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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Prostatic Neoplasms, Castration-Resistant

Pilot of 18F-DCFPyL-PSMA PET in mCRPC Patients Receiving 117Lu-Vipivotide Tetraxetan NCT06099093Phase 42 sites📍 Boston📍 Boston Brigham and Women's Hospital · Tests: 18F-DCFPyl The COSMYC Trial (COmbined Suppression of MYC) NCT06922318Phase 21 site📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: ZEN-3694, Testosterone cypionate, Enzalutamide, Luteinizing hormone-releasing hormone (LHRH) analogue A Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of INV-9956 in Adult Patients With Advanced Metastatic Castration Resistant Prostate Cancer NCT06609005Phase 1, Phase 222 sites📍 Scottsdale📍 Newport Beach📍 Orange Shenzhen Ionova Life Sciences Co., Ltd. · Tests: INV-9956 Study of GVV858 as a Single Agent or in Combination With Endocrine Therapy in Patients With HR+/HER2- Breast Cancer and Other Advanced Solid Tumors NCT07288359Phase 1, Phase 216 sites📍 Atlanta📍 Nashville📍 San Antonio Novartis Pharmaceuticals · Tests: GVV858, Fulvestrant, Letrozole 177Lu-PSMA-617 With Liver Directed Therapy in Metastatic Castration Resistant Prostate Cancer NCT07145177Phase 11 site📍 San Francisco University of California, San Francisco · Tests: 177Lu-PSMA-617, Ablation, Trans-arterial chemoembolization (TACE), Positron Emission Tomography (PET)/Computerized tomo… A Study of Opevesostat (MK-5684) Versus Alternative Next-generation Hormonal Agent (NHA) in Metastatic Castration-resistant Prostate Cancer (mCRPC) Post One NHA (MK-5684-004) NCT06136650Phase 3330 sites📍 Tucson📍 Irvine📍 Los Angeles Merck Sharp & Dohme LLC · Tests: Opevesostat, Dexamethasone, Fludrocortisone acetate, Hydrocortisone, Abiraterone acetate ZEN003694 and Enzalutamide Versus Enzalutamide Monotherapy in Metastatic Castration-Resistant Prostate Cancer NCT04986423Phase 231 sites📍 Los Angeles📍 San Francisco📍 Whittier Zenith Epigenetics · Tests: ZEN003694, Enzalutamide Kidney Function and Risk Factors in Patients with Metastatic Castration-Resistant Prostate Cancer (mCRPC) Undergoing 177Lutetium-PSMA Radioligand Therapy: a Prospective Observational Study - KiRi-Trial NCT06720532n/a1 site📍 Munich Hannah Schaefer · Tests: characterization of renal function., Handgrip strength test, Questionaires Phase 2 Study of Ivonescimab in Patients With Cutaneous Squamous Cell Carcinoma NCT06567314Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Ivonescimab Imaging of Solid Tumors Using 18F-TRX NCT06942104Phase 11 site📍 San Francisco Rahul Aggarwal · Tests: 18F-TRX, Positron Emission Tomography (PET)/Computerized tomography (CT), Tumor Biopsy, Blood Specimen Collection A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1) NCT07723248Phase 312 sites📍 Coral Springs📍 Jeffersonville📍 Holland ORIC Pharmaceuticals · Tests: Rinzimetostat, Darolutamide, Enzalutamide, Docetaxel An Observational Study to Learn More About the Safety of Darolutamide in Men With Prostate Cancer in Korea NCT06334120n/a1 site📍 Multiple Locations Bayer · Tests: Darolutamide (Nubeqa, BAY1841788) Docetaxel and SX-682 in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma, Salivary Gland Carcinoma, and Advanced Prostate Cancer NCT07667400Phase 1, Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: SX-682, DTX Cell Therapy (STEAP1 CART) With Enzalutamide for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer NCT06236139Phase 1, Phase 21 site📍 Seattle Fred Hutchinson Cancer Center · Tests: Anti-STEAP1 CAR T-cells, Biopsy Procedure, Biospecimen Collection, Bone Scan, Computed Tomography Intrinsic Validity of Molecular Marker(s) Detection on Tissular Tumoral DNA to Predict the Efficacy of 177Lutetium-PSMA-617 (Lu-PSMA) Treatment for Castration-resistant Metastatic Prostate Cancer NCT06600802NA5 sites📍 Clermont-Ferrand📍 La Tronche📍 Pierre-Bénite Centre Jean Perrin · Tests: Blood samples Carboplatin or Olaparib for BRcA Deficient Prostate Cancer NCT04038502Phase 218 sites📍 West Los Angeles📍 Aurora📍 Washington D.C. VA Office of Research and Development · Tests: Carboplatin, Olaparib A Study of Tinengotinib (TT-00420) in Combination With Standard Treatments in People With Prostate Cancer NCT06457919Phase 1, Phase 212 sites📍 New Haven📍 Basking Ridge📍 Middletown Memorial Sloan Kettering Cancer Center · Tests: Tinengotinib, abiraterone acetate with prednisone, Enzalutamide A Study of Real-World Characteristics, Treatment Patterns, and Outcomes Among mCRPC Patients Previously Treated With an Androgen Receptor Pathway Inhibitor, Taxane-Based Chemotherapy, and Lutetium-177 Vipivotide Tetraxetan NCT07677267n/a1 site📍 East Hanover Novartis Pharmaceuticals Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors NCT07145255Phase 1, Phase 27 sites📍 San Francisco📍 Grand Rapids📍 East Brunswick MBrace Therapeutics · Tests: ADC Clinical Application of Near-infrared Whole Body Heat Shock Multimodal Technique in Treatment of Castration-resistant Prostate Cancer NCT06249750Phase 21 site📍 Hangzhou Pengyuan Liu · Tests: Immunotherapy, Targeted therapy, Hyperthermia ProBio: A Biomarker Driven Study in Patients With Metastatic Prostate Cancer NCT03903835Phase 332 sites📍 Aalst📍 Antwerp📍 Bruges Karolinska Institutet · Tests: Enzalutamide Oral Capsule, Abiraterone Oral Tablet, Carboplatin, Cabazitaxel 60 mg Solution for Injection, Docetaxel In… INSIDE: Identification of Genomic Screening Pathways in Cancer Patients With DNA Repair Alterations NCT06334809n/a2 sites📍 Candiolo📍 Orbassano Fondazione del Piemonte per l'Oncologia A Study to Investigate the Safety and Tolerability of Oral INR731 Single Agent or in Combination With Androgen Receptor Pathway Inhibitor (ARPI) in Patients With Metastatic Prostate Cancer NCT07570979Phase 113 sites📍 Boston📍 Dallas📍 Melbourne Novartis Pharmaceuticals · Tests: INR731, Enzalutamide, Abiraterone, Androgen deprivation therapy (ADT) A Study of NX-1607 in Adults With Advanced Malignancies NCT05107674Phase 117 sites📍 Duarte📍 Los Angeles📍 San Francisco Nurix Therapeutics, Inc. · Tests: NX-1607, Paclitaxel Difluoromethylornithine and High Dose Testosterone With Enzalutamide in Metastatic Castration-Resistant Prostate Cancer NCT06059118Phase 21 site📍 Baltimore Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins · Tests: DFMO, testosterone cypionate, Luteinizing hormone-releasing hormone (LHRH) analogue, Enzalutamide ACTinium in Castrate-RESistant Prostate Cancer After LUTEtium NCT07414940Phase 1, Phase 21 site📍 London University College, London · Tests: Actinium (225Ac) rhPSMA-10.1 A Study to Test Inavolisib Treatment in Participants With Metastatic Castration-Resistant Prostate Cancer NCT07287150Phase 248 sites📍 Los Angeles📍 San Francisco📍 Iowa City Hoffmann-La Roche · Tests: Inavolisib, Enzalutamide, Abiraterone, Docetaxel A Study of TRC003 in the Treatment of Patients With Progressive PSMA-positive mCRPC NCT07567521Phase 1, Phase 22 sites📍 Taiyuan📍 Shanghai C Ray Therapeutics · Tests: Radiopharmaceuticals The Bispecific PSMAxCD3 Antibody CC-1 in Patients with Castration Resistant Prostate Carcinoma NCT04104607Phase 12 sites📍 Tübingen📍 Heidelberg University Hospital Tuebingen · Tests: CC-1, PSMAxCD3 Phase Ib/IIa Dose Escalation and Expansion Study of [²¹²Pb]Pb-ADVC001 in Metastatic Prostate Cancer (TheraPb - Phase I/II Study). NCT05720130Phase 1, Phase 23 sites📍 Brisbane📍 Brisbane📍 Southport AdvanCell Pty Limited · Tests: [²¹²Pb]Pb-ADVC001 (Phase 1b), [²¹²Pb]Pb-ADVC001 (Phase 2a)
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