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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Muscle Invasive Bladder Cancer

Phase II Study of Oral Metformin for Intravesical Treatment of Non-muscle-invasive Bladder Cancer NCT03379909Phase 23 sites📍 Nijmegen📍 Rotterdam📍 Amsterdam Academisch Medisch Centrum - Universiteit van Amsterdam (AM… · Tests: Metformin Immediate Chemotherapy Following Resection for High-Risk Non-Muscle-Invasive Bladder Cancer NCT06889623NA1 site📍 Shanghai Changhai Hospital · Tests: Immediate postoperative chemotherapy A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003) NCT07222488Phase 1, Phase 217 sites📍 Bakersfield📍 New Brunswick📍 Myrtle Beach Merck Sharp & Dohme LLC · Tests: MK-3120 A Study Comparing the Necessity of a Second Transurethral Resection in High-Risk Non-Muscle-Invasive Bladder Cancer Patients With Negative Results From Post-Initial Resection Urine Genome-Wide Low-Depth Sequencing NCT07036731NA1 site📍 Nanjing The First Affiliated Hospital with Nanjing Medical Universi… · Tests: Urine biomarker -Guided without reTURBT Increasing Pre-Surgical Identification of Muscle Invasive Tumor Evaluations Prior to Planned Cystectomy (INSITE) NCT06396533n/a2 sites📍 Omaha📍 Philadelphia Fox Chase Cancer Center Multicenter Clinical Trial on the Effectiveness and Safety of Instillation of BCG and Alternative BCG Protocols for Intermediate and High-risk Non-muscle Invasive Bladder Cancer NCT06441110Phase 31 site📍 Fuzhou Fujian Medical University Union Hospital · Tests: Tislelizumab in Combination with Bacillus Calmette-Guérin Exploration of Novel AI-enabled Blue Light Enhanced Cystoscopy NCT07144319n/a12 sites📍 Tampa📍 Iowa City📍 Ann Arbor Photocure Tumor-informed ctDNA in Muscle-invasive Bladder Cancer for Evaluation of Residual/Recurrent Disease - the TiMBER Trial NCT07726602n/a1 site📍 Portland OHSU Knight Cancer Institute · Tests: Non-Interventional Study A Study of SHR-1501 Alone or in Combination With BCG or SHR-1316 in Subjects With NMIBC NCT05410730Phase 1, Phase 21 site📍 Beijing Shanghai Hengrui Pharmaceutical Co., Ltd. · Tests: SHR-1501 Guiding Value of Urinary Tumor DNA Testing in Repeat Transurethral Resection of Non-Muscle-Invasive Bladder Cancer NCT07187635NA7 sites📍 Nanchang📍 Guangzhou📍 Xingtai Tianjin Medical University Second Hospital · Tests: Second Transurethral Resection of Bladder Tumor (re-TURBT), utDNA Testing (Urine Tumor DNA Detection) Safety, Tolerability, and Preliminary Efficacy of BH011 in Subjects With Non-Muscle-Invasive Bladder Cancer NCT06732531Phase 1, Phase 26 sites📍 Beijing📍 Xiamen📍 Changsha Zhuhai Beihai Biotech Co., Ltd · Tests: BH011 Sample Collection for Ongoing Research and Product Evaluation Study NCT07318051n/a1 site📍 Austin Natera, Inc. A Study to Investigate the Efficacy and Safety of Alpha1H as a Neoadjuvant Therapy in Participants With Low- to Intermediate-Risk/Low-Grade Papillary Non-Muscle Invasive Bladder Cancer NCT07804056Phase 31 site📍 Prague Hamlet Pharma AB · Tests: Alpha1H, Transurethral Resection of Bladder Tumor (TURBT), Intravesical Chemotherapy Testing the Addition of an Anti-Cancer Drug, Gemcitabine, to Usual Treatment (BCG Alone) in People Whose Non-Muscle Invasive Bladder Cancer (NMIBC) Came Back After Prior BCG Therapy NCT07000084Phase 360 sites📍 Birmingham📍 Fairbanks📍 Gilbert Alliance for Clinical Trials in Oncology · Tests: BCG Solution, Biopsy of Bladder, Cystoscopy, Computed Tomography, Magnetic Resonance Imaging EV + Toripalimab vs GC as Neoadjuvant Therapy in Locally Advanced/High-Risk MIBC NCT07647289Phase 21 site📍 Beijing Peking University Third Hospital · Tests: enfortumab vedotin (EV), Toripalimab, Gemcitabine (Chemotherapy), Cisplatin Investigator Grant (IG) 2022 27746 NCT06341478NA1 site📍 Milan IRCCS San Raffaele · Tests: various neoadjuvant therapies Toripalimab Combined With BCG Perfusion for the Treatment of HR-NMIBC After TURBT Surgery Exploration NCT07307456Phase 21 site📍 Shanghai Changhai Hospital · Tests: Treatment with toripalimab combined with BCG perfusion following transurethral resection of bladder tumor (TURBT) LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve NCT04752722Phase 1, Phase 2102 sites📍 Birmingham📍 Scottsdale📍 Tucson enGene, Inc. · Tests: EG-70 (phase 1), EG-70 (phase 2) Master Protocol, Surfactant Bladder Pre-Rinse and EG-70 (Substudy) Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study NCT05987241Phase 2, Phase 3505 sites📍 Phoenix📍 Phoenix📍 Tucson National Cancer Institute (NCI) · Tests: Biospecimen Collection, cfDNA or ctDNA Measurement, Computed Tomography, Cystoscopy, Magnetic Resonance Imaging Specimen Collection for Validation of UroAmp: A Next Generation Sequencing Platform for Detection and Surveillance of Bladder Cancer NCT07673016n/a23 sites📍 Oceanside📍 San Diego📍 San Jose Convergent Genomics, Inc. Studying the Relationship of Patient Positioning and Intravesical Bacillus Calmette Guerin Dwell Time to Improve the Treatment of Non-muscle Invasive Bladder Cancer NCT07474519Phase 41 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: Accelerometry, BCG Solution, BCG Solution, BCG Solution, Electronic Health Record Review Dutasteride in Patients With Low Grade Non-muscle Invasive Bladder Cancer NCT07420517Phase 21 site📍 Québec Paul Toren · Tests: Dutasteride (0.5mg) Clinical Trial to Evaluate Post-Operative Outcomes of Ureteral Stent vs Ureteral Stent Free Radical Cystectomy NCT07234968NA2 sites📍 Philadelphia📍 Philadelphia Thomas Jefferson University · Tests: Ureteral Stent Placement, No Ureteral Stent, Indocyanine Green with Fluorescence Imaging A Study of RAG-01 in Patients With Non-muscle-invasive Bladder Cancer (NMIBC) Who Have Failed Bacillus Calmette Guérin (BCG) Therapy NCT06351904Phase 13 sites📍 St Leonards📍 Melbourne📍 Melbourne Ractigen Therapeutics. · Tests: RAG-01 The Clinical Effectiveness and Safety of Intravesical Mitomycin-C and Gemcitabine Sequential Therapy NCT06388720Phase 21 site📍 Goyang-si National Cancer Center, Korea · Tests: Mitomycin-C, gemcitabine Home-Based Physical Activity Program With Digital App Versus Health Education Group for Improving Physical Activity Among Patients With Non-muscle Invasive Bladder Cancer, The EMPOWER Trial NCT07302230NA1 site📍 Seattle University of Washington · Tests: Internet-Based Intervention, Best Practice, Internet-Based Intervention, Exercise Intervention, Health Telemonitoring Neoadjuvant Zanidatamab + Tislelizumab + Chemotherapy for Selective Bladder Preservation in HER2-Positive MIBC NCT07296705Phase 212 sites📍 Fuzhou📍 Fuzhou📍 Putian Fujian Medical University Union Hospital · Tests: Zanidatamab, Tislelizumab, Cisplatin, Gemcitabine, Nab-paclitaxel A Study to Evaluate Efficacy and Safety of Hydeal Cyst® Intravesical Instillations in Patients Treated With Intravesical Chemotherapy or Immunotherapy in Non-muscle Invasive Bladder Cancer NCT06245603NA9 sites📍 Bergamo📍 Bologna📍 Foggia Istituto Oncologico Veneto IRCCS · Tests: Hydeal Cyst® Adaptive RADiation Therapy With Concurrent Sacituzumab Govitecan (SG) for Muscle Invasive Bladder Cancer NCT05833867Phase 11 site📍 Cleveland Shilpa Gupta, MD · Tests: Sacituzumab govitecan, Adaptive Radiotherapy Effect of Neoadjuvant Chemotherapy on MRI Accuracy Before Cystectomy NCT07202819NA2 sites📍 Asyut📍 Asyut Assiut University · Tests: Neoadjuvant Chemotherapy, Radical Cystectomy
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