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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Neoadjuvant Immunotherapy

Efficacy and Safety of Anlotinib Combined With Bemocizumab for Neoadjuvant Therapy of Esophageal Squamous Cell Carcinoma(ESCC) NCT07627347NA1 site๐Ÿ“ Guangzhou Nanfang Hospital, Southern Medical University ยท Tests: anlotinib+bevacizumab Neoadjuvant Radiotherapy Plus Tegafur, Oxaliplatin and Iparomlimab and Tuvonralimab in Resectable Gastric and GE-junction Cancer : A Randomized, Two-arm, Prospective Trial (TRIUNITE-05) NCT07165847Phase 21 site๐Ÿ“ Chongqing Daping Hospital and the Research Institute of Surgery of thโ€ฆ ยท Tests: Iparomlimab and Tuvonralimab, Oxaliplatin, Tegafur, Radiotherapy Iparomlimab and Tuvonralimab as Neoadjuvant Therapy for Resectable Hepatocellular Carcinoma With High Risk of Recurrence NCT06954116Phase 21 site๐Ÿ“ Wuhan Tongji Hospital ยท Tests: Iparomlimab and Tuvonralimab (QL1706), Partial hepatectomy Hypofractionated Radiotherapy Plus Immunotherapy Versus Conventional Radiotherapy in Locally Recurrent Rectal Cancer NCT06928584Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: Conventional Radiotherapy, Capecitabine, 5-fluorouracil, folinic acid, Oxaliplatin A Phase II Study of Toripalimab Combined With Sequential Neoadjuvant Chemoradiotherapy in Patients With Esophageal Squamous Cell Carcinoma NCT06843889Phase 21 site๐Ÿ“ Guangzhou Nanfang Hospital, Southern Medical University ยท Tests: Toripalimab (240mg day1, Q3W*3cycle) Feasibility of a Lifestyle Intervention for Women With Triple-negative Breast Cancer Under Neoadjuvant Immunotherapy NCT07311083NA1 site๐Ÿ“ Essen Kliniken Essen-Mitte ยท Tests: switching to a high-fibre diet, official dietary recommendations Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3 NCT07595874Phase 211 sites๐Ÿ“ Goodyear๐Ÿ“ Corona๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Balstilimab, Biospecimen Collection, Botensilimab, Computed Tomography, Magnetic Resonance Imaging I-SPY TRIAL: Neoadjuvant and Personalized Adaptive Novel Agents to Treat Breast Cancer NCT01042379Phase 242 sites๐Ÿ“ Birmingham๐Ÿ“ Scottsdale๐Ÿ“ Tucson QuantumLeap Healthcare Collaborative ยท Tests: Standard Therapy, AMG 386 with or without Trastuzumab, AMG 479 (Ganitumab) plus Metformin, MK-2206 with or without Trasโ€ฆ Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer. NCT06940388Phase 22 sites๐Ÿ“ Mainz๐Ÿ“ Petah Tikva brenner baruch ยท Tests: Tislelizumab, Total neoadjuvant therapy (TNT) Capecitabine Plus Pembrolizumab in Patients With Triple Negative Breast Cancer After Chemo-immunotherapy and Surgery NCT05973864Phase 220 sites๐Ÿ“ Amiens๐Ÿ“ Avignon๐Ÿ“ Bayonne UNICANCER ยท Tests: Pembrolizumab injection, Capecitabine tablets, Local radiotherapy Comparing Neoadjuvant/Adjuvant GVAX vs a mKRASvax Given With Anti-PD-1 and Anti-CD137 for Surgically Resectable Pancreatic Cancer NCT06782932Phase 1, Phase 21 site๐Ÿ“ Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins ยท Tests: AGEN2373, Balstilimab, Cyclophosphamide, GVAX, AGEN2373 (RP2D) Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer NCT07528209Phase 31 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Pucotenlimab combine with CAPOX, CAPOX PHOENIX DDR/Anti-PD-L1 Trial: A Pre-surgical Window of Opportunity and Post-surgical Adjuvant Biomarker Study of DNA Damage Response Inhibition With or Without Anti-PD-L1 Immunotherapy in Patients With Neoadjuvant Treatment Resistant Residual Triple Negative Breast Cancer NCT03740893Phase 26 sites๐Ÿ“ Bournemouth๐Ÿ“ London๐Ÿ“ Manchester Institute of Cancer Research, United Kingdom ยท Tests: AZD6738, Olaparib, Durvalumab Induction Chemo-Immunotherapy + Radiotherapy vs Concurrent Chemoradiotherapy for Unresectable Locally Advanced Esophageal Squamous Cell Carcinoma NCT07559045Phase 21 site๐Ÿ“ Zunyi Second Affiliated Hospital of Zunyi Medical University ยท Tests: Paclitaxel plus Cisplatin or Carboplatin (Induction Chemotherapy), Weekly Paclitaxel plus Cisplatin or Carboplatin (Conโ€ฆ Low-dose Radiation Combined With Neoadjuvant Immunochemotherapy for Esophageal Squamous Cell Carcinoma NCT06446726Phase 21 site๐Ÿ“ Chengdu Sichuan University ยท Tests: Tislelizumab, Low-dose radiotherapy, Nab-paclitaxel, Cisplatin Towards Cure Via Only Ultra-short ICB in CSCC NCT06823479Phase 25 sites๐Ÿ“ Maastricht๐Ÿ“ Amsterdam๐Ÿ“ Amsterdam The Netherlands Cancer Institute ยท Tests: Nivolumab, Ipilumimab Iparomlimab/Tuvonralimab Combined With Nab-paclitaxel and Cisplatin as Neoadjuvant Therapy for Locally Advanced Cervical Cancer NCT07876154Phase 21 site๐Ÿ“ Xi'an Xijing Hospital ยท Tests: Iparomlimab/Tuvonralimab, nab-paclitaxel, Cisplatin, Carboplatin (AUC 5) Microbiome Immunotherapy Neoadjuvant Assessment NCT06709651n/a1 site๐Ÿ“ Cork University College Cork Neoadjuvant Lenvatinib and Pembrolizumab for IVC Tumor Thrombus NCT05319015Phase 21 site๐Ÿ“ Dallas University of Texas Southwestern Medical Center ยท Tests: Neoadjuvant Lenvatinib, Neoadjuvant Pembrolizumab, Radical nephrectomy, IVC thrombectomy, retroperitoneal lymph node diโ€ฆ Induction Chemotherapy Combined With Neoadjuvant Immunotherapy for MSS Colon Cancer NCT05914389Phase 21 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Oxaliplatin, Capecitabine, Anti-PD-L1 Monoclonal Antibody, Clostridium butyricum, Colectomy 68Ga-grazytracer PET/CT for Early Assessment of Response to Neoadjuvant Immunotherapy in Resectable NSCLC NCT06756217n/a1 site๐Ÿ“ Shanghai Ruijin Hospital ยท Tests: 68Ga-grazytracer PET/CT Neoadjuvant ChemoRadiotherapy Followed by Immunotherapy and Surgery for Resectable Esophageal Squamous Cell Carcinoma๏ผˆCRIS-2 Trial๏ผ‰ NCT06509568Phase 21 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: Neoadjuvant chemoradiotherapy followed by immunotherapy, Neoadjuvant chemoimmunotherapy Effect of Infusion Timing on Pathologic Response to Neoadjuvant Immunotherapy in Resectable Non-Small Cell Lung Cancer NCT07251582Phase 32 sites๐Ÿ“ Changsha๐Ÿ“ Changsha Hunan Province Tumor Hospital ยท Tests: Time of Day-based Assignment for Infusion of Immune Checkpoint Inhibitor (e.g., toripalimab, or pembrolizumab) + platinโ€ฆ Nimotuzumab Combined With Immunotherapy and Chemotherapy in the Treatment of Locally Advanced Head and Neck Squamous Cell Carcinoma NCT07601737Phase 21 site๐Ÿ“ Shanghai Shanghai General Hospital, Shanghai Jiao Tong University Scโ€ฆ ยท Tests: Nimotuzumab Injection, Tislelizumab, Albumin-Bound Paclitaxel /nab-Paclitaxel, Cisplatin (Or Carboplatin), Radical surgโ€ฆ Circadian Rhythm Impact on TNBC Response to Neoadjuvant Immunotherapy NCT06880029Phase 1, Phase 21 site๐Ÿ“ Vila Nova de Gaia Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E. ยท Tests: Morning pembrolizumab infusions Induction High-Low Dose Radiotherapy Plus Anti-PD-1 Followed by Definitive Radiotherapy in Recurrent Nasopharyngeal Carcinoma (Single-Arm Phase II) NCT07277764Phase 21 site๐Ÿ“ Nanchang Jiangxi Provincial Cancer Hospital ยท Tests: High-Low Dose Radiotherapy Multimodal AI for Predicting Response to Neoadjuvant Immunotherapy in Gastric Cancer (PRISM-GC) NCT07401199n/a9 sites๐Ÿ“ Fuyang๐Ÿ“ Cangzhou๐Ÿ“ Hengshui Qun Zhao ยท Tests: Standard of Care PD-1 Inhibitors, Multimodal AI Assessment Evaluating and Monitoring Immune and Clinical Responses in Early-Stage Triple Negative Breast Cancer Undergoing Neoadjuvant Chemo-immunotherapy With Pembrolizumab NCT05877859n/a1 site๐Ÿ“ Atlanta Emory University Study of Neoadjuvant Cemiplimab and Dupilumab in Early-Stage Non-Small Cell Lung Cancer NCT06743581NA2 sites๐Ÿ“ Montreal๐Ÿ“ Montreal Centre hospitalier de l'Universitรฉ de Montrรฉal (CHUM) ยท Tests: Cemiplimab, Dupilumab Neoadjuvant Intra-tumor Double Immunotherapy for Lung Cancer. NCT06492421Phase 21 site๐Ÿ“ Guanzhou Second Affiliated Hospital of Guangzhou Medical University ยท Tests: ipilimumab, pembrolizumab, durvalumab, idarubicin, bevacizumab
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