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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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17 recruiting trials

for Newly-diagnosed Ph+ Acute Lymphoblastic Leukemia

Olverembatinib Plus Venetoclax and Dexamethasone for Treatment-naïve Ph+ Acute Lymphoblastic Leukemia NCT06082934Phase 1, Phase 21 site📍 Xi'an Xijing Hospital · Tests: Olverembatinib plus venetoclax and dexamethasone Efficacy and Safety of TKI Combined With Chemotherapy and Sequential CAR-T Cells in ND Adult Patients With Ph+ ALL NCT06481228NA1 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: CAR-T cells, Venetoclax, Olverembatinib ALL Backbone in AYAs NCT07227584Phase 21 site📍 Boston Dana-Farber Cancer Institute · Tests: Blinatumomab, Oncaspar, Cyclophosphamide, Cytarabine, Dexamethasone A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL) NCT06124157Phase 2161 sites📍 Birmingham📍 Phoenix📍 Tucson National Cancer Institute (NCI) · Tests: Biospecimen Collection, Blinatumomab, Bone Marrow Biopsy, Calaspargase Pegol, Cyclophosphamide Full-course Immunotherapy Combined With Chemotherapy in Newly Diagnosed B-cell Acute Lymphoblastic Leukemia NCT07564453Phase 21 site📍 Suzhou The First Affiliated Hospital of Soochow University · Tests: Blinatumomab, Induction Chemotherapy, Hyper-CVAD, Allogeneic hematopoietic stem cell transplantation, CAR-T cell therapy RDC-Blinatumomab Versus hyperCVAD for Ph-negative B-ALL. NCT06250959Phase 21 site📍 Suzhou Chen Suning · Tests: Blinatumomab Injection [Blincyto], Doxorubicin Efficacy and Safety of Low-dose Chemotherapy Plus Immuno-targeted Drugs in Newly Diagnosed Adult Ph- B-ALL NCT06387121Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Vincristine, Cyclophosphamide, Dexamethasone, Venetoclax, Inotuzumab ozogamicin Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma NCT06918431Phase 28 sites📍 Phoenix📍 Duarte📍 Irvine City of Hope Medical Center · Tests: Asparaginase Erwinia chrysanthemi, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomogra… A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1) NCT06051409Phase 390 sites📍 Birmingham📍 Duarte📍 Los Angeles Ascentage Pharma Group Inc. · Tests: Olverembatinib, Investigator's choice of TKI A Study of LP-118 In Combination With Ponatinib, Dexamethasone And Blinatumomab For Adults With Newly-Diagnosed, BCR::ABL1-Positive Acute Lymphoblastic Leukemia (ALL) NCT07614022Phase 12 sites📍 Charlotte📍 Winston-Salem Wake Forest University Health Sciences · Tests: LP-118 A Single-arm, Open-label Study of Olverembatinib, CD3/CD19 Bispecific T-cell Engager, and Chidamide in Patients With Newly Diagnosed Ph+ALL NCT06220487Phase 21 site📍 Guangzhou Nanfang Hospital, Southern Medical University · Tests: Prednisone, Olverembatinib, Blinatumomab, Chidamide Inotuzumab Ozogamicin and Blinatumomab With or Without Ponatinib in Treating Patients With Newly Diagnosed, Recurrent, or Refractory CD22-Positive B-Lineage Acute Lymphoblastic Leukemia NCT03739814Phase 2285 sites📍 Birmingham📍 Anchorage📍 Anchorage National Cancer Institute (NCI) · Tests: Biospecimen Collection, Blinatumomab, Bone Marrow Aspiration, Bone Marrow Biopsy, Inotuzumab Ozogamicin Dose-Adjusted EPOCH With or Without Rituximab Plus Ponatinib for the Treatment of Newly-Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia/Lymphoma NCT07224100Phase 21 site📍 Seattle University of Washington · Tests: Cyclophosphamide, Doxorubicin, Etoposide, Filgrastim, Pegfilgrastim Newly-diagnosed Pediatric Ph-positive B-ALL Protocol NCT07152041Phase 324 sites📍 Hefei📍 Chongqing📍 Fuzhou Institute of Hematology & Blood Diseases Hospital, China · Tests: olverembatinib Efficacy, Safety, and Pharmacokinetics of ThisCART19A Combined With Olverembatinib in Patients With Newly Diagnosed Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia. NCT07074496EARLY Phase 12 sites📍 Suzhou📍 Suzhou The First Affiliated Hospital of Soochow University · Tests: ThisCART19A, Fludarabine, Cyclophosphamide, Olverembatinib Chemotherapy With Targeted-Immunotherapy for Newly Diagnosed Ph+ ALL NCT07493161NA1 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Olverembatinib, Venetoclax, Blinatumomab, Chemotherapy Backbone Regimens, Allogeneic Hematopoietic Stem Cell Transplant… Efficacy and Safety of Chemotherapy Combined With CAR-T Cells in Newly Diagnosed Adult Patients With Ph- B-ALL NCT06481241NA1 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: CAR-T cells, Venetoclax
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