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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Refractory/Relapse Neuroblastoma

Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors NCT02508038Phase 11 site๐Ÿ“ Madison University of Wisconsin, Madison ยท Tests: TCRฮฑฮฒ+/CD19+ depleted Haploidentical HSCT, Zoledronate Study in Children and Adolescents of 177Lu-DOTATATE (Lutatheraยฎ) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). NCT06607692Phase 1, Phase 21 site๐Ÿ“ Boadilla del Monte Fundaciรณn de investigaciรณn HM ยท Tests: Olaparib; 177Lu-DOTATATE Feasibility Study of Prolonged Administration of Naxitamab, Irinotecan, and Temozolomide for Patients With Relapsed or Refractory Neuroblastoma NCT07027748Phase 12 sites๐Ÿ“ Boston๐Ÿ“ Boston Steven DuBois, MD ยท Tests: Naxitamab, Irinotecan, Temozolomide, Sargramostim granulocyte-macrophage colony stimulating factor Phase I Study of Becotatug Vedotin for Safety and Efficacy in EGFR-Positive Pediatric Relapsed/Refractory or Metastatic Solid Tumors NCT07584499Phase 11 site๐Ÿ“ Guangzhou Sun Yat-sen University ยท Tests: Becotatug Vedotin TAA06 Injection in the Treatment of Patients With B7-H3-positive Relapsed/ Refractory Neuroblastoma NCT05562024Phase 12 sites๐Ÿ“ Jinan๐Ÿ“ Tianjin PersonGen BioTherapeutics (Suzhou) Co., Ltd. ยท Tests: T cell injection targeting B7-H3 chimeric antigen receptor Chemoimmunotherapy Combined With Autologous NK Cell Therapy for Pediatric Patients With Refractory and Relapsed High-Risk Neuroblastoma and Ganglioneuroblastoma NCT07375563Phase 31 site๐Ÿ“ Moscow Federal Research Institute of Pediatric Hematology, Oncologโ€ฆ ยท Tests: Dinutuximab beta, temozolomide, irinotecan, autologous NK cell, irinotecan, temozolomide, dinutuximab beta, NK-cell proโ€ฆ Safety, Tolerability, and Preliminary Efficacy of [211At]MABG in Patients With Relapsed or Refractory Neuroblastoma NCT07767630EARLY Phase 11 site๐Ÿ“ Chengdu Sichuan University ยท Tests: [211At]MABG Clinical Analysis of Naxitamab (hu3F8) in the Treatment of Pediatric High Risk or Refractory/ Relapsed Neuroblastoma NCT06013618Phase 21 site๐Ÿ“ Guangzhou Sun Yat-Sen University Cancer Center ยท Tests: Naxitamab monotherapy, GM-CSF, Irinotecan, Temozolomide, Naxitamab in combination therapy Clinical Trial of GAIA-102 for Refractory/Relapse Neuroblastomas and Other Malignant Pediatric Solid Tumors NCT05608148Phase 11 site๐Ÿ“ Fukuoka Kyushu University ยท Tests: Biological, Biological, Biological, Biological NANT 2021-01 Phase II STING (Sequential Temozolomide, Irinotecan, NK Cells and GD2 mAb) Trial NCT06450041Phase 213 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ Aurora New Approaches to Neuroblastoma Therapy Consortium ยท Tests: Universal Donor (UD) TGFฮฒi NK Cells, Temozolomide, Irinotecan, Dinutuximab, GM-CSF Safety & Efficacy of IR-101 in Relapsed/Refractory Neuroblastoma NCT07067346EARLY Phase 12 sites๐Ÿ“ Chengdu๐Ÿ“ Chengdu Sichuan University ยท Tests: IR-101 Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid Tumors NCT06625190Phase 1, Phase 21 site๐Ÿ“ Gainesville University of Florida ยท Tests: Miltenyi CliniMACS Prodigy ยฎ system, Zoledronic acid Allogeneic Expanded Gamma Delta T Cells With GD2 Chemoimmunotherapy in Relapsed /Refractory Neuroblastoma or Refractory/ Relapsed Osteosarcoma NCT05400603Phase 11 site๐Ÿ“ Atlanta Emory University ยท Tests: Ex Vivo Expanded Allogeneic ฮณฮด T Cells in Combination with Dinutuximab, Temozolomide, Irinotecan and Zoledronate Eflornithine (DFMO) and AMXT 1501 for Neuroblastoma, CNS Tumors, and Sarcomas NCT06465199Phase 1, Phase 214 sites๐Ÿ“ Birmingham๐Ÿ“ Little Rock๐Ÿ“ Hartford Milton S. Hershey Medical Center ยท Tests: Eflornithine (DFMO), AMXT 1501 Dicaprate Quadruple Immunotherapy for Neuroblastoma NCT05754684Phase 21 site๐Ÿ“ Hong Kong Hong Kong Children's Hospital ยท Tests: Natural killer cell, Dinutuximab beta, Interleukin-2, Granulocyte-Macrophage Colony-Stimulating Factor, Spironolactone Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma NCT03721068Phase 12 sites๐Ÿ“ Atlanta๐Ÿ“ Chapel Hill UNC Lineberger Comprehensive Cancer Center ยท Tests: iC9.GD2.CAR.IL-15 T-cells, Cyclophosphamide, Fludarabine Immunotherapy With Dinutuximab Beta in Combination With Chemotherapy for the Treatment of Patients With Primary Neuroblastoma Refractory to Standard Therapy and With Relapsed or Progressive Disease NCT05272371Phase 11 site๐Ÿ“ Krakow Jagiellonian University ยท Tests: Chemoimmunotherapy (Dinutuximab beta in combination with chemotherapy) B7-H3.CD28Z.CART in Solid Tumors NCT07358260Phase 11 site๐Ÿ“ Boston Robbie Majzner ยท Tests: B7-H3.CD28Z.CART, Fludarabine, Cyclophosphamide Safety and Efficacy of CAR-T Cell Therapy for Relapsed/refractory Neuroblastoma and Desmoplastic Small Round Cell Tumors: a Single-arm, Open-label Trial. NCT06836505Phase 1, Phase 23 sites๐Ÿ“ Guangzhou๐Ÿ“ Dongguan๐Ÿ“ Shanghai Sun Yat-Sen University Cancer Center ยท Tests: CART therapy NKG2D.Zeta-NK Cell Conditioning With C7R.GD2.CAR-T Cells for Patients With Relapsed or Refractory Osteosarcoma or Neuroblastoma NCT07211737Phase 11 site๐Ÿ“ Houston Baylor College of Medicine ยท Tests: i15.NKG2D.zeta NK cells and C7R.GD2.CARTs cells, i15.NKG2D.zeta NK cells and C7R.GD2.CARTs cells, i15.NKG2D.zeta NK celโ€ฆ A Phase II Study With a Safety Run-In of the Addition of N-803 to a Chemoimmunotherapy Backbone for the Treatment of Patients With Relapsed or Refractory Neuroblastoma NCT07085338Phase 25 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Ann Arbor St. Jude Children's Research Hospital ยท Tests: Temozolomide, Irinotecan, hu14.18K322A, N803, Sargramostim Tipifarnib and Naxitamab for Relapsed/Refractory Neuroblastoma NCT06540963Phase 212 sites๐Ÿ“ Little Rock๐Ÿ“ Hartford๐Ÿ“ Miami Giselle Sholler ยท Tests: Tipifarnib, Naxitamab Study of hALK.CAR T Cells for Patients With Relapsed/Refractory High-risk Neuroblastoma NCT06803875Phase 1, Phase 22 sites๐Ÿ“ Boston๐Ÿ“ Boston Roberto Chiarle ยท Tests: Autologous hALK.CAR T cells PEEL-224, Vincristine and Temozolomide in Pediatric Solid Tumors NCT06721689Phase 1, Phase 27 sites๐Ÿ“ Los Angeles๐Ÿ“ San Francisco๐Ÿ“ Boston Theodore Laetsch ยท Tests: PEEL-224, Vincristine, Temozolomide (TMZ) Autologous B7-H3 Chimeric Antigen Receptor T Cells in Relapsed/Refractory Solid Tumors NCT06500819Phase 11 site๐Ÿ“ Palo Alto Stanford University ยท Tests: B7-H3CART Dose (Intravenous) Phase II Study of Chidamide-Dinutuximab Beta-Irinotecan-Temozolomide for Refractory/Relapsed Neuroblastoma in Children NCT07318831Phase 21 site๐Ÿ“ Tianjin Tianjin Medical University Cancer Institute and Hospital ยท Tests: Chidamide Combined with Dinutuximab Beta, Irinotecan, and Temozolomide 177Lutetium-DOTATATE in Children With Primary Refractory or Relapsed High-risk Neuroblastoma NCT04903899Phase 25 sites๐Ÿ“ Copenhagen๐Ÿ“ Vilnius๐Ÿ“ Utrecht Jakob Stenman ยท Tests: 177Lu-DOTATATE Selective Antigen Specific T Cells and CAR T Cells in Subjects With Relapsed/Refractory Embryonal Tumors (SABRE) NCT07172958Phase 12 sites๐Ÿ“ Washington D.C.๐Ÿ“ Washington D.C. Children's National Research Institute ยท Tests: Selective Antigen Specific dTฮฒRII-expressing T cells combined with B7-H3 CAR T cells Phase I Trial of rhIL-15 Plus Dinutuximab Plus Irinotecan/Temozolomide for Children and Young Adults With Relapsed/Refractory Neuroblastoma NCT06995872Phase 11 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: rhIL-15, Dinituximab, Temozolomide, Irinotecan Hydrochloride Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors NCT06541262Phase 1, Phase 224 sites๐Ÿ“ Birmingham๐Ÿ“ Phoenix๐Ÿ“ Oakland Milton S. Hershey Medical Center ยท Tests: Silmitasertib, Irinotecan, Temozolomide, Vincristine
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