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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Refractory Acute Myeloid Leukemia (AML)

A Study to Investigate the Safety and Tolerability of Ziftomenib in Combination With Venetoclax/Azacitidine, Venetoclax, 7+3, or 7+3+Quizartinib in Patients With AML NCT05735184Phase 144 sites๐Ÿ“ Phoenix๐Ÿ“ La Jolla๐Ÿ“ Los Angeles Kura Oncology, Inc. ยท Tests: Ziftomenib, Venetoclax, Azacitidine, Daunorubicin, Cytarabine A Phase Ib Study of APG-115 Single Agent or in Combination With Azacitidine or Cytarabine in Patients With AML and MDS. NCT04275518Phase 114 sites๐Ÿ“ Beijing๐Ÿ“ Guangzhou๐Ÿ“ Guangzhou Ascentage Pharma Group Inc. ยท Tests: APG-115, Azacitidine, Cytarabine Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors NCT02508038Phase 11 site๐Ÿ“ Madison University of Wisconsin, Madison ยท Tests: TCRฮฑฮฒ+/CD19+ depleted Haploidentical HSCT, Zoledronate A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias NCT06994676Phase 111 sites๐Ÿ“ Duarte๐Ÿ“ Palo Alto๐Ÿ“ Tampa Crossbow Therapeutics, Inc. ยท Tests: CBX-250 Sorafenib Relapase Prophylaxis After HCT With PTBCy Regimen NCT06532084Phase 21 site๐Ÿ“ Saint Petersburg St. Petersburg State Pavlov Medical University ยท Tests: Sorafenib CPX-351 and Ivosidenib for the Treatment of IDH1 Mutated Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome NCT04493164Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Ivosidenib, Liposome-encapsulated Daunorubicin-Cytarabine CAV Regimen for R/R AML NCT05657639Phase 21 site๐Ÿ“ Suzhou The First Affiliated Hospital of Soochow University ยท Tests: CAV Regimen, MEC Regimen CD70-CAR-NK Cell Therapy for T Cell Lymphoma and Acute Myeloid Leukemia NCT06696846Phase 11 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: CD70 CAR-NK A Long-term Follow-up Study of Patients With ARD103 CAR-T Cell Therapies NCT06906380n/a3 sites๐Ÿ“ Charlotte๐Ÿ“ Winston-Salem๐Ÿ“ Houston ARCE Therapeutics, Inc. ยท Tests: Non interventional study Safety and Efficacy of Avapritinib in Relapsed or Refractory Pediatric CBF-AML With KIT Mutation NCT06316960Phase 212 sites๐Ÿ“ Hefei๐Ÿ“ Hefei๐Ÿ“ Guangzhou Children's Hospital of Soochow University ยท Tests: Avapritinib, Azacitidine Injection, Decitabine Injection, Idarubicin Hydrochloride, Cytarabine SupCD7 CART for Relapsed or Refractory CD7 Positive Hematologic Malignancies NCT07153068Phase 1, Phase 21 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: supCD7 CART cells A Clinical Study to Evaluate the Safety and Efficacy of CLL1 and CD38 Dual-Target CAR-T Cell Injection in the Treatment of Relapsed or Refractory Acute Myeloid Leukemia NCT06880354Phase 11 site๐Ÿ“ Tianjin Institute of Hematology & Blood Diseases Hospital, China ยท Tests: CLL1 and CD38 Dual-Target CAR-T Cell Injection Eganelisib as Monotherapy and in Combination With Cytarabine in Relapsed/Refractory AML/HR-MDS and in Combination With Azacitidine in Previously Untreated HR-MDS NCT06533761Phase 112 sites๐Ÿ“ Duarte๐Ÿ“ Aurora๐Ÿ“ Tampa Stelexis BioSciences ยท Tests: Eganelisib, Eganelisib in combination with cytarabine, Eganelisib in combination with azacitidine, Azacitadine (AZA) Niclosamide in Pediatric Patients With Relapsed and Refractory AML NCT05188170Phase 11 site๐Ÿ“ Palo Alto Stanford University ยท Tests: Niclosamide Cladribine, Idarubicin, Cytarabine, and Quizartinib in Treating Patients With Newly Diagnosed, Relapsed, or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome NCT04047641Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Cladribine, Cytarabine, Idarubicin, Quizartinib Quizartinib, Decitabine, and Venetoclax in Treating Participants With Untreated or Relapsed Acute Myeloid Leukemia or High Risk Myelodysplastic Syndrome NCT03661307Phase 1, Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Decitabine, Quizartinib, Venetoclax Venetoclax Basket Trial for High Risk Hematologic Malignancies NCT05292664Phase 15 sites๐Ÿ“ San Francisco๐Ÿ“ Aurora๐Ÿ“ Atlanta Andrew E. Place, MD ยท Tests: Venetoclax, Azacitidine, Cytarabine, Methotrexate, Hydrocortisone Treatment With ABT-199 (Venetoclax) and Purine Analogues in Relapsed/Refractory Acute Myeloid Leukemia NCT05506332Phase 12 sites๐Ÿ“ Edegem๐Ÿ“ Roeselare University Hospital, Antwerp ยท Tests: Venetoclax, 6-mercaptopurine Efficacy and Safety of CD19-CAR.p40-T in Patients With Relapsed/Refractory CD19-Positive Hematologic Malignancies NCT07584889Phase 1, Phase 21 site๐Ÿ“ Shenzhen Shenzhen University General Hospital ยท Tests: CAR-T cell Off-the-shelf CD123 CAR-NK for R/R AML NCT06201247EARLY Phase 11 site๐Ÿ“ Beijing Peking University People's Hospital ยท Tests: JD123 injection Study of Oral PCLX-001 in R/R Acute Myeloid Leukemia NCT06613217Phase 11 site๐Ÿ“ Houston Pacylex Pharmaceuticals ยท Tests: zelenirstat Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer NCT01137643n/a1 site๐Ÿ“ Chapel Hill UNC Lineberger Comprehensive Cancer Center ยท Tests: biologic sample preservation procedure, cytology specimen collection procedure A Study of BTX-A51 in People With Relapsed or Refractory Acute Myeloid Leukemia or High-Risk Myelodysplastic Syndrome NCT04243785Phase 13 sites๐Ÿ“ Duarte๐Ÿ“ New York๐Ÿ“ Houston Edgewood Oncology Inc. ยท Tests: BTX-A51, Azacitidine HEC73543 Versus Salvage Chemotherapy in R/R FLT3-ITD AML NCT05586074Phase 31 site๐Ÿ“ Hanzhou Sunshine Lake Pharma Co., Ltd. ยท Tests: Clifutinib, LoDAC, Azacitidine, Decitabine, Ara-CยฑIDA Study of C6 Ceramide NanoLiposome (CNL) in Patients With Relapsed/Refractory Acute Myeloid Leukemia NCT04716452Phase 11 site๐Ÿ“ Charlottesville Keystone Nano, Inc ยท Tests: Ceramide NanoLiposome (Ceraxa) Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS NCT07532824Phase 1, Phase 22 sites๐Ÿ“ Prague๐Ÿ“ Prague Institute of Hematology and Blood Transfusion, Czech Republโ€ฆ ยท Tests: Proton Total Marrow Irradiation Clinical Study of LILRA6 CAR-T for the Treatment of R/R Acute Myeloid Leukemia NCT07263906Phase 11 site๐Ÿ“ Hangzhou Second Affiliated Hospital, Zhejiang University, School of โ€ฆ ยท Tests: Anti-LILRA6 CAR-T cells Ziftomenib + Mezigdomide in Adolesc. and Adults w/ R/R AML NCT07355335Phase 12 sites๐Ÿ“ Boston๐Ÿ“ Boston Massachusetts General Hospital ยท Tests: Ziftomenib, Mezigdomide A Study of CHM-029 in Participants With NPM1 Mutated, KMT2A or NUP98 Rearranged AML NCT07751991Phase 15 sites๐Ÿ“ Duarte๐Ÿ“ New Haven๐Ÿ“ Grand Rapids Charm Therapeutics ยท Tests: CHM-029 Study on the Efficacy and Safety of the TmBU Conditioning Regimen in High-risk or Relapsed/Refractory Acute Leukemia NCT06816134Phase 21 site๐Ÿ“ Suzhou The First Affiliated Hospital of Soochow University ยท Tests: TmBU conditioning Regimen, mBUCY conditioning regimen
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