib) for Rare Genitourinary Tumors NCT03866382Phase 2582 sites📍 Birmingham📍 Anchorage📍 Anchorage National Cancer Institute (NCI) · Tests: Biospecimen Collection, Bone Scan, Cabozantinib S-malate, Computed Tomography, Echocardiography Test A Study of MGC026 in Participants With Advanced Solid Tumors NCT06242470Phase 112 sites📍 Los Angeles📍 Grand Rapids📍 Lake Success MacroGenics · Tests: MGC026 Dose Escalation, MGC026 Dose for Expansion, Pembrollizumab, vobramitamab tavatecan Supraphysiological Androgen to Enhance Treatment Activity in Metastatic Castration-Resistant Prostate Cancer, SPECTRA Study NCT06039371Phase 21 site📍 Seattle University of Washington · Tests: Biopsy Procedure, Biospecimen Collection, Bone Scan, Carboplatin, Computed Tomography Cryoablation Combined With Stereotactic Body Radiation Therapy for the Treatment of Painful Bone Metastases, the CROME Trial NCT04693377NA1 site📍 Houston M.D. Anderson Cancer Center · Tests: Cryosurgery, Quality-of-Life Assessment, Stereotactic Body Radiation Therapy Ruxolitinib and Enzalutamide for the Treatment of Metastatic Castration-Resistant Prostate Cancer NCT06616155Phase 1, Phase 23 sites📍 Chicago📍 Ann Arbor📍 Detroit University of Michigan Rogel Cancer Center · Tests: Biopsy, Biospecimen Collection, Bone Scan, Computed Tomography, Enzalutamide This is a Phase 1 Trial of ZM008, an Anti-LLT1 Antibody, Used as Single Agent Followed by Combination Treatment With Toripalimab in Patients With Advanced Solid Tumors NCT06451497Phase 13 sites📍 Boston📍 Austin, TX 78758📍 San Antonio Zumutor Biologics Inc. · Tests: ZM008 LUtetium-177 DOsimetry as a Predictive Biomarker of Response in Metastatic Prostate Cancer Patients Treated With PSMA Radioligand THerapy. NCT07370597n/a1 site📍 Brussels Jules Bordet Institute Measuring Circulating Tumor Deoxyribonucleic Acid Tumor Fraction to Guide Early 177Lu-PSMA-617 Treatment Discontinuation in Patients With Metastatic Castration-Resistant Prostate Cancer, DYNAMO Trial NCT07698535Phase 21 site📍 Seattle University of Washington · Tests: Lutetium Lu 177 Vipivotide Tetraxetan, Cell-free Circulating Tumor DNA Assay, Computed Tomography, Docetaxel, PSMA PET … The Impact of Metastatic Directed Radiotherapy (MDRT) on Oligoprogressive Castration Resistant Prostate Cancer (CRPC) NCT07038304Phase 22 sites📍 Groningen📍 Nijmegen University Medical Center Groningen · Tests: Metastasis directed radiotherapy Clinical Application of the J-PET Scanner Prototype NCT06242119n/a1 site📍 Krakow Jagiellonian University · Tests: J-PET scan Study of PSMA-targeted Therapy and Androgen Receptor Suppression in Low-volume Metastatic ProstatE Cancer: SPARKLE Trial NCT07650240Phase 21 site📍 Rochester Mayo Clinic · Tests: Abiraterone Acetate, Biospecimen Collection, Leuprolide Acetate, Lutetium Lu 177 Vipivotide Tetraxetan, Prednisone
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