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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Squamous Cell Carcinoma of the Skin

Tumor-Informed ctDNA Testing for MRD Following Treatment of Squamous Cell Carcinoma NCT06606028n/a1 site๐Ÿ“ San Francisco University of California, San Francisco ยท Tests: Blood Specimen Collection, Tumor Tissue Collection, Medical Record Review A Study to Evaluate the Efficacy and Safety of Ifinatamab Deruxtecan (I-DXd) in Subjects With Recurrent or Metastatic Solid Tumors (IDeate-PanTumor02) NCT06330064Phase 1, Phase 2120 sites๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles๐Ÿ“ Whittier Daiichi Sankyo ยท Tests: Ifinatamab deruxtecan Phase 2 Study of Ivonescimab in Patients With Cutaneous Squamous Cell Carcinoma NCT06567314Phase 21 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Ivonescimab Study of GV20-0251 in Participants With Solid Tumor Malignancies NCT07070518Phase 1, Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Shanghai GV20 Therapeutics ยท Tests: GV20-0251 A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-0111 in Patients With Solid Tumors NCT06700070EARLY Phase 11 site๐Ÿ“ Shreveport Pure Biologics S.A. ยท Tests: PBA-0111 Towards Cure Via Only Ultra-short ICB in CSCC NCT06823479Phase 25 sites๐Ÿ“ Maastricht๐Ÿ“ Amsterdam๐Ÿ“ Amsterdam The Netherlands Cancer Institute ยท Tests: Nivolumab, Ipilumimab A Study to Investigate Safety of AZD6750 in Adult Participants With Select Advanced or Metastatic Solid Tumors NCT07115043Phase 1, Phase 213 sites๐Ÿ“ Grand Rapids๐Ÿ“ St Louis๐Ÿ“ Pittsburgh AstraZeneca ยท Tests: AZD6750, rilvegostomig Feasibility Study on the Effect of a Methionine-Reduced Diet on Serum Levels in Pts w/ Solid Tumors NCT07628634EARLY Phase 11 site๐Ÿ“ Orange University of California, Irvine ยท Tests: Methionine-Reduced Diet TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell Cancer NCT06868433Phase 12 sites๐Ÿ“ Atlanta๐Ÿ“ Atlanta Emory University ยท Tests: Autologous Tumor Membrane Vesicles Vaccine, Biospecimen Collection, Computed Tomography, Echocardiography, Magnetic Resโ€ฆ Cosibelimab for CSCC in Patients With Kidney Transplant or Hematologic Malignancy NCT07426484Phase 42 sites๐Ÿ“ Boston๐Ÿ“ Boston Dana-Farber Cancer Institute ยท Tests: Cosibelimab, Prednisone, Sirolimus, Everolimus Clinical Study of CFH Protein Via Ice Microneedles for Radiation-Induced Skin Fibrosis NCT07567235Phase 11 site๐Ÿ“ Chengdu West China Hospital ยท Tests: CFH Protein-loaded Ice Microneedles (0.5 mg), CFH Protein-loaded Ice Microneedles (1.0 mg), CFH Protein-loaded Ice Micrโ€ฆ A Study of GV20-0251 Monotherapy and GV20-0251 in Combination With Pembrolizumab in Participants With Solid Tumor Malignancies NCT05669430Phase 1, Phase 213 sites๐Ÿ“ Los Angeles๐Ÿ“ Denver๐Ÿ“ New Haven GV20 Therapeutics ยท Tests: GV20-0251, GV20-0251, GV20-0251 and Pembrolizumab [KEYTRUDAยฎ], GV20-0251 and Pembrolizumab [KEYTRUDAยฎ] Treatment With Amivantamab and Hyaluronidase or Cetuximab for Advanced Skin Cancer in People With a Weakened Immune System NCT07042295Phase 255 sites๐Ÿ“ Birmingham๐Ÿ“ Gilbert๐Ÿ“ La Jolla National Cancer Institute (NCI) ยท Tests: Amivantamab and Recombinant Human Hyaluronidase, Biospecimen Collection, Cetuximab, Computed Tomography, Magnetic Resonโ€ฆ SUV PDL1/PD1 in Sun Damaged & Sun Protected Human Skin of Participants NCT06177106NA1 site๐Ÿ“ Tucson University of Arizona ยท Tests: Solar Simulated Light Skin Cancer and Hyperthermia and Radiotherapy NCT06384053NA4 sites๐Ÿ“ Aarau๐Ÿ“ Winterthur๐Ÿ“ Bern Kantonsspital Winterthur KSW ยท Tests: Water-filtered infrared-A-hyperthermia (wIRA) hyperthermia combined, Radiotherapy (RT) TIL Therapy in cSCC and MCC NCT07288073Phase 21 site๐Ÿ“ Boston Karam Khaddour, MD, MS ยท Tests: LN-145, Cyclophosphamide, Fludarabine, Interleukin-2 Machine Learning Analysis of Two-photon Fluorescence Microscopy of Dermatologic Biopsies NCT07682831NA1 site๐Ÿ“ Victor University of Rochester ยท Tests: Two photon microscopy imaging PET-imaging of Two Vartumabs in Patients With Solid Tumors NCT06645808EARLY Phase 11 site๐Ÿ“ Groningen Var2 Pharmaceuticals ยท Tests: 89Zr-DFO-N-Suc-F8scFv, 89Zr-DFO-N-Suc-C9scFv, PET/CT scan A First-in-Human Study to Evaluate the Safety, Pharmacokinetics and Pharmacodynamics of KUP-101A in Patients With Selected Advanced Solid Tumors NCT07600476Phase 13 sites๐Ÿ“ Munich๐Ÿ“ Wรผrzburg๐Ÿ“ Mรผnster Kupando GmbH ยท Tests: KUP-101A A Study of DB-1310 in Advanced/Metastatic Solid Tumors NCT05785741Phase 1, Phase 224 sites๐Ÿ“ Sacramento๐Ÿ“ Santa Monica๐Ÿ“ Coral Gables DualityBio Inc. ยท Tests: DB-1310, Trastuzumab, Osimertinib, capecitabine Alpha Radiation Emitters Device (DaRT) in Combination With Check Point Inhibitor for the Treatment of Recurrent Unresectable or mHNSCC NCT05047094NA3 sites๐Ÿ“ Jerusalem๐Ÿ“ Ramat Gan๐Ÿ“ Tel Aviv Alpha Tau Medical LTD. ยท Tests: Diffusing Alpha Radiation Emitters Therapy (DaRT), Pembrolizumab L19IL2/L19TNF in Patients With Cutaneous Squamous Cell Carcinoma NCT07228442Phase 219 sites๐Ÿ“ Orange๐Ÿ“ Atlanta๐Ÿ“ Boston Philogen S.p.A. ยท Tests: L19IL2/L19TNF A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression NCT06682793Phase 1, Phase 210 sites๐Ÿ“ Gilbert๐Ÿ“ La Jolla๐Ÿ“ Los Angeles A2 Biotherapeutics Inc. ยท Tests: A2B395, xT CDx with HLA-LOH assay MEM-288 Oncolytic Virus Alone and in Combination With Standard of Care Therapy in Advanced Solid Tumors NCT05076760Phase 12 sites๐Ÿ“ Tampa๐Ÿ“ Durham Memgen, Inc. ยท Tests: MEM-288 Intratumoral Injection, Nivolumab, Docetaxel (89Zr Panitumumab) With PET/CT for Diagnosing Metastases in Patients With Head and Neck Squamous Cell Carcinoma NCT05747625Phase 11 site๐Ÿ“ Nashville Eben Rosenthal ยท Tests: Panitumumab, Zirconium Zr 89 Panitumumab, Positron Emission Tomography, Computed Tomography, Electronic Health Record Rโ€ฆ Neoadjuvant Nivolumab and Relatlimab in Cutaneous Squamous Cell Carcinoma NCT06288191Phase 21 site๐Ÿ“ Wollstonecraft Melanoma Institute Australia ยท Tests: Nivolumab 240 mg / Relatlimab 80 mg in a fixed dose combination A Study of SH009 Injection in Patients With Advanced Solid Tumors. NCT07390838Phase 11 site๐Ÿ“ Shanghai Nanjing Sanhome Pharmaceutical, Co., Ltd. ยท Tests: SH009 Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program NCT06265285Phase 21 site๐Ÿ“ Jacksonville Mayo Clinic ยท Tests: Home Health Encounter, Nivolumab, Patient Monitoring, Questionnaire Administration Immunotherapy in Combination With Prednisone and Sirolimus for Kidney Transplant Recipients With Unresectable or Metastatic Skin Cancer NCT05896839Phase 1, Phase 226 sites๐Ÿ“ La Jolla๐Ÿ“ Los Angeles๐Ÿ“ Los Angeles National Cancer Institute (NCI) ยท Tests: Biopsy Procedure, Biospecimen Collection, Computed Tomography, Ipilimumab, Kidney Biopsy Microneedle Array Plus Doxorubicin in Cutaneous Squamous Cell Cancer (cSCC) NCT05377905Phase 1, Phase 21 site๐Ÿ“ Pittsburgh Falo, Louis, MD ยท Tests: Microneedle Array Doxorubicin (MNA-D)
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