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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Relapsed/Refractory Large B-Cell Lymphoma

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy NCT07188558Phase 336 sites📍 Gilbert📍 Scottsdale📍 Scottsdale Lyell Immunopharma, Inc. · Tests: rondecabtagene autoleucel, axicabtagene ciloleucel, lisocabtagene maraleucel Epcoritamab Plus Ibrutinib for the Treatment of Relapsed or Refractory Aggressive B-Cell Non-Hodgkin Lymphoma NCT06536049Phase 1, Phase 23 sites📍 Minneapolis📍 Columbus📍 Richmond Yazeed Sawalha · Tests: Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography, Epcoritamab Study to Evaluate Combined Treatment of Daratumumab, Bortezomib and Dexamethasone in PBL Patients. NCT04915248Phase 218 sites📍 Ancona📍 Aviano📍 Florence Fondazione Italiana Linfomi - ETS · Tests: Daratumumab, Bortezomib, Dexamethasone UB-VV400 in Combination With Rapamycin in Relapsed or Refractory B-cell Malignancies NCT06743503Phase 12 sites📍 Nanjing📍 Tianjin Nanjing IASO Biotechnology Co., Ltd. · Tests: UB-VV400, Rapamycin Study to Evaluate the Effectiveness of Tafasitamab in Combination With Lenalidomide Followed by Tafasitamab Monotherapy in Relapsed or Refractory Diffuse Large B-cell Lymphoma Non-transplant Eligible Patients in Italy (PRO-MIND) NCT06299553n/a1 site📍 Milan Incyte Biosciences Italy S.r.l Odronextamab for Relapsed and Refractory Large B-cell Lymphomas Before CAR-T NCT06784726Phase 21 site📍 Seattle University of Washington · Tests: Odronextamab, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Chimeric Antigen Receptor T-Cell Ther… Evaluate Optimization of CRS Profile for Glofit Monotherapy and Glofit+GemOx in R/R Aggressive B-NHL NCT06806033Phase 253 sites📍 Anchorage📍 Clovis📍 Fullerton Hoffmann-La Roche · Tests: Obinutuzumab, Glofitamab, Gemcitabine, Oxaliplatin Response-adaptive to Epcoritamab In First Relapse: Study to Evaluate the Efficacy of Eptoritamab in Patients With Relapse/Refractory Large B Cell Lymphoma NCT07126236Phase 219 sites📍 Seville📍 Zaragoza📍 Palma de Mallorca Grupo Español de Linfomas y Transplante Autólogo de Médula … · Tests: Epcoritamab, Epcoritamab, tafasitamab and lenalidomide NT-I7 (Efineptakin Alfa), a Long-acting Human IL-7, Post-Axicabtagene Ciloleucel or Post-Lisocabtagene Maraleucel in Subjects With Relapsed/Refractory Large B-cell Lymphoma NCT07052305Phase 11 site📍 St Louis Washington University School of Medicine · Tests: NT-I7, CAR T-cell therapy Testing the Effectiveness of a Combination Targeted Therapy (ViPOR) for Patients With Relapsed and/or Refractory Aggressive B-cell Lymphoma NCT06649812Phase 2114 sites📍 Tucson📍 Tucson📍 Los Angeles National Cancer Institute (NCI) · Tests: Biopsy Procedure, Biospecimen Collection, Bone Marrow Aspiration, Bone Marrow Biopsy, Computed Tomography Efficacy and Safety of MB-CART2019.1 vs. SoC in Lymphoma Patients NCT04844866Phase 251 sites📍 Graz📍 Innsbruck📍 Linz Miltenyi Biomedicine GmbH · Tests: MB-CART2019.1, Standard of Care Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer NCT01137643n/a1 site📍 Chapel Hill UNC Lineberger Comprehensive Cancer Center · Tests: biologic sample preservation procedure, cytology specimen collection procedure Ascorbic Acid and Chemotherapy for the Treatment of Relapsed or Refractory Lymphoma, CCUS, and Chronic Myelomonocytic Leukemia NCT03418038Phase 24 sites📍 Mankato📍 Rochester📍 Eau Claire Mayo Clinic · Tests: Ascorbic Acid, Carboplatin, Cisplatin, Cytarabine, Dexamethasone A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies. NCT06542250Phase 1, Phase 231 sites📍 La Jolla📍 Boston📍 Rochester AstraZeneca · Tests: AZD5492 Hyperfractionated Dual Equivalent Fractionated Radiation Therapy NCT06898905NA1 site📍 New Haven Yale University · Tests: Bridging Radiation Therapy Drug-Eluting Bead-Based Transarterial Chemoembolization (DEB-TACE) as a Local Salvage Therapy for Large Lesions in Relapsed and Refractory Diffuse Large B-Cell Lymphoma NCT07198230n/a1 site📍 Fuzhou Ting YANG Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas NCT07478848Phase 11 site📍 Philadelphia Abramson Cancer Center at Penn Medicine · Tests: Vancomycin 125mg, Radiation Therapy, CAR-T T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL) NCT06343311Phase 1, Phase 25 sites📍 Sacramento📍 Cleveland📍 Portland Estrella Immunopharma, Inc. · Tests: EB103 Low Dose Epcoritamab Plus GemOx in R/R DLBCL NCT07451652Phase 21 site📍 Monterrey Hospital Universitario Dr. Jose E. Gonzalez · Tests: Epcoritamab, Gemcitabine (1000 mg/m2), Oxaliplatin Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL NCT06104592Phase 21 site📍 Tampa H. Lee Moffitt Cancer Center and Research Institute · Tests: Comprehensive Ablative Bridging Irradiation (CABI), Chimeric Antigen Receptor T-Cell Therapy An Open-label, Single-arm Study of JWCAR201 in the Treatment of Relapsed or Refractory Diffuse Large B-cell Lymphoma NCT06517004Phase 11 site📍 Shanghai Fudan University · Tests: JWCAR201 Immune Cell Therapy (CAR-T) for the Treatment of Patients With HIV and B-Cell Non-Hodgkin Lymphoma NCT05077527Phase 17 sites📍 Duarte📍 Chicago📍 New York AIDS Malignancy Consortium · Tests: Axicabtagene Ciloleucel, Cyclophosphamide, Fludarabine A Phase I Trial to Establish the Safety and Maximum Tolerated Dose of High-affinity Autologous BCMA-targeting Chimeric Antigen Receptor (CAR) T-cells in Patients With Relapsed and Refractory B-cell Malignancies NCT05836896Phase 11 site📍 Dresden Technische Universität Dresden · Tests: MDC-CAR-BCMA001 (BCMA directed CAR T-cells) A Study of Rocbrutinib Combined With R-GemOx in Patients With Relapsed or Refractory Diffuse Large B-cell Lymphoma NCT07570017Phase 12 sites📍 Guangzhou📍 Shanghai Guangzhou Lupeng Pharmaceutical Company LTD. · Tests: Rocbrutinib, R-GemOx A Multicenter Observational Study to Understand the Clinical Characteristics, Treatment Patterns and Access to Novel Therapies of Patients With Diffuse Large B-Cell Lymphoma in the MEA Region NCT07065344n/a21 sites📍 Al Mansurah📍 Alexandria📍 Cairo AstraZeneca Study of CAR-T Therapy in Older Patients NCT04300998n/a1 site📍 New York Memorial Sloan Kettering Cancer Center · Tests: Activities of Daily Living/ADLs, Instrumental Activity of Daily Living, Timed Up and Go, Cognition, Geriatric Depressio… A Phase III Study of HMPL-760 Plus R-GemOx VS Placebo Plus R-GemOx in Relapsed/Refractory DLBCL NCT07409428Phase 350 sites📍 Shanghai📍 Baoding📍 Beijing Hutchmed · Tests: HMPL-760, HMPL-760 Placebo, R-GemOx A Study of NX-2127 in Adults With Relapsed/Refractory B-cell Malignancies NCT04830137Phase 116 sites📍 Duarte📍 Orange📍 San Francisco Nurix Therapeutics, Inc. · Tests: NX-2127 Lymphodepletion With Low Dose Total Body Irradiation Before Standard of Care Tisagenlecleucel for the Treatment of Relapsed and Recurrent Large B-cell Lymphoma NCT07676877Phase 11 site📍 Columbus Nathan Denlinger · Tests: Biospecimen Collection, Computed Tomography, Cyclophosphamide, Fludarabine, Leukapheresis Pembro Plus CAR T-cell Therapy in R/R in PMBCL NCT05934448Phase 22 sites📍 Boston📍 New York Jennifer Crombie, MD · Tests: Pembrolizumab, Lymphodepletion Chemotherapy, Chimeric Antigen Receptor (CAR) Therapy Infusion, Leukapheresis
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