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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Spinal Muscular Atrophy

Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a1 site๐Ÿ“ Sioux Falls Sanford Health Exploring the Physiologic, Pharmacodynamic, and Clinical Responses of Skeletal Muscle in Patients With Spinal Muscular Atrophy Treated With SMN-Directed Therapies NCT06532474n/a1 site๐Ÿ“ Memphis St. Jude Children's Research Hospital A Registry Based Randomized-Controlled Trial of an Upper Limb Exergaming Intervention for Children and Adolescents With Spinal Muscular Atrophy NCT06396325NA5 sites๐Ÿ“ Calgary๐Ÿ“ Vancouver๐Ÿ“ Halifax Maryam Oskoui, MD, MSc, FRCPC, FAAN ยท Tests: Tales from the Magic Keepโ„ข, Usual Care A Study to Learn About the Investigational Drug Rinzimetostat (ORIC-944) in Patients With mCRPC Who Were Previously Treated With Abiraterone Acetate (Himalayas-1) NCT07723248Phase 312 sites๐Ÿ“ Coral Springs๐Ÿ“ Jeffersonville๐Ÿ“ Holland ORIC Pharmaceuticals ยท Tests: Rinzimetostat, Darolutamide, Enzalutamide, Docetaxel A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy NCT07047144Phase 223 sites๐Ÿ“ Phoenix๐Ÿ“ Orange๐Ÿ“ Palo Alto Scholar Rock, Inc. ยท Tests: Apitegromab, Nusinersen, Risdiplam Safety and Tolerability of Low Motoneuron Stimulation Via Transcranial Magnetic Stimulation in Spinal Muscular Atrophy NCT06977269NA1 site๐Ÿ“ Kharkiv Charitable Foundation Children with Spinal Muscular Atrophy ยท Tests: High-frequency repetitive transcranial magnetic stimulation, lumbar puncture A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety in Participants Aged 15 to 60 Years With Spinal Muscular Atrophy (SMA) Who Are Either New to SMA Treatment or Were Previously Treated With Risdiplam NCT07444476Phase 33 sites๐Ÿ“ Palo Alto๐Ÿ“ Norfolk๐Ÿ“ Beijing Biogen ยท Tests: Salanersen A Study to Find Out How Nusinersen is Processed in the Body When Given Through the ThecaFlex DRxโ„ข System in Adult and Pediatric Participants With Spinal Muscular Atrophy (PIERRE-PK) NCT06555419Phase 121 sites๐Ÿ“ Phoenix๐Ÿ“ Orange๐Ÿ“ Palo Alto Biogen ยท Tests: Nusinersen, ThecaFlex DRx System Interfacing With NeuroTechnology to Expand Neural Throughput (INTENT) NCT07521930NA1 site๐Ÿ“ Baltimore Johns Hopkins University ยท Tests: INTENT Neural Interface System Evaluating VM100 Nutritional Supplement for Improving Quality of Life in Duchenne Muscular Dystrophy Patients NCT07766980Phase 21 site๐Ÿ“ Gainesville University of Florida ยท Tests: VM100 Nutritional Supplement Fatigue and Skeletal Muscle Impact in Severe Axial Spondyloarthritis NCT03940911NA1 site๐Ÿ“ Strasbourg University Hospital, Strasbourg, France ยท Tests: Measurement of aerobic exercise on cycloergometer Evaluation of the Reproducibility of a Fatigability Test Fitted to Patients With Spinal Muscular Atrophy NCT06562283NA4 sites๐Ÿ“ Saint-Etienne๐Ÿ“ Lyon๐Ÿ“ Lyon Centre Hospitalier Universitaire de Saint Etienne ยท Tests: Thumb test, Grip test, Quadriceps Intermittent Fatigue test (QIF test)) A Study to Assess the Safety, Tolerability, Efficacy, Pharmacokinetics, and Immunogenicity of Intravenous Administration of ARGX-119 in Pediatric Participants Aged 5 to Less Than 18 Years With Spinal Muscular Atrophy NCT07287982Phase 228 sites๐Ÿ“ Little Rock๐Ÿ“ San Diego๐Ÿ“ Stanford argenx ยท Tests: ARGX-119 IV, Placebo IV Impairments of Neuro-muscular Communication in Motor-Neuron Disease: A Bio-Marker for Early and Personalised Diagnosis NCT05663008n/a1 site๐Ÿ“ Dublin University of Dublin, Trinity College ยท Tests: 128 electrode electroencephalography (EEG), Bipolar surface electromyography (sEMG), High-density electromyography (HD-โ€ฆ Diagnostic Journey, Patient Experience, and Disparities in the Treatment of Spinal Muscular Atrophy (SMA) in the MedStar Health System NCT07223489n/a1 site๐Ÿ“ Washinton Medstar Health Research Institute ยท Tests: Telephone Interview Establishing Walking-related Digital Biomarkers in Rare Childhood Onset Progressive Neuromuscular Disorders NCT06839469n/a3 sites๐Ÿ“ Palo Alto๐Ÿ“ Boston๐Ÿ“ New York Columbia University Invasive Home Ventilation in Denmark NCT07467187n/a1 site๐Ÿ“ Copenhagen Copenhagen University Hospital, Rigshospitalet HABIT-ILE + FST in Children With SMA: Preliminary Effectiveness NCT07488338NA1 site๐Ÿ“ New York Teachers College, Columbia University ยท Tests: Combined Hand-Arm Bimanual Intensive Therapy Including Lower Extremities (HABIT-ILE) + functional strength training (FSโ€ฆ Long Read Analysis in Spinal Muscular Atrophy - LOREASI NCT07332702NA1 site๐Ÿ“ Rouen University Hospital, Rouen ยท Tests: blood sample A Study to Learn About Salanersen's (BIIB115) Effects on Movement and Its Safety When Given Before Symptoms Appear in Babies With Genetically Diagnosed Spinal Muscular Atrophy (SMA) NCT07221669Phase 314 sites๐Ÿ“ Chicago๐Ÿ“ Flower Mound๐Ÿ“ Norfolk Biogen ยท Tests: Salanersen Clinical, Molecular and Imaging Biomarkers in Spinal and Bulbar Muscular Atrophy (SBMA) NCT04944940n/a1 site๐Ÿ“ Bethesda National Institute of Neurological Disorders and Stroke (NIโ€ฆ Sarcopenia and Interlaminar Epidural Steroid Injection Outcomes in Lumbar Spinal Stenosis NCT07855419n/a1 site๐Ÿ“ Istanbul Marmara University Study of an Intrathecal Port and Catheter System for Subjects With Spinal Muscular Atrophy NCT05866419NA21 sites๐Ÿ“ Phoenix๐Ÿ“ Orange๐Ÿ“ Palo Alto Alcyone Therapeutics, Inc ยท Tests: ThecaFlex DRx System Adult SMA Research and Clinical Hub NCT06978985n/a18 sites๐Ÿ“ Birmingham๐Ÿ“ Bristol๐Ÿ“ Cambridge Newcastle-upon-Tyne Hospitals NHS Trust ยท Tests: Risdiplam, Nusinersen Injectable Product Safety and Efficacy Evaluation of GC101 Gene Therapy Via Intrathecal (IT) Injectionin the Treatment of Patients With Type 2 Spinal Muscular Atrophy (SMA) - Phase III NCT06971094Phase 37 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing GeneCradle Inc ยท Tests: GC101 adeno-associated virus injection Gait Analysis Parameter and Upper Limb Evaluation in Adult Patients With Neurological or Metabolic Pathology NCT07136844NA1 site๐Ÿ“ Liรจge Centre Hospitalier Universitaire de Liege ยท Tests: Syde, Dynamometric measurements of muscle strength, The 6-minute walk test (6MWT), The 10-meter test (10MWT), The 4 staโ€ฆ SMAdult - Monitoring of Movement on Spinal Muscular Atrophy NCT07894185NA1 site๐Ÿ“ Liรจge Centre Hospitalier Universitaire de Liege ยท Tests: wearable sensors Evaluation of Safety and Efficacy of Gene Therapy Drug in the Treatment of Spinal Muscular Atrophy (SMA) Type 3 Patients NCT06421831Phase 1, Phase 21 site๐Ÿ“ Beijing GeneCradle Inc ยท Tests: GC101 Clinical Trial of Mexiletine Hydrochloride for Spinal and Bulbar Muscular Atrophy NCT06862596Phase 2, Phase 35 sites๐Ÿ“ Bunkyล City๐Ÿ“ Chiba๐Ÿ“ Sapporo Masahisa Katsuno ยท Tests: Mexiletine hydrochloride, Placebo Study of the Safety and Efficacy of an Adeno-Associated Viral Vector Carrying the SMN Gene After a Single Intravenous Administration of Escalating Doses in Children With Spinal Muscular Atrophy (BLUEBELL) NCT05747261Phase 1, Phase 27 sites๐Ÿ“ Minsk๐Ÿ“ Moscow๐Ÿ“ Moscow Biocad ยท Tests: ANB-004, dose 1, ANB-004, dose 2, ANB-004, dose 3
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