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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Severe Aplastic Anemia

CD7 CAR-T Bridging to alloHSCT for Severe Aplastic Anemia NCT06633328EARLY Phase 11 site📍 Hanzhou Zhejiang University · Tests: CD7 CAR-T cells injection, Allogeneic hematopoietic stem cell transplantation A Multicenter Access and Distribution Protocol for Unlicensed Cryopreserved Cord Blood Units (CBUs) NCT01351545n/a142 sites📍 Birmingham📍 Gilbert📍 Phoenix Center for International Blood and Marrow Transplant Resear… · Tests: A multicenter access and distribution protocol for unlicensed cryopreserved cord blood units (CBUs) Enhancing the Clinical Management of CMF Through a National Pediatric and Adult Network Based on Biological and Genetic Data NCT07877727n/a4 sites📍 Avellino📍 Genova📍 Naples Istituto Giannina Gaslini Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer NCT01137643n/a1 site📍 Chapel Hill UNC Lineberger Comprehensive Cancer Center · Tests: biologic sample preservation procedure, cytology specimen collection procedure Reduced Intensity Conditioning for Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT NCT01962415Phase 21 site📍 Pittsburgh Paul Szabolcs · Tests: Hydroxyurea, Alemtuzumab, Fludarabine, Melphalan, Thiotepa Phase I/II Study of Anti-CD38 Monoclonal Antibody in Refractory Severe Aplastic Anemia NCT07714512Phase 1, Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Isatuximab CD7 CAR T Cells (RD13-02) in the Treatment of Relapsed/Refractory Severe Aplastic Anemia NCT06622694Phase 11 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: RD13-02 Haploidentical HCT for Severe Aplastic Anemia NCT04558736Phase 21 site📍 Memphis St. Jude Children's Research Hospital · Tests: Anti-Thymocyte Globulin (Rabbit), Fludarabine, Cyclophosphamide, Mesna, G-CSF Natural History of Acquired and Inherited Bone Marrow Failure Syndromes NCT05012111n/a1 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) AlloSCT for Malignant and Non-malignant Hematologic Diseases Utilizing Alpha/Beta T Cell and CD19+ B Cell Depletion NCT04099966Phase 21 site📍 Valhalla Mitchell Cairo · Tests: alpha beta depletion Data Collection Study of Patients With Non-Malignant Disorders Undergoing UCBT, BMT or PBSCT With RIC NCT04528355n/a1 site📍 Pittsburgh Paul Szabolcs · Tests: data collection T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias NCT03653338Phase 1, Phase 21 site📍 Pittsburgh Paul Szabolcs · Tests: CD3/CD19 depleted leukocytes, CD45RA depleted leukocytes, Hydroxyurea, Rituximab, Alemtuzumab TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Non-Malignant Hematological Disorders in Children NCT04356469Phase 21 site📍 St. Petersburg Johns Hopkins All Children's Hospital · Tests: Haploidentical Hematopoietic Cell Transplantation HPC Offered for PRESERVE Expansion NCT07145411n/a4 sites📍 Birmingham📍 Detroit📍 Columbus Ossium Health, Inc. · Tests: Bone Marrow Transplant with Ossium's HPC, Marrow (bone marrow recovered from deceased organ and tissue donors) Alpha/Beta TCD HCT in Patients With Inherited BMF Disorders NCT03579875Phase 21 site📍 Minneapolis Masonic Cancer Center, University of Minnesota · Tests: Total Body Irradiation (TBI) (Plan 1), Cyclophosphamide (CY) (Plan 1), Fludarabine (FLU), Methylprednisolone (MP), Dono… Nonmyeloablative Stem Cell Transplant in Children With Sickle Cell Disease and a Major ABO-Incompatible Matched Sibling Donor NCT03214354Phase 21 site📍 Calgary University of Calgary · Tests: Alemtuzumab, Total Body Irradiation, Sirolimus Unrelated Umbilical Cord Blood Transplantation for Severe Aplastic Anemia and Hypo-plastic MDS Using CordIn(TM), Umbilical Cord Blood-Derived Ex Vivo Expanded Stem and Progenitor Cells to Expedite Engraftment and Improve Transplant Outcome NCT03173937Phase 1, Phase 21 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) · Tests: Omidubicel (former CordIn), Miltenyi CliniMACS(R) CD34 Reagent System Early Initiation of Oral Therapy With Cyclosporine and Eltrombopag for Treatment Naive Severe Aplastic Anemia (SAA) NCT04304820Phase 21 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) · Tests: Eltrombopag, Cyclosporine, Horse-Anti-thymocyte-Globulin MT2023-20: Hematopoietic Cell Transplant With Reduced Intensity Conditioning and Post-transplant Cyclophosphamide for Severe Aplastic Anemia and Other Forms of Acquired Bone Marrow Failure. NCT06412497Phase 21 site📍 Minneapolis Masonic Cancer Center, University of Minnesota · Tests: Rituximab, Rabbit ATG, Cyclophosphamide, Fludarabine, Total Body Irradiation Haplo-identical Transplantation for Severe Aplastic Anemia, Hypo-plastic MDS and PNH Using Peripheral Blood Stem Cells and Post-transplant Cyclophosphamide for GVHD Prophylaxis NCT03520647Phase 21 site📍 Bethesda National Heart, Lung, and Blood Institute (NHLBI) · Tests: Cyclophosphamide, Peripheral Blood Stem Cells Peripheral Blood Versus Bone Marrow Plus Peripheral Blood Grafts for Haploidentical Transplantation in Severe Aplastic Anemia NCT07629947NA1 site📍 Beijing Peking University People's Hospital · Tests: G-CSF-Primed Peripheral Blood Stem Cell Graft, G-CSF-Primed Bone Marrow Plus Peripheral Blood Stem Cell Graft Clinical Trial of Upfront Haploidentical or Unrelated Donor BMT to Restore Normal Hematopoiesis in Aplastic Anemia NCT06517641Phase 225 sites📍 Birmingham📍 Duarte📍 Los Angeles Medical College of Wisconsin · Tests: Haploidentical donor bone marrow transplant, Unrelated donor bone marrow transplant Clinical Study on Modified Allogeneic Hematopoietic Stem Cell Transplantation Regimen for Severe Aplastic Anemia NCT06378060Phase 21 site📍 Kunming Hematology department of the 920th hospital · Tests: Modified transplantation system Rituximab for Serious Aplastic Anemia With Platelet Transfusion Refractoriness NCT06254560Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Rituximab Investigation of the Genetics of Hematologic Diseases NCT02720679n/a1 site📍 Memphis St. Jude Children's Research Hospital Dose-attenuated IST and Hetrombopag in Elderly (≥65 Years) Patients With Severe Aplastic Anemia NCT07010237Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Dose-attenuated IST and Hetrombopag A Reduced-Intensity Conditioning Regimen (Cyclophosphamide, Pentostatin, Anti-thymocyte Globulin) Followed by Haploidentical Hematopoietic Stem Cell Transplant for the Treatment of Patients With Refractory or Recurrent Severe Aplastic Anemia NCT05757310Phase 11 site📍 Duarte City of Hope Medical Center · Tests: Anti-Thymocyte Globulin, Biospecimen Collection, Bone Marrow Aspirate, Bone Marrow Biopsy, Cyclophosphamide Reduced Dose of Cyclophosphamide Combined With Standard Immunosuppressive Therapy to Treat Severe Aplastic Anemia NCT06695741Phase 21 site📍 Tianjin Institute of Hematology & Blood Diseases Hospital, China · Tests: Reduced dose of cyclophosphamide combined with standard immunosuppressive therapy A Novel Conditioning Regimen for Haplo-HSCT in Older Patients With SAA NCT07586735n/a1 site📍 Beijing Peking University People's Hospital · Tests: BFCA conditiong regimen Haploidentical Bone Marrow Transplant With Post-Transplant Cyclophosphamide for Patients With Severe Aplastic Anemia NCT02828592Phase 22 sites📍 Atlanta📍 Atlanta Northside Hospital, Inc. · Tests: Fludarabine, Cyclophosphamide, Total Body Irradiation, Rabbit ATG, Cyclophosphamide
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