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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Recurrent Glioblastoma

Registry of Patients With Brain Tumors Treated With STaRT (GammaTiles) NCT04427384n/a54 sites๐Ÿ“ Phoenix๐Ÿ“ Little Rock๐Ÿ“ Castro Valley GT Medical Technologies, Inc. ยท Tests: GammaTile Evaluating Safety, Tolerability, and Preliminary Efficacy of YSCH-01 Monotherapy and in Combination With Atezolizumab for Recurrent Glioblastoma NCT07538128EARLY Phase 11 site๐Ÿ“ Shanghai Huashan Hospital ยท Tests: YSCH-01, Atezolizumab (1200 mg every three weeks) LITT for Ultra-early GBM Recurrence NCT07616986NA1 site๐Ÿ“ Bern Insel Gruppe AG, University Hospital Bern ยท Tests: LITT D2C7-IT + 2141-V11 Combination Post-resection in rGBM NCT06455605Phase 11 site๐Ÿ“ Durham Darell Bigner ยท Tests: D2C7-IT, 2141 V11 Local, Targeted Therapy With Alpha Emitter [225Ac]Ac-DOTA-SP (TAT) in Glioma (WHO G3-G4) Progression NCT06975332NA2 sites๐Ÿ“ Warsaw๐Ÿ“ Warsaw Medical University of Warsaw ยท Tests: Local, targeted therapy with alpha emitter [225Ac]Ac-DOTA-SP (TAT) Sonodynamic Therapy With SONALA-001 or 5-ALA HCL and Magnetic Resonance Guided Focused Ultrasound for the Treatment of Progressive or Recurrent Glioblastoma NCT07076472EARLY Phase 11 site๐Ÿ“ Rochester Mayo Clinic ยท Tests: Aminolevulinic Acid Intravenous Formulation SONALA-001, Biospecimen Collection, Computed Tomography, Electronic Health โ€ฆ A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastinยฎ Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients NCT06496971Phase 32 sites๐Ÿ“ Taipei๐Ÿ“ Taoyuan NaviFUS Corporation ยท Tests: Bevacizumab, Microbubble, Low-Intensity Focused Ultrasound A Feasibility Study to Evaluate the Safety of the TheraSphere Glioblastoma (GBM) Device in Patients With Recurrent GBM NCT05303467Phase 19 sites๐Ÿ“ Birmingham๐Ÿ“ San Diego๐Ÿ“ San Francisco Boston Scientific Corporation ยท Tests: TheraSphere GBM Phase 1 Trial of D2C7-IT in Combination With 2141-V11 for Recurrent Malignant Glioma NCT04547777Phase 11 site๐Ÿ“ Durham Darell Bigner ยท Tests: D2C7-IT, 2141-V11 Radiodynamic Therapy (RDT) With Gliolan in Patients With First Recurrence of Brain Tumor NCT05590689Phase 1, Phase 21 site๐Ÿ“ Mรผnster Universitรคt Mรผnster ยท Tests: Gliolan, Radiodynamic therapy [177Lu]Lu-DOTA-EB-RGD2 Therapy in Patients With Recurrent High-grade Glioma NCT07655869EARLY Phase 12 sites๐Ÿ“ Beijing๐Ÿ“ Beijing Beijing Tiantan Hospital ยท Tests: [177Lu]Lu-DOTA-EB-RGD2 Study in Children and Adolescents of 177Lu-DOTATATE (Lutatheraยฎ) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site๐Ÿ“ Boadilla del Monte Fundaciรณn de investigaciรณn HM ยท Tests: Olaparib; 177Lu-DOTATATE A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma NCT07464925Phase 13 sites๐Ÿ“ Tampa๐Ÿ“ Chicago๐Ÿ“ New York Tetragon Biosciences Ltd ยท Tests: GLIX1 Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma NCT06410248Phase 11 site๐Ÿ“ Chicago Northwestern University ยท Tests: Biospecimen Collection, Magnetic Resonance Imaging, Questionnaire Administration, Resection, Temozolomide A Clinical Trial of P134 Cells in Recurrent Glioblastoma NCT07318818Phase 1, Phase 21 site๐Ÿ“ Beijing Tasly Pharmaceutical Group Co., Ltd ยท Tests: P134 cell injection Collection of Blood and Urine Samples in Patients Receiving Radiation Therapy for Glioblastoma Multiforme NCT00083512n/a1 site๐Ÿ“ Bethesda National Cancer Institute (NCI) Anti-EGFRvIII synNotch Receptor Induced Anti-EphA2/IL-13Ralpha2 CAR (E-SYNC) T Cells NCT06186401Phase 11 site๐Ÿ“ San Francisco Hideho Okada, MD, PhD ยท Tests: E-SYNC T Cells, Cyclophosphamide (non-investigational), Fludarabine (non-investigational), Leukapheresis, Surgical reseโ€ฆ Alpha Radiation Emitters Device (DaRT) for the Treatment of Recurrent Glioblastoma NCT06910306NA3 sites๐Ÿ“ Scottsdale๐Ÿ“ New York๐Ÿ“ Columbus Alpha Tau Medical LTD. ยท Tests: Device :DaRT seeds BRiTE - Bispecific T Cell Engager for Patients With Glioblastoma NCT04903795Phase 11 site๐Ÿ“ Durham Mustafa Khasraw, MBChB, MD, FRCP, FRACP ยท Tests: hEGFRvIII-CD3 (BRiTE) Novel Indenoisoquinolone CMYC/TOPOISOMERASE 1 Inhibitor (LMP744) in Recurrent Glioblastoma NCT07416188Phase 1, Phase 21 site๐Ÿ“ Bethesda National Institute of Neurological Disorders and Stroke (NIโ€ฆ ยท Tests: LMP744, Conventional Surgery or Biopsy Study of Metabolic, Transcriptomic and Proteomic Characteristics in Relapsed Glioblastoma NCT06430424n/a1 site๐Ÿ“ Bordeaux University Hospital, Bordeaux ยท Tests: Relapsed glioblastoma Safety and Efficacy of CTX-009 With or Without CTX-471 for Recurrent Glioblastoma NCT07392957Phase 1, Phase 21 site๐Ÿ“ St Louis Washington University School of Medicine ยท Tests: CTX-009, CTX-471 Locoregional Administration of Genetically Engineered Cells (EGFR/IL13Rฮฑ2 Pool-CAR T Cells) for the Treatment of Recurrent or Progressive High-Grade Gliomas NCT07544992Phase 11 site๐Ÿ“ Duarte City of Hope Medical Center ยท Tests: Autologous Anti-EGFR/Anti-IL13Ralpha2 CAR T-cells, Biopsy Procedure, Biospecimen Collection, Echocardiography Test, FDGโ€ฆ Efficacy of the Combination of Trimipramine and Atezolizumab With Bevacizumab in Patients With Recurrent Glioblastoma: a Phase 2 Trial NCT07263438Phase 27 sites๐Ÿ“ Basel๐Ÿ“ Aarau๐Ÿ“ Bern Centre Hospitalier Universitaire Vaudois ยท Tests: Trimipramine, Cohort 1: Atezolizumab, Bevacizumab, Cohort 2: Atezolizumab, Cohort 2: Bevacizumab HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors NCT03911388Phase 13 sites๐Ÿ“ Birmingham๐Ÿ“ St Louis๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: G207 Investigator-Initiated Study of Imipramine Hydrochloride and Lomustine in Recurrent Glioblastoma NCT04863950Phase 21 site๐Ÿ“ San Antonio The University of Texas Health Science Center at San Antonio ยท Tests: Lomustine, Imipramine Hydrochloride A Multicenter Trial to Identify Optimal Atezolizumab Biomarkers in the Setting of Recurrent Glioblastoma. The MOAB Trial NCT06069726Phase 24 sites๐Ÿ“ San Francisco๐Ÿ“ Kansas City๐Ÿ“ Durham Duke University ยท Tests: Atezolizumab Sonocloud-9 in Association With Carboplatin Versus Standard-of-Care Chemotherapies (CCNU or TMZ) in Recurrent GBM NCT05902169Phase 356 sites๐Ÿ“ Phoenix๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles CarThera ยท Tests: SonoCloud-9 (SC9), Carboplatin, Lomustine, Temozolomide First-in Cancer-Type Phase I Study of FT536 for Recurrent WHO Grade 4 Astrocytoma NCT07560865Phase 11 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: FT536, Biopsy/ Intratumoral Injection/ Gross Tumor Resection, Blood/ Cerebrospinal Fluid/ Tumor Pathology A Digital Treatment Platform for the Delivery of Home-Based Sequential Therapy in Patients With Glioma, GHoST Trial NCT07074756NA2 sites๐Ÿ“ Jacksonville๐Ÿ“ Rochester Mayo Clinic ยท Tests: Chemotherapy, Computed Tomography, Internet-Based Intervention, Magnetic Resonance Imaging, Neurologic Examination
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