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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Primary Mediastinal Diffuse Large B-cell Lymphoma

Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma NCT06536049Phase 1, Phase 23 sites๐Ÿ“ Minneapolis๐Ÿ“ Columbus๐Ÿ“ Richmond Yazeed Sawalha ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Epcoritamab Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T NCT06784726Phase 21 site๐Ÿ“ Seattle University of Washington ยท Tests: Odronextamab, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Chimeric Antigen Receptor T-Cell Therโ€ฆ CC-99282 + Rituximab Early Post CART for Non-Hodgkin's Lymphoma NCT06209619Phase 11 site๐Ÿ“ Columbus Nathan Denlinger ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Golcadomide, Positron Emission Tomography Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma NCT05077527Phase 17 sites๐Ÿ“ Duarte๐Ÿ“ Chicago๐Ÿ“ New York AIDS Malignancy Consortium ยท Tests: Axicabtagene Ciloleucel, Cyclophosphamide, Fludarabine Pembro Plus CAR T-cell Therapy in R/R in PMBCL NCT05934448Phase 22 sites๐Ÿ“ Boston๐Ÿ“ New York Jennifer Crombie, MD ยท Tests: Pembrolizumab, Lymphodepletion Chemotherapy, Chimeric Antigen Receptor (CAR) Therapy Infusion, Leukapheresis Gene Therapy for CD19-Positive Hematologic Malignancies (SENTRY-CD19) NCT06533579Phase 1, Phase 211 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Denver Vironexis Biotherapeutics Inc. ยท Tests: Dose Level 1, VNX-101, Dose Level 2, VNX-101, Dose Level 3, VNX-101, Dose Level 4, VNX-101 Sample Collection for Ongoing Research and Product Evaluation Study - Non-Hodgkin Lymphoma (SCORE-NHL) NCT07750886n/a1 site๐Ÿ“ Austin Natera, Inc. A Phase Ib/II Exploratory Clinical Trial of Memory-Enhanced 7ร—19-THEMIS CAR-T Cell Therapy for Relapsed/Refractory Large B-Cell Lymphoma NCT07788118Phase 1, Phase 21 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: 7ร—19-THEMIS CAR-T cells Immunotherapy in Lymphoma NCT06796517n/a2 sites๐Ÿ“ Seoul๐Ÿ“ Seoul Sung-Soo Park ยท Tests: CAR-T Therapy, Bispecific antibody, Antibody-Drug Conjugate, Monoclonal antibody, Proteasome Inhibitor Sintilimab Plus Rituximab Followed by R-CHOP Regimen in Untreated PMBL NCT06742502Phase 22 sites๐Ÿ“ Fuzhou๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Sintlimab+Rituximab follwed by R-CHOP(Cyclophosphamide, doxorubicin, vincristine, prednisone) A Study of Atlacabtagene Autoleucel CAR T-cells for Adults With Relapsed Large B-cell Lymphoma NCT06486051Phase 23 sites๐Ÿ“ Auckland๐Ÿ“ Christchurch๐Ÿ“ Newtown Malaghan Institute of Medical Research ยท Tests: Fludarabine, Cyclophosphamide, WZTL-002 CAR T-cells Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin Lymphoma NCT07097363Phase 21 site๐Ÿ“ Seattle University of Washington ยท Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Cyclophosphamide Epcoritamab, Rituximab, Gemcitabine and Oxaliplatin (R-GemOx) as Salvage Therapy Before Autologous Stem Cell Transplant for the Treatment of Relapsed/Refractory Diffuse Large B-Cell Lymphoma NCT07365306Phase 23 sites๐Ÿ“ Duarte๐Ÿ“ Newnan๐Ÿ“ Zion City of Hope Medical Center ยท Tests: Autologous Hematopoietic Stem Cell Transplantation, Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration, Bโ€ฆ A Study to Evaluate the Safety and Clinical Activity of GF- CART01 (CD20/19 CAR T Cell) in Subjects With Relapsed or Refractory B-Cell Hematological Malignancies NCT06703892Phase 11 site๐Ÿ“ Taipei GenomeFrontier Therapeutics TW Co., Ltd. ยท Tests: GF-CART01, GF-CART01, GF-CART01 Italian Observational Study on CAR-T Therapy for Lymphoma NCT06339255n/a1 site๐Ÿ“ Milan Paolo Corradini Study of Safety and Efficacy of TC011 in the Relapsed/Refractory Large B Cell Non-Hodgkin Lymphoma Patients NCT07473167Phase 1, Phase 21 site๐Ÿ“ Seoul TICAROS Co., Ltd. ยท Tests: TC011 Vaccine Responses in Patient With Multiple Myeloma and Non-Hodgkin Lymphoma After CAR-T Treatment NCT06784167n/a1 site๐Ÿ“ Portland OHSU Knight Cancer Institute ยท Tests: Non-Interventional Study Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma NCT05633615Phase 295 sites๐Ÿ“ Tucson๐Ÿ“ Tucson๐Ÿ“ Fayetteville SWOG Cancer Research Network ยท Tests: Axicabtagene Ciloleucel, Biospecimen Collection, Computed Tomography, Cyclophosphamide, Fludarabine Bio-CAR-T BS Study NCT05366569n/a1 site๐Ÿ“ Brescia Azienda Socio Sanitaria Territoriale degli Spedali Civili dโ€ฆ Loncastuximab Tesirine and Mosunetuzumab for the Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma NCT05672251Phase 21 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Loncastuximab Tesirine, Mosunetuzumab Study of SGR-1505 in Mature B-Cell Neoplasms NCT05544019Phase 136 sites๐Ÿ“ Gilbert๐Ÿ“ Newark๐Ÿ“ Pompano Beach Schrรถdinger, Inc. ยท Tests: SGR-1505 Rituximab (Rtx) + Tafasitamab in Combination With Allogeneic NK Cells for Treatment of Relapsed/Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL) NCT07225439Phase 12 sites๐Ÿ“ Cleveland๐Ÿ“ Cleveland Paolo Caimi, MD ยท Tests: Allogeneic NK cells, Rituximab, Tafasitamab, Interleukin-2, Fludarabine/cyclophosphamide CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma NCT06026319Phase 11 site๐Ÿ“ Boston Marcela V. Maus, M.D.,Ph.D. ยท Tests: CD79b-19 CAR T cells, Cyclophosphamide, Fludarabine Obinutuzumab and ICE Chemotherapy in Refractory/Recurrent CD20+ Mature NHL NCT02393157Phase 21 site๐Ÿ“ Valhalla New York Medical College ยท Tests: Obinutuzumab, Liposomal ARA-C, Ifosfamide, Carboplatin, Etoposide CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies NCT06208735Phase 17 sites๐Ÿ“ Calgary๐Ÿ“ Calgary๐Ÿ“ Vancouver British Columbia Cancer Agency ยท Tests: CLIC-2201 Long-term Follow-up Study of Lentiviral-based Gene-edited Immune Cell Therapy NCT05377307n/a5 sites๐Ÿ“ Kaohsiung๐Ÿ“ Taipei๐Ÿ“ Taipei Pell Bio-Med Technology Co., Ltd. ยท Tests: Pell's lentiviral-based gene-edited immune cell therapy Consolidation of First-Line MRD+ Remission With Cema-cel in Patients With LBCL NCT06500273Phase 286 sites๐Ÿ“ Gilbert๐Ÿ“ Hot Springs๐Ÿ“ Berkeley Allogene Therapeutics ยท Tests: cemacabtagene ansegedleucel, Fludarabine, Cyclophosphamide, Foresight CLARITYโ„ข IUO MRD test, powered by PhasED-Seqโ„ข Lentiviral Gene Therapy (Zamtocabtagene Autoleucel) LTFU NCT06116110n/a11 sites๐Ÿ“ Gilbert๐Ÿ“ Stanford๐Ÿ“ New Haven Miltenyi Biomedicine GmbH ยท Tests: Long-term Follow-Up Study of Efficacy and Safety of CRC01 in Adult Large B-cell Lymphoma and B-cell Acute Lymphoblastic Leukemia Patients NCT04836507Phase 1, Phase 22 sites๐Ÿ“ Seoul๐Ÿ“ Seoul Curocell Inc. ยท Tests: CRC01, Fludarabine, Cyclophosphamide Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy NCT06238648Phase 26 sites๐Ÿ“ Rochester๐Ÿ“ St Louis๐Ÿ“ Hackensack Academic and Community Cancer Research United ยท Tests: Biopsy, Biospecimen Collection, Computed Tomography, Epcoritamab, Magnetic Resonance Imaging
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