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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Stage II Rectal Cancer

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC NCT06553885Phase 21 site📍 Tampa H. Lee Moffitt Cancer Center and Research Institute · Tests: Enfortumab Vedotin Hypofractionated Radiotherapy Plus Immunotherapy Versus Conventional Radiotherapy in Locally Recurrent Rectal Cancer NCT06928584Phase 21 site📍 Shanghai Fudan University · Tests: Conventional Radiotherapy, Capecitabine, 5-fluorouracil, folinic acid, Oxaliplatin A Study of Tucatinib and Trastuzumab in People With Rectal Cancer NCT05672524Phase 27 sites📍 Basking Ridge📍 Middletown📍 Montvale Memorial Sloan Kettering Cancer Center · Tests: Trastuzumab, Tucatinib Sacituzumab Govitecan in Metastatic Colorectal Cancer NCT06243393Phase 2, Phase 31 site📍 Heidelberg University Hospital Heidelberg · Tests: Sacituzumab Govitecan (SG), Physicians Choice (PhC). Neoadjuvant Therapy With Tislelizumab for dMMR/MSI-H Stage II-III Colorectal Cancer NCT07352280n/a1 site📍 Beijing Cancer Institute and Hospital, Chinese Academy of Medical S… Neoadjuvant Botensilimab and Balstilimab for the Treatment of Advanced Resectable Colorectal Cancer NEST3 NCT07595874Phase 211 sites📍 Goodyear📍 Corona📍 Duarte City of Hope Medical Center · Tests: Balstilimab, Biospecimen Collection, Botensilimab, Computed Tomography, Magnetic Resonance Imaging Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer. NCT06940388Phase 22 sites📍 Mainz📍 Petah Tikva brenner baruch · Tests: Tislelizumab, Total neoadjuvant therapy (TNT) MR-guided Adaptive Radiotherapy Combined With PD-1 Antibody and CAPOX for Locally Advanced Rectal Cancer NCT06840665Phase 21 site📍 Shanghai Fudan University · Tests: PD-1 antibody, Oxaliplatin, Capecitabine Efficacy and Safety of Trastuzumab Biosimilars and Pertuzumab Biosimilars Combined With Chemotherapy for Neoadjuvant Treatment of Patients With Locally Advanced HER2-positive Rectal Cancer NCT07108127Phase 21 site📍 Beijing Peking Union Medical College Hospital · Tests: Trastuzumab biosimilars and pertuzumab biosimilars plus XELOX Radiation Therapy for the Treatment of Metastatic Gastrointestinal Cancers NCT04221893NA2 sites📍 San Francisco📍 Walnut Creek University of California, San Francisco · Tests: Radiation Therapy (RT) Standard Second-line Therapy With ONgericimab and TOripalimab in pMMR/MSS Colorectal Cancer: a Single-arm Phase II Trial NCT07106034Phase 21 site📍 Shanghai Shanghai Pudong Hospital · Tests: Ongericimab + Toripalimab + Bevacizumab + FOLFOX, Ongericimab + Toripalimab + Bevacizumab + FOLFIRI Study of JYP0015 in Patients With Advanced Solid Tumors Harboring Specific Mutations in RAS NCT06895031Phase 21 site📍 Beijing Guangzhou JOYO Pharma Co., Ltd · Tests: JYP0015 Treating Locally Advanced Rectal Cancer With TAS-102 Chemotherapy Plus Neoadjuvant Radiotherapy NCT05965531Phase 21 site📍 Guangzhou Sun Yat-sen University · Tests: Trifluridine/Tipiracil, intensity-modulated radiotherapy Acupuncture for Oxaliplatin-induced Peripheral Neuropathy in Gastro-intestinal Cancer Patients NCT05850130NA15 sites📍 Amiens📍 Caen📍 Créteil GERCOR - Multidisciplinary Oncology Cooperative Group · Tests: Acupuncture intervention, No acupuncture Liposomal Irinotecan and Leucovorin/5-fluorouracil Plus Bevacizumab in Metastatic Colorectal Cancer NCT06184698Phase 21 site📍 Shijiazhuang Hebei Medical University Fourth Hospital · Tests: liposomal irinotecan, 5-FU, LV, Bevacizumab Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I) NCT06923345Phase 21 site📍 Guangzhou Sixth Affiliated Hospital, Sun Yat-sen University · Tests: Reduced CTV, Conventional CTV A Study of SI-B003, BL-B01D1+SI-B003 and BL-B01D1+PD-1 Monoclonal Antibody in Patients With Locally Advanced or Metastatic Esophageal Cancer, Gastric Cancer, Colorectal Cancer and Other Gastrointestinal Tumors NCT06008054Phase 21 site📍 Beijing Sichuan Baili Pharmaceutical Co., Ltd. · Tests: SI-B003, BL-B01D1, PD-1 Monoclonal Antibody Short-Course Radiotherapy Followed by Immunotherapy Combined With Chemotherapy for Microsatellite Stable Locally Advanced Rectal Cancer: A Prospective, Randomized, Controlled Phase II Clinical Trial NCT07594925Phase 21 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: Sintilimab, Chemotherapy Drugs, radiotherapy PRE-ISPY Phase I/II Oncology Platform Program NCT05868226Phase 1, Phase 210 sites📍 Birmingham📍 Phoenix📍 Aurora QuantumLeap Healthcare Collaborative · Tests: ALX148, Fam-Trastuzumab Deruxtecan-Nxki, Zanidatamab, Tucatinib, TTX-MC138 Trial Utilizing Metronidazole to Optimize the Microbiome of Rectal Adenocarcinoma Undergoing Neoadjuvant Therapy NCT06569368Phase 21 site📍 Houston M.D. Anderson Cancer Center · Tests: Metronidazole Cabozantinib Plus Durvalumab With or Without Tremelimumab in Patients With Gastroesophageal Cancer and Other Gastrointestinal Malignancies NCT03539822Phase 1, Phase 22 sites📍 Westwood📍 Pittsburgh Anwaar Saeed · Tests: Cabozantinib, Durvalumab, Tremelimumab Preoperative Short-Course Radiation Therapy With PROtons Compared to Photons In High-Risk RECTal Cancer (PRORECT) NCT04525989NA9 sites📍 Stockholm📍 Gävle📍 Gothenburg Alexander Valdman · Tests: Radiation therapy Immunotheray Combined With Simvastatin and Target Therapy and Chemotharepy for Advanced Colorectal Cancer NCT07718490Phase 22 sites📍 Nanjing📍 Nanjing The First Affiliated Hospital with Nanjing Medical Universi… · Tests: Adebrelimab Total Neoadjuvant Therapy in Rectal Cancer NCT06162650Phase 21 site📍 Tainan National Cheng-Kung University Hospital · Tests: Short-course radiotherapy, mFOLFOX6 Second-line Standard Treatment Sequential TAS-102 and Bevacizumab Combined With Local Treatment in Advanced Colorectal Cancer NCT06856187Phase 21 site📍 Shanghai Fudan University · Tests: TAS-102+bevacizumab+local treatment, Standard chemotherapy A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of INV-8989 in Patients With Advanced Solid Tumors Harboring KRAS G12D Mutations NCT07610798Phase 1, Phase 21 site📍 Guangzhou Shenzhen Ionova Life Sciences Co., Ltd. · Tests: INV-8989 The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors NCT04624555n/a1 site📍 Cleveland Case Comprehensive Cancer Center HDR Endorectal Brachytherapy With 3D-Printed Guidance and Local Shielding for Rectal Cancer Organ Preservation NCT07786493NA1 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: High-Dose-Rate Endorectal Brachytherapy ctDNA Monitoring to Predict the Efficacy of TNT for Rectal Cancer NCT06589388n/a1 site📍 Ho Chi Minh City Gene Solutions GM103 Intratumoral Injection in Patients With Locally Advanced, Unresectable, Refractory and/or Metastatic Solid Tumors NCT06265025Phase 1, Phase 24 sites📍 Goyang-si📍 Seoul📍 Seoul GeneMedicine Co., Ltd. · Tests: GM103 (Part A), GM103 (Part B), GM103 and Pembrolizumab (Part C)
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