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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Pleural Effusions

Dual-targeting HER2 and PD-L1 CAR-T for Solid Tumors NCT04684459EARLY Phase 11 site📍 Chengdu Sichuan University · Tests: Dual-targeting HER2 and PD-L1 CAR-T cells UNC Pleural Fluid Registry NCT05620329n/a1 site📍 Chapel Hill UNC Lineberger Comprehensive Cancer Center A Phase II Study of AK112 (PD1/VEGF Bispecific) in Combination with Chemotherapy in Patients with NSCLC NCT06769295Phase 21 site📍 Chengdu Sichuan University · Tests: AK112 A Phase Ib/II Clinical Trial of M701 in the Treatment of Malignant Pleural Effusions Caused by NSCLC NCT05543330Phase 1, Phase 21 site📍 Hangzhou Wuhan YZY Biopharma Co., Ltd. · Tests: M701 pleural infusion, Pleural drainage, Cisplatin pleural infusion Dual-targeting VEGFR1 and PD-L1 CAR-T for Pleural, Peritoneal, or Leptomeningeal Metastases NCT05477927Phase 11 site📍 Chengdu Sichuan University · Tests: Dual-targeting VEGFR1/PD-L1 CAR-T cells Oncodrivers in Malignant Pleural Effusions Associated With Non-small Cell Lung Cancer: A Prospective Study. NCT04806412NA1 site📍 Næstved Naestved Hospital · Tests: meassurement of PD-L1, ALK, EGFR Confocal Laser Endomicroscopy Guided Medical Thoracoscopy for the Diagnosis of Pleural Disease NCT06741839NA1 site📍 Beijing China-Japan Friendship Hospital · Tests: Confocal laser endomicroscopy guided pleural biopsy using medical thoracoscopy, Plerual biopsy using medical thoracosco… Organoid-guided Personalized Treatment of Pleural Effusion NCT06959173n/a1 site📍 Zhengzhou Henan Cancer Hospital 16F vs 24F Chest Drain After Minimally Invasive Lobectomy and/or Segmentectomy NCT06958848NA1 site📍 Basel University Hospital, Basel, Switzerland · Tests: 16 F chest tube, 24 F chest tube, Early removal, Standard removal First Local Anaesthesia Thoracoscopy for Pleural Effusion Diagnosis. NCT06946498NA1 site📍 Athens National and Kapodistrian University of Athens · Tests: Local Anesthesia Thoracoscopy, Pleuroscopy with Rigid Thoracoscope and Forceps biopsies Indwelling Pleural Catheters With or Without Doxycycline in Treating Patients With Malignant Pleural Effusions NCT03465774n/a1 site📍 Houston M.D. Anderson Cancer Center · Tests: Doxycycline, Indwelling Catheter, Quality-of-Life Assessment, Questionnaire Administration, Survey Administration Fast TILs to Treat Metastatic Cancer Patients With Pleural Disease NCT07192900Phase 11 site📍 Pittsburgh David Bartlett, MD · Tests: locally manufactured adoptive cellular therapy (ACT) product, Interleukin-2 Tocilizumab Delivered Via Pleural and Peritoneal Catheters in Patients With Advanced Metastatic Cancer NCT06016179Phase 11 site📍 Pittsburgh Allegheny Singer Research Institute (also known as Alleghen… · Tests: Tocilizumab Fast TILs to Treat Metastatic Pleural Effusions From Epithelial or Mesothelial Primary Tumors NCT07443020Phase 11 site📍 Pittsburgh Allegheny Singer Research Institute (also known as Alleghen… · Tests: locally manufactured adoptive cellular therapy (ACT) product, Interleukin-2 (IL-2) Continuation Of a Study to Investigate the Effect of Thoracocentesis on Neural Respiratory Drive in Pleural Effusion NCT05945043n/a1 site📍 London Guy's and St Thomas' NHS Foundation Trust · Tests: Surface parasternal eletromyogram, Surface diaphragm electromyogram, Parasternal muscle ultrasound, Breathlessness asse… Pleural Effusion Biomarkers in Lung Adenocarcinoma Patients NCT07012759n/a1 site📍 New Taipei City Fu Jen Catholic University · Tests: biomarkers Impact of Patient Position on Chemical Pleurodesis by Chest Ultrasound NCT07147270NA1 site📍 Cairo Ain Shams University · Tests: side to side and front to back rotation 30 minutes each DRAIN: DRainage in Acute Decompensated Heart faIlure With Pleural effusioNs NCT07419360NA1 site📍 Albany Albany Medical College · Tests: Thoracentesis Chest Drain Regular Flushing in Complicated Parapneumonic Effusions and Empyemas NCT06427538NA5 sites📍 Sterling Heights📍 Omaha📍 New York Vanderbilt University Medical Center · Tests: Saline Flush First-in-Human Expanded Cohort Study of Intrapleural Administration of TolueneSulfonamide in Patients With Malignant Pleural Effusion NCT07332858Phase 1, Phase 21 site📍 Beijing Gang Hou · Tests: Intrapleural administration of TolueneSulfonamide, Intrapleural administration of normal saline injection Diagnostic Utility of Mycobacterium Tuberculosis Cell-free DNA NCT06439810n/a1 site📍 Shatin Chinese University of Hong Kong · Tests: Mycobacterium tuberculosis (MTB) cell-free DNA (cfDNA) Feasibility of Ambulatory Talc. Pleurodesis NCT06682936NA1 site📍 Stockton-on-Tees David Rollins · Tests: ambulatory chest drain and talc pleurodesis A Phase Ib Study of JMKX000197 Injection in the Treatment of Malignant Pleural Effusion NCT06740019Phase 11 site📍 Beijing Jemincare · Tests: JMKX000197, Tube thoracostomy drainage Intraoperative Paravertebral Block and Postoperative Complications NCT07211529NA1 site📍 Wuhan Tongji Hospital · Tests: Paravertebral Block (PVB) Effect of Bubble Positive Expiratory Pressure and Segmental Breathing Versus Incentive Spirometry in Pleural Effusion NCT07248774NA1 site📍 Lahore Riphah International University · Tests: Bubble PEP, Incentive Spirometery Metagenomic Study in Parapneumonic Effusion NCT05394220n/a1 site📍 Hong Kong Chinese University of Hong Kong · Tests: 16S rRNA gene amplicon sequencing Validation and Clinical Utility of the Lung Sliding Index (LSI) for Differentiating Pulmonary Diseases NCT06983366n/a1 site📍 Asyut Assiut University · Tests: Lung Ultrasound Outcomes of a Single Chest Drain vs Two Drains NCT07125248NA1 site📍 Peshawar Khyber Teaching Hospital · Tests: Bilateral chest tube placement, Single drain placement Driving Pressure During Surgeries With High Risk for Postoperative Pulmonary Complications NCT07186933NA1 site📍 Pátrai University General Hospital of Patras · Tests: PEEP titration for Minimum Driving Pressure, Lung Protective Ventilation Evaluation of the Efficacy of Diagnostic Support Algorithms in Chest X-rays- LuAna Trial NCT06686251NA1 site📍 Curitiba Hospital Israelita Albert Einstein · Tests: App LuAna
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