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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Metastatic Urothelial Carcinoma

A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) NCT06330064Phase 1, Phase 2120 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Whittier Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan A Study of BL-B01D1 + PD-1 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma NCT06405425Phase 21 site๐Ÿ“ Shanghai Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1, PD-1 Pembrolizumab Maintenance After Enfortumab Vedotin (EV)/Pembro Induction in Front-Line Metastatic Urothelial Carcinoma NCT07221942Phase 21 site๐Ÿ“ Philadelphia Fox Chase Cancer Center ยท Tests: Enfortumab vedotin, Pembrolizumab A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ San Francisco Nurix Therapeutics, Inc. ยท Tests: NX-1607, Paclitaxel Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors NCT06975410Phase 1, Phase 24 sites๐Ÿ“ Seoul๐Ÿ“ Seoul๐Ÿ“ Seoul Yuhan Corporation ยท Tests: YH32364 Phase II Study of Trastuzumab Rezetecan or in Combination With Adebrelimab in HER2-Expressing Locally Advanced or Metastatic Urothelial Carcinoma (la/mUC) NCT07241793Phase 26 sites๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Adebrelimab, Trastuzumab Rezetecan A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors NCT06465069Phase 139 sites๐Ÿ“ Duarte๐Ÿ“ La Jolla๐Ÿ“ Los Angeles Eli Lilly and Company ยท Tests: LY4052031, Pembrolizumab An Investigation of Kidney and Urothelial Tumor Metabolism in Patients Undergoing Surgical Resection and/or Biopsy NCT04623502NA1 site๐Ÿ“ Dallas University of Texas Southwestern Medical Center ยท Tests: 13C-Glucose, 13C-Acetate, 13C-Lactate, 13C-Glutamine, 13C-Fructose 9MW2821 + Toripalimab vs 9MW2821 for 1st Line Locally Advanced or Metastatic Urothelial Carcinoma NCT06823427Phase 22 sites๐Ÿ“ Changsha๐Ÿ“ Nanjing Mabwell (Shanghai) Bioscience Co., Ltd. ยท Tests: 9MW2821, Toripalimab (JS001 ) Study of DCC-2812 in Participants With Advanced Genitourinary Cancers NCT06966024Phase 18 sites๐Ÿ“ Boston๐Ÿ“ Ann Arbor๐Ÿ“ St Louis Deciphera Pharmaceuticals, LLC ยท Tests: DCC-2812 Pembrolizumab Plus CA-4948 for the Treatment of Patients With Progressive Metastatic Urothelial Cancer Despite Prior Immunotherapy NCT06439836Phase 111 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ La Jolla National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Emavusertib, Magnetic Resonance Imaging Study of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rฮฑ Binding, in Patients With Unresectable Locally Advanced or Metastatic Cancer NCT05267626Phase 1, Phase 217 sites๐Ÿ“ Miami๐Ÿ“ Grand Rapids๐Ÿ“ Minneapolis Aulos Bioscience, Inc. ยท Tests: AU-007, Aldesleukin, Avelumab, Nivolumab A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract NCT07218380Phase 3276 sites๐Ÿ“ Tucson๐Ÿ“ Little Rock๐Ÿ“ Irvine Eli Lilly and Company ยท Tests: Vepugratinib, Placebo, EV, Pembrolizumab Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform NCT06349642n/a3 sites๐Ÿ“ Phoenix๐Ÿ“ Jacksonville๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biospecimen Collection, Tissue Collection DBC-664 in Adult Patients With Solid Tumors NCT07705035Phase 17 sites๐Ÿ“ Denver๐Ÿ“ Grand Rapids๐Ÿ“ St Louis Duboce Biopharmaceuticals, Inc. ยท Tests: DBC-664 Modular Trial of sEphB4-HSA in EphrinB2-High Solid Tumors NCT06493552Phase 2, Phase 31 site๐Ÿ“ Santa Monica Vasgene Therapeutics, Inc ยท Tests: SEphB4-HSA, Pembrolizumab, Gemcitabine, Cisplatin, Enfortumab vedotin A Study of [225Ac]Ac-AKY-1189 in Patients With Solid Tumors NCT07020117Phase 114 sites๐Ÿ“ Duarte๐Ÿ“ Irvine๐Ÿ“ Miami Aktis Oncology, Inc. ยท Tests: [225Ac]Ac-AKY-1189 (therapeutic), [64Cu]Cu-AKY-1189 (imaging) Cabozantinib in Combination With Enfortumab Vedotin for Locally Advanced or Metastatic Urothelial Cancer NCT04878029Phase 11 site๐Ÿ“ Atlanta Emory University ยท Tests: Cabozantinib S-malate, Enfortumab Vedotin, Quality-of-Life Assessment, Questionnaire Administration A Study of Disitamab Vedotin Alone or With Pembrolizumab in Urothelial Cancer That Expresses HER2 NCT04879329Phase 2221 sites๐Ÿ“ Gilbert๐Ÿ“ Gilbert๐Ÿ“ Anaheim Seagen, a wholly owned subsidiary of Pfizer ยท Tests: disitamab vedotin, pembrolizumab Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration A Study of SI-B003 and BL-B01D1+SI-B003 in Patients With Locally Advanced or Metastatic Urothelial Carcinoma and Other Solid Tumors NCT05965856Phase 21 site๐Ÿ“ Shanghai Sichuan Baili Pharmaceutical Co., Ltd. ยท Tests: BL-B01D1, SI-B003 Phase 1 Study of STRO-006 in Adults With Refractory Solid Tumors That Are Recurrent or Metastatic NCT07807345Phase 16 sites๐Ÿ“ Orlando๐Ÿ“ Boston๐Ÿ“ Oklahoma City Sutro Biopharma, Inc. ยท Tests: STRO-006, Pembrolizumab Enfortumab Vedotin and Pembrolizumab With Cystectomy and/or Ureterectomy for Locally Advanced or Metastatic Bladder and Upper Urothelial Tract Cancer, CAST-AI Trial NCT06764095Phase 41 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biospecimen Collection, Computed Tomography, Cystectomy, Enfortumab Vedotin, Local Therapy A Study of 68Gallium PSMA-PET/CT Scans in People With Bladder Cancer or Skin Cancer NCT05562791Phase 17 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: [68Ga]PSMA, PET/CT imaging A Study Comparing the Combination of Pembrolizumab and Sacituzumab Govitecan-hziy Versus Standard of Care in the Treatment of Advanced Urothelial Cancer NCT06524544Phase 3162 sites๐Ÿ“ Phoenix๐Ÿ“ Irvine๐Ÿ“ Orange National Cancer Institute (NCI) ยท Tests: Biospecimen Collection, Carboplatin, Cisplatin, Computed Tomography, Docetaxel A Phase 2 Clinical Study of ABSK061 and ABSK043 NCT06632262Phase 221 sites๐Ÿ“ Guiyang๐Ÿ“ Guiyang๐Ÿ“ Shijiazhuang Abbisko Therapeutics Co, Ltd ยท Tests: ABSK061 + ABSK043, ABSK061+ABSK043 in combination with CAPOX Vesical Imaging-Reporting and Data System (VI-RADS) Followed by Photodynamic Trans-urethral Resection of Bladder Tumours (PDD-TURBT) to Avoid Secondary Resections (Re-TURBT) in Non-Muscle Invasive Bladder Cancers (NMIBCs) NCT05962541Phase 41 site๐Ÿ“ Rome University of Roma La Sapienza ยท Tests: PDD-TURBT with hexaminolevulinate (Hexvixยฎ), Power Led Saphira (TM) Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma NCT06582017Phase 111 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles Nammi Therapeutics Inc ยท Tests: QXL138AM Injection every 2 weeks by IV Infusion KEYMAKER-U04 Substudy 04D: A Clinical Study of New Treatments Given With Enfortumab Vedotin and Pembrolizumab in People With Urothelial Cancer (MK-3475-04D/KEYMAKER-U04) NCT07232602Phase 1, Phase 217 sites๐Ÿ“ San Francisco๐Ÿ“ Chicago๐Ÿ“ New York Merck Sharp & Dohme LLC ยท Tests: MK-3120, EV, Pembrolizumab, Rescue Medication Therapeutic Plasma Exchange With Enfortumab Vedotin and Pembrolizumab for Treatment of Bladder Cancers NCT07087860Phase 21 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Best Practice, Biospecimen Collection, Central Venous Cannula Insertion, Computed Tomography, Enfortumab Vedotin
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