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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Mitochondrial Disorders

Gene Therapy Clinical Trial for the Treatment Of Leber's HereDitary Optic Neuropathy NCT04912843Phase 2, Phase 31 site๐Ÿ“ Beijing Wuhan Neurophth Biotechnology Limited Company ยท Tests: NR082 injection, Sham Injection Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a1 site๐Ÿ“ Sioux Falls Sanford Health Circulating Tumor Mitochondrial DNA (ct-mtDNA) As a Biomarker for Hepatocellular Carcinoma Recurrence Surveillance NCT06653062n/a1 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: Plasma and Tumor Tissue Mitochondrial DNA (mtDNA) Mutation Analysis Drug Repurposing for Mitochondrial Disorders Using iPSCs Derived Neural Cells NCT06967831n/a2 sites๐Ÿ“ Dรผsseldorf๐Ÿ“ Berlin Charite University, Berlin, Germany ยท Tests: skin biopsy, generation of iPSCs, blood drawing, off-label compassionate drug use Phase 1 Trial of Arginine Hydrochloride for the Management of Diabetic Ketoacidosis in Type 2 Diabetes NCT07167693Phase 1, Phase 21 site๐Ÿ“ Detroit David K Carroll ยท Tests: Arginine hydrochloride, Sodium Chloride 0.9% Socio-cognitive and Biological Responses to Maltreatment NCT07101107n/a1 site๐Ÿ“ Innsbruck Medical University Innsbruck KHENERFIN Study: A Trial to Evaluate the Efficacy and Safety of Sonlicromanol in Primary Mitochondrial Diseases NCT06451757Phase 310 sites๐Ÿ“ Boston๐Ÿ“ Cleveland๐Ÿ“ Houston Khondrion BV ยท Tests: Sonlicromanol, Placebo Acute Infection in Mitochondrial Disease: Metabolism, Infection and Immunity NCT04419870n/a1 site๐Ÿ“ Bethesda National Human Genome Research Institute (NHGRI) Efficacy of Stabilometric Platform to Improve Standing Balance in Patients With Friedreich's Ataxia NCT06692296NA1 site๐Ÿ“ Pieve di Soligo IRCCS Eugenio Medea ยท Tests: Balance training over stabilometric platform, Balance training by means of conventional rehabilitation Phase IA and IB Study of AAVrh.10hFXN Gene Therapy for the Cardiomyopathy of Friedreich's Ataxia NCT05302271Phase 11 site๐Ÿ“ New York Weill Medical College of Cornell University ยท Tests: AAVrh.10hFXN, serotype rh.10 adeno-associated virus (AAV) gene transfer vector expressing the cDNA coding for human FXNโ€ฆ The Effects of Low Intensity Endurance Exercise on Improving Mitochondrial Function, Cell Bioelectrical Impedance Phase Angle, Fatigue and Quality of Life in Lung Cancer Patients With Cancer-related Fatigue NCT07806682NA1 site๐Ÿ“ Taipei Taipei Medical University ยท Tests: Low-Intensity Endurance Continuous Exercise, Low-Intensity Endurance Interval Exercise Clinical Course Of Disease In Participants With FA-CM NCT06865482n/a19 sites๐Ÿ“ La Jolla๐Ÿ“ Tampa๐Ÿ“ Indianapolis Lexeo Therapeutics Effects of Eccentric Exercise Training in Patients With COPD NCT06168266NA1 site๐Ÿ“ New Taipei City Fu Jen Catholic University ยท Tests: Eccentric bike, conventional group Evaluate the Safety and Therapeutic Effects of a Single Intravenous Infusion (IV) of Autologous CD34+ Cells Enriched With Allogenic Placenta-derived Mitochondria in Patients With a Diagnosis of Pearson Syndrome (PS) NCT06017869Phase 21 site๐Ÿ“ Ramat Gan Minovia Therapeutics Ltd. ยท Tests: MNV-201 Mitochondrial Disease-associated ImmunoDeficiencies NCT06213103n/a2 sites๐Ÿ“ Bordeaux๐Ÿ“ Toulouse University Hospital, Bordeaux ยท Tests: Patient cohort, Control cohort Impact of Metabolite Supplementation to Restore Mitochondrial Dysfunction During Septic Shock: a Preclinical Study NCT04288635n/a1 site๐Ÿ“ Angers University Hospital, Angers ยท Tests: Whole blood samples Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms NCT05307367NA1 site๐Ÿ“ Copenhagen University of Copenhagen ยท Tests: Exercise training Systemic Biomarkers of Brain Injury From Hyperammonemia NCT04602325n/a1 site๐Ÿ“ Washington D.C. Children's National Research Institute Collection of Blood and Skin Samples From Patients With Primary Mitochondrial Diseases and Healthy Volunteers NCT06474104n/a1 site๐Ÿ“ Ramat Gan Minovia Therapeutics Ltd. Early Diagnosis of Primary Biliary Cholangitis (PBC) in Patients With Positive Anti-Mitochondrial Antibodies (AMA) and Normal Alkaline Phosphatase (ALP) NCT07205874n/a1 site๐Ÿ“ Madrid Hospital Universitario La Paz Clinical Trial in Patients With Barth Syndrome- 4TAZPower NCT07531251Phase 43 sites๐Ÿ“ Needham๐Ÿ“ Calgary๐Ÿ“ Bristol Stealth BioTherapeutics Inc. ยท Tests: Elamipretide, Placebo Adipose Stem Cell Mitochondria Supplementation to Oocytes (ASCENT) NCT07066267NA1 site๐Ÿ“ Colombo Sunkaky Medical Cooperation ยท Tests: Experimental Friedreich Ataxia Nerve Ultrasund NCT07508631n/a1 site๐Ÿ“ Nice Centre Hospitalier Universitaire de Nice ยท Tests: Nerve ultrasound - routine exam Bioenergetic Effect of Pioglitazone in CLD-PH NCT06336798Phase 21 site๐Ÿ“ Atlanta Emory University ยท Tests: Pioglitazone 30mg, Placebo, Labs A Clinical Trial Evaluating the Safety and Efficacy of a New Light Combination Therapy Addressing Intermediate AMD NCT06557369NA1 site๐Ÿ“ Bergamo Oculox Technologies SA ยท Tests: reSEES Hepatic Histopathology in Urea Cycle Disorders NCT04908319n/a2 sites๐Ÿ“ Washington D.C.๐Ÿ“ Houston Baylor College of Medicine Applying pGz in Mitochondrial Disease NCT05569122Phase 11 site๐Ÿ“ Philadelphia Children's Hospital of Philadelphia ยท Tests: Cardiopulmonary Exercise Testing, pGz Bed, Gentle Jogger, Exercise Pedal, Lumasonยฎ contrast agent A Study to Evaluate the MNV-201 in Patients With Low Risk MDS NCT06465160Phase 11 site๐Ÿ“ Jerusalem Minovia Therapeutics Ltd. ยท Tests: MNV-201 (Autologous CD34+ Cells Enriched with allogenic Placenta Derived Mitochondria) A Phase 2 Study to Assess the Effects of SUL-238 on High Energy Phosphates With ยณยนP-MRS in Patients With Early, Untreated Parkinson's Disease NCT07322887Phase 21 site๐Ÿ“ Groningen GEN ฤฐlaรง ve SaฤŸlฤฑk รœrรผnleri A.ลž. ยท Tests: SUL-238 (1500 mg t.i.d.) film-coated tablets, SUL-238 (500 mg t.i.d.) film-coated tablets, Placebo Combating the Diagnostic Impasse in Mitochondrial Diseases: a Transcriptomic Approach in Fibroblasts and Blood Cells NCT06621732NA2 sites๐Ÿ“ Nice๐Ÿ“ Montpellier Centre Hospitalier Universitaire de Nice ยท Tests: cutanous biopsy and blood sample
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