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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Rectal Cancer Stage III

Sacituzumab Govitecan in Metastatic Colorectal Cancer NCT06243393Phase 2, Phase 31 site๐Ÿ“ Heidelberg University Hospital Heidelberg ยท Tests: Sacituzumab Govitecan (SG), Physicians Choice (PhC). Neoadjuvant Therapy With Tislelizumab for dMMR/MSI-H Stage II-III Colorectal Cancer NCT07352280n/a1 site๐Ÿ“ Beijing Cancer Institute and Hospital, Chinese Academy of Medical Sโ€ฆ Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3 NCT07595874Phase 211 sites๐Ÿ“ Goodyear๐Ÿ“ Corona๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Balstilimab, Biospecimen Collection, Botensilimab, Computed Tomography, Magnetic Resonance Imaging Comparing Efficacy and Safety of Enlituoยฎ Versus Erbituxยฎ Plus FOLFOX in Locally Advanced/Metastatic Colorectal Cancer With RAS/BRAF Wild-type and MSS/pMMR Status. NCT07595276Phase 31 site๐Ÿ“ Guangzhou Taizhou Mabtech Pharmaceutical Co.,Ltd ยท Tests: Enlituoยฎ, Erbituxยฎ DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer NCT06275958Phase 336 sites๐Ÿ“ 's-Hertogenbosch๐Ÿ“ Alkmaar๐Ÿ“ Amstelveen Leiden University Medical Center ยท Tests: Doublet Chemotherapy, Standard Dose (100%), Doublet Chemotherapy, Dose-reduced (75%), Monotherapy, Standard Dose (100%)โ€ฆ UGT1A1-Based Irinotecan Therapy for Locally Advanced Rectal Cancer NCT05148767Phase 41 site๐Ÿ“ Hangzhou Zhejiang Cancer Hospital ยท Tests: Neoadjuvant chemoradiotherapy based on irinotecan Neoadjuvant CAPOX With or Without Pucotenlimab Plus Selective Radiotherapy for Locally Advanced Rectal Cancer NCT07528209Phase 31 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Pucotenlimab combine with CAPOX, CAPOX A Study of 2nd-line FOLFIRI ยฑ Bevacizumab vs. Irinotecan ยฑ Bevacizumab in mCRC NCT03303495Phase 31 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Bevacizumab, CPT-11, 5-FU Bolus, 5-FU Infusion, l-LV (dl-LV) A Randomized Controlled Trial of Plasma ctDNA Methylation-Guided Adjuvant Chemotherapy Decision-Making in High-Risk Stage III (T4N+ or T1-3N2) Colorectal Cancer NCT07562490Phase 21 site๐Ÿ“ Shanghai Fudan University ยท Tests: FOLFOX, Folfox plus Bevacizumab Short-Course Radiotherapy Followed by CAPOX With or Without Iparomlimab and Tuvonralimab in pMMR/MSS Locally Advanced Rectal Cancer NCT07686640Phase 31 site๐Ÿ“ Jinan Shandong Cancer Hospital and Institute ยท Tests: Short-Course Radiotherapy, Consolidation treatment (With ICIs), Consolidation treatment (Without ICIs) A Study of Meaning-Centered Therapy for Mexican Adults With Advanced Cancer NCT07225309NA2 sites๐Ÿ“ New York๐Ÿ“ Mexico City Memorial Sloan Kettering Cancer Center ยท Tests: Meaning-Centered Psychotherapy for Latinos /MCP-L Other Oncogene Mutations for Anti-EGFR Efficacy in Patients With Left-sided RAS-wild Type Metastatic Colorectal Cancer NCT06226857Phase 33 sites๐Ÿ“ Moscow๐Ÿ“ Moscow๐Ÿ“ Reutov City Clinical Oncology Hospital No 1 ยท Tests: Cetuximab The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors NCT04624555n/a1 site๐Ÿ“ Cleveland Case Comprehensive Cancer Center Surgery Plus Chemo Versus Chemoradiotherapy Followed by Surgery Plus Chemo for Locally Recurrent Rectal Cancer NCT04288999Phase 345 sites๐Ÿ“ Chiba๐Ÿ“ Gifu๐Ÿ“ Hidaka National Cancer Center Hospital East ยท Tests: Chemotherapy, Preoperative radiotherapy, Procedure ctDNA Monitoring to Predict the Efficacy of TNT for Rectal Cancer NCT06589388n/a1 site๐Ÿ“ Ho Chi Minh City Gene Solutions Zanzalintinib Alone or in Combination With Pembrolizumab and Berahyaluronidase Alfa in Participants With Colorectal Cancer With Molecular Residual Disease NCT07750158Phase 313 sites๐Ÿ“ Council Bluffs๐Ÿ“ Grand Island๐Ÿ“ Grand Island Exelixis ยท Tests: Zanzalintinib, Pembrolizumab (+) Berahyaluronidase alfa, Placebo Evaluation of Quality of Life and Utilities Following Surgical Treatment of Stage I-IV Rectal Cancer NCT02107105n/a1 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Quality-of-Life Assessment, Questionnaire Administration Adjuvant Chemotherapy Combined With Targeted Therapy or Not in the T3-4N2 Colorectal Cancer Patients NCT05797467Phase 31 site๐Ÿ“ Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University ยท Tests: FOLFOX chemotherapy regimens, Bevacizumab Early Detection of Advanced Adenomas and Colorectal Cancer NCT06342440n/a6 sites๐Ÿ“ Monrovia๐Ÿ“ San Diego๐Ÿ“ Dalian City of Hope Medical Center ยท Tests: DENEB Immune Checkpoint Inhibitor Response in Solid Tumors Using a Live Tumor Diagnostic Platform NCT06349642n/a3 sites๐Ÿ“ Phoenix๐Ÿ“ Jacksonville๐Ÿ“ Rochester Mayo Clinic ยท Tests: Biospecimen Collection, Tissue Collection Ganglion Impar Neurolysis for the Improvement of Radiation-Induced Pain During Localized Anal or Perianal Skin Cancer Treatment NCT07112690NA2 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Electronic Health Record Review, Fluoroscopy, Ganglion Impar Neurolysis, Questionnaire Administration Magnetic Resonance Tumour Regression Grade (mrTRG) as a Novel Biomarker - Phase III Non CTIMP Trial NCT02704520NA10 sites๐Ÿ“ Aberdeen๐Ÿ“ Basingstoke๐Ÿ“ Stoke-on-Trent Imperial College London ยท Tests: High resolution MRI scan, mrTRG assessment MRD-guided Deferred Adjuvant Therapy in Resectable Early-stage Colon Cancer NCT06204484NA1 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: CAPEOX adjuvant therapy, deferred CAPEOX adjuvant therapy, mFOLFOXIRI intensive adjuvant therapy Clinical Research on the Treatment Model of Ambulatory Surgery for Colorectal Cancer NCT06637215NA1 site๐Ÿ“ Shenyang First Hospital of China Medical University ยท Tests: laparoscopic colorectal day surgery, traditional laparoscopic colorectal surgery A Study of Tucidinostat in Combination With Sintilimab and Bevacizumab in MSS/pMMR Colorectal Cancer Patients NCT06497985Phase 31 site๐Ÿ“ Guangzhou Chipscreen Biosciences, Ltd. ยท Tests: Tucidinostat, Sintilimab, Bevacizumab, Fruquintinib Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration GUIDE.MRD-01-CRC: Clinical Validation and Benchmarking of Top Performing ctDNA Diagnostics - Colorectal Cancer NCT06111105n/a15 sites๐Ÿ“ Graz๐Ÿ“ Graz๐Ÿ“ Copenhagen Claus Lindbjerg Andersen mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC NCT06791512Phase 31 site๐Ÿ“ Guangzhou Jun Huang ยท Tests: mFOLFOX6 + Bevacizumab + PD-1 monoclonal antibody, mFOLFOX6 FAPI-Guided Radiotherapy With Cadonilimab and Standard Chemotherapy for Colorectal Peritoneal Metastasis: A Phase III Randomized Controlled Trial (TORHC-PM02) NCT07815834Phase 31 site๐Ÿ“ Shanghai Fudan University ยท Tests: Second-Line Chemotherapy, Radiation Therapy, Cadonilimab (AK104) Non Inferiority Study of Preoperative Chemotherapy Without Pelvic Irradiation for Rectal Cancer NCT03875781Phase 31 site๐Ÿ“ Le Kremlin-Bicรชtre Assistance Publique - Hรดpitaux de Paris ยท Tests: Chemotherapy, Radiochemotherapy
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