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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Severe Obesity

Does Semaglutide Improve Depressive Symptoms in Patients With Major Depressive Disorder and Overweight or Obesity NCT07136714Phase 41 site📍 Hillerød Nordsjaellands Hospital · Tests: Semaglutide Injectable Product, Placebo Bougie Sleeve Trial NCT02937649NA12 sites📍 Boulogne-Billancourt📍 Caen📍 Clamart Assistance Publique - Hôpitaux de Paris · Tests: Laparoscopic sleeve gastrectomy using 48-Fr bougie, Laparoscopic sleeve gastrectomy using standard care bougie Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a1 site📍 Sioux Falls Sanford Health Stool Analysis After Sleeve Gastrectomy vs Gastric Bypass NCT07461610n/a1 site📍 Cairo Cairo University · Tests: Laparoscopic Sleeve Gastrectomy, Mini Gastric Bypass, Roux-en-Y Gastric Bypass A Study of IBI362 in Chinese Subjects With Obstructive Sleep Apnea and BMI≥28 kg/m2 NCT06931028Phase 31 site📍 Beijing Innovent Biologics (Suzhou) Co. Ltd. · Tests: placebo, IBI362 Impact of Bariatric Surgery on Female Sexual Function and Sex Hormones NCT07446972n/a1 site📍 Cairo Cairo University · Tests: Sleeve Gastrectomy, Gastric Bypass Real-World Effects of MC4R Agonist Therapy in BBS and Severe Genetic Obesity NCT07674290Phase 41 site📍 Essen Tom Hühne · Tests: Setmelanotide Comparison of Hormonal Response to a Mixed-Meal Tolerance Test After Laparoscopic Roux-en-Y Gastric Bypass Versus Laparoscopic Sleeve Gastrectomy With Duodenojejunal Bypass in Patients With Super Morbid Obesity NCT07747779NA1 site📍 Pathum Wan Chulalongkorn University · Tests: Sleeve gastrectomy with duodenojejunal bypass, Roux-en-Y gastric bypass Effect of Limb Length Ratio on Roux-en-Y Gastric Bypass Outcomes (CLIMB II Study) NCT06293703NA1 site📍 Cleveland Salvador Navarrete · Tests: Surgery Optimizing Portal Hypertension With TIPS and Interval Metabolic Surgery for Advanced Liver Disease NCT07058155Phase 41 site📍 Cleveland The Cleveland Clinic · Tests: Transjugular Intrahepatic Portosystemic Shunt (TIPS), Sleeve Gastrectomy, Anti-Obesity Pharmacotherapy (Class Effect), … Early Discharge With Hospital-at-Home After Bariatric Surgery and Economic Evaluation. NCT07782281n/a1 site📍 Sabadell Corporacion Parc Tauli The Bioavailability and Effect on Pouch pH of Esomeprazole After Gastric Bypass NCT05320796Phase 41 site📍 Schlieren Prof Urs Zingg · Tests: upper endoscopy Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity. NCT01998750n/a2 sites📍 Boston📍 New York Columbia University Longitudinal Study of the Psychological Impact of Bariatric Surgery NCT07780058n/a2 sites📍 Alcoy📍 Alicante University of Alicante A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients NCT03472157NA1 site📍 Lille University Hospital, Lille · Tests: Lifestyle therapy, Bariatric surgery The Effect of Mediterranean Diet and Mindfulness Eating on Depression Severity in People With Obesity and Major Depressive Disorder NCT06621394NA1 site📍 Stuttgart University Hospital Tuebingen · Tests: nutritional intervention, Mindful Eating, Attention Control Bariatric Surgery Combined With GLP-1 Receptor Agonists Study NCT07336862Phase 1, Phase 21 site📍 Beijing China-Japan Friendship Hospital · Tests: BS-GLP group, BS group Obesity Cohort : Medical Follow-up of Severe or Morbid Obese Patients Undergoing Bariatric Surgery NCT02310178NA1 site📍 Montpellier University Hospital, Montpellier · Tests: Bariatric surgery RCT Comparing OAGB and Long Limb Roux Gastric Bypass NCT04812132NA1 site📍 Tartu Tartu University Hospital · Tests: One-anastomosis gastric bypass, Long biliary limb Roux gastric bypass Whole Transcriptome Profiling and Metabolic Phenotyping in Children With ROHHAD Syndrome NCT02602769n/a2 sites📍 Boston📍 New York Columbia University · Tests: Transcriptome profiling Changes in the Lipidomic, Immunological and miRNA Profile in Patients Undergoing a Dietary Program or Bariatric Surgery NCT06372015n/a1 site📍 Castellana Grotte Azienda Ospedaliera Specializzata in Gastroenterologia Save… · Tests: Nutritional Approach, Surgery Approach Gastric Recalibration After Endoscopic Sleeve Gastroplasty NCT04945473NA1 site📍 Strasbourg IHU Strasbourg · Tests: Endoscopic placement of additional sutures Determinants of the Long-Term Success of Bariatric Surgery NCT03517072n/a4 sites📍 Arras📍 Boulogne-sur-Mer📍 Lille University Hospital, Lille Impact GLP-1 Agonists Following Bariatric NCT06132477Phase 41 site📍 Columbia University of Missouri-Columbia · Tests: GLP-1 receptor agonist Targeting the Hepatic BMP-SMAD Pathway in Leptin Receptor Deficiency (LEPRD) NCT07833592n/a1 site📍 Novara Azienda Ospedaliero Universitaria Maggiore della Carita Effectiveness of Two Different Body Positions During Facemask Ventilation in Obese Patients NCT06305273NA1 site📍 Toronto Mount Sinai Hospital, Canada · Tests: Head position for face mask ventilation during induction supine, Head position for face mask ventilation during inducti… Metabolic Responses to Bariatric Surgery NCT02024542n/a1 site📍 Sacramento University of California, Davis · Tests: Surgery Induction of Labor in Morbidly Obese Patients NCT06199154EARLY Phase 11 site📍 Baltimore University of Maryland, Baltimore · Tests: Misoprostol Magnetic Resonance Imaging Assessment of Multiorgan Health in Obesity NCT07702825n/a1 site📍 Liverpool Alder Hey Children's NHS Foundation Trust A Multicenter, Randomized, Double-blind, Placebo-controlled Phase III Clinical Study to Evaluate the Efficacy and Safety of HRS9531 Injection in Subjects With Obstructive Sleep Apnea (OSA) and Obesity Who Are on Positive Airway Pressure Ventilation (PAP) Therapy NCT06994650Phase 31 site📍 Beijing Fujian Shengdi Pharmaceutical Co., Ltd. · Tests: HRS9531, Placebo
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