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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Primary Immune Deficiency Disorder

An Phase Ib/II Clinical Trial of TCC1727 Combination Therapy in Advanced Solid Tumors NCT07371663Phase 1, Phase 23 sites📍 Beijing📍 Zhengzhou📍 Hangzhou Beijing Tide Pharmaceutical Co., Ltd · Tests: TCC1727 tablet 90mg, TCC1727 tablet 120mg, TCC1727 tablet 160mg, benmelstobart Injection Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a1 site📍 Sioux Falls Sanford Health Virus Specific Cytotoxic T-Lymphocytes (CTLs) for Refractory Cytomegalovirus (CMV) NCT03266640Phase 29 sites📍 Los Angeles📍 San Francisco📍 Indianapolis New York Medical College · Tests: viral specific cytotoxic t-lymphocytes Safety and Efficacy Study of Transplantation of Autologous CD34+ Cells Transduced With the G2ARTE Lentiviral Vector Expressing the DCLRE1C cDNA in Artemis (DCLRE1C) Deficient Severe Combined Immunodeficiency Patients (ARTEGENE) NCT05071222Phase 1, Phase 21 site📍 Paris Assistance Publique - Hôpitaux de Paris · Tests: ARTEGENE drug product EBV-specific Cytotoxic T-lymphocytes (CTLs) for Refractory EBV Infection NCT03266653Phase 28 sites📍 Los Angeles📍 San Francisco📍 Baltimore New York Medical College · Tests: cytotoxic t-lymphocytes An Observational Study Evaluating Patients With Chronic Liver Diseases Associated With Hepatic Steatosis NCT05335603n/a1 site📍 Hvidovre University of Copenhagen A Study Investigating the Effectiveness and Safety of Garadacimab for Treating Patients With Hereditary Angioedema (HAE) NCT07001280n/a22 sites📍 Phoenix📍 Miami📍 Saint Charles CSL Behring · Tests: No intervention Study of Autophagy and the Effects of GALIG Gene Products in HIV-1 Infected Patients Who Are Under Antiretroviral Therapy Since Primary-infection, Chronic Phase, or Never Treated. NCT04160455n/a1 site📍 Orléans Centre Hospitalier Régional d'Orléans · Tests: expression of a panel TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children NCT04414046Phase 21 site📍 St. Petersburg Johns Hopkins All Children's Hospital · Tests: Haploidentical Hematopoietic Cell Transplantation Enhancing the Clinical Management of CMF Through a National Pediatric and Adult Network Based on Biological and Genetic Data NCT07877727n/a4 sites📍 Avellino📍 Genova📍 Naples Istituto Giannina Gaslini Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT NCT01962415Phase 21 site📍 Pittsburgh Paul Szabolcs · Tests: Hydroxyurea, Alemtuzumab, Fludarabine, Melphalan, Thiotepa Improving HIV Testing, Linkage, and Retention in Care for Men Through U=U Messaging NCT05602376NA2 sites📍 East London📍 Cape Town Desmond Tutu HIV Foundation · Tests: U=U testing messaging scripts, U=U adherence messaging scripts Exercise Intervention and Immunodeficiency NCT07698197NA2 sites📍 Milford📍 North Haven Yale University · Tests: App-based exercise intervention A Randomised Placebo Controlled Trial of ART Plus Dual Long-acting HIV-specific Broadly Neutralising Antibodies (bNAbs). NCT04319367Phase 212 sites📍 Aarhus📍 Brighton📍 Edinburgh Imperial College London · Tests: Investigational Medicinal Product A Study of Lanadelumab in Teenagers and Adults With Hereditary Angioedema (HAE) in the Kingdom of Saudi Arabia NCT07263685n/a1 site📍 Riyadh Takeda · Tests: No intervention Real-life Ecological Momentary Assessment of Lived Burden in Hereditary AngioEdema NCT07448181n/a1 site📍 Milan Istituti Clinici Scientifici Maugeri SpA · Tests: ecological momentary assessment Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant Soft Capsule for On-Demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency NCT07266805Phase 332 sites📍 San Diego📍 Walnut Creek📍 St Louis Pharvaris Netherlands B.V. · Tests: Deucrictibant, Placebo, Deucrictibant, Placebo, Deucrictibant Pilot Trial of Allogeneic Blood or Marrow Transplantation for Primary Immunodeficiencies NCT02579967Phase 22 sites📍 Bethesda📍 Minneapolis National Cancer Institute (NCI) · Tests: Immunosuppression Only Conditioning -Closed with amendment L, Reduced Intensity Conditioning, Myeloablative Conditionin… Natural History of Sphingosine Phosphate Lyase Insufficiency Syndrome (SPLIS) NCT06669949n/a1 site📍 San Francisco University of California, San Francisco · Tests: no intervention Angioedema Biomarker Research Study NCT06210698n/a1 site📍 Wheaton Foundation For Rare Disease Research · Tests: Venipuncture Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning NCT03311503Phase 1, Phase 24 sites📍 Los Angeles📍 Atlanta📍 Boston David Williams · Tests: autologous CD34+ cell transduced with G2SCID vector Biologics And Clinical Immunology Cohort at Sinai NCT04784364n/a1 site📍 New York Icahn School of Medicine at Mount Sinai Evaluation of Patients With Immune Function Abnormalities NCT00128973n/a1 site📍 Bethesda National Institute of Allergy and Infectious Diseases (NIAI… Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma NCT05077527Phase 17 sites📍 Duarte📍 Chicago📍 New York AIDS Malignancy Consortium · Tests: Axicabtagene Ciloleucel, Cyclophosphamide, Fludarabine Genetic Study of Immunodeficiency: Search for New Genetic Causes for Primary Immunodeficiencies NCT02735824n/a1 site📍 Zurich University Children's Hospital, Zurich · Tests: Skin Biopsy, Mouth Swab or Saliva Collection, Blood Sampling Improving Deceased-Donor Kidney Transplant Outcomes Via a Single Intragraft Injection of C1 Esterase Inhibitor (IMPROVE TRIAL) NCT06919003Phase 24 sites📍 Los Angeles📍 Chicago📍 Kansas City National Institute of Allergy and Infectious Diseases (NIAI… · Tests: Berinert, Placebo for Berinert Shwachman-Diamond Syndrome Global Patient Survey and Partnering Platform NCT06999954n/a1 site📍 Woburn Shwachman-Diamond Syndrome Alliance Inc Hematopoietic Stem Cell Transplantation (HSCT) for Common Variable Immunodeficiency (CVID) and Other Autoimmune Manifestations of Primary Immune Regulatory Disorders (PIRD) NCT07284641Phase 21 site📍 Pittsburgh Paul Szabolcs · Tests: Hematopoietic stem cell transplant (HSCT) Safety and Efficacy of Mutation-targeted Precision Genetic Therapy for Ataxia-Telangiectasia (A-T) NCT07215416Phase 1, Phase 21 site📍 Boston Timothy Yu · Tests: Antisense oligonucleotide targeting the ATM gene V-IMMUNE: A Novel Immunoglobulin Therapy for Immunodeficiency NCT06954441Phase 31 site📍 Recife On Pharma Importadora, Exportadora e Distribuidora de Medic… · Tests: Intravenous immunoglobulin (IVIG)
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