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Trial Match

Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for TCR-T Cells

Characterization of T-cell Repertoire in Patients With Acute Myeloid Leukemia Undergoing Donor Stem Cell Transplant NCT03921047n/a1 site๐Ÿ“ Los Angeles University of Southern California ยท Tests: Biospecimen Collection, Laboratory Biomarker Analysis NY-ESO-1 TCR-T Cells for NY-ESO-1 Positive Subjects With Advanced Solid Tumors NCT05881525Phase 11 site๐Ÿ“ Chongqing TCRCure Biopharma Ltd. ยท Tests: TC-N201 cells, IL-2, Fludarabine, Cyclophosphamide, Nab-paclitaxel Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors NCT02508038Phase 11 site๐Ÿ“ Madison University of Wisconsin, Madison ยท Tests: TCRฮฑฮฒ+/CD19+ depleted Haploidentical HSCT, Zoledronate T Cell Receptor Immunotherapy for Patients With Metastatic Non-Small Cell Lung Cancer NCT02133196Phase 21 site๐Ÿ“ Bethesda National Cancer Institute (NCI) ยท Tests: Aldesleukin, Fludarabine, Cyclophosphamide, Young TIL A Long Term Follow-up Study of TScan TCR-T Products NCT06976736n/a2 sites๐Ÿ“ Duarte๐Ÿ“ New York TScan Therapeutics, Inc. ยท Tests: Observational Tebentafusp Regimen Versus Investigator's Choice in Previously Treated Advanced Melanoma (TEBE-AM) NCT05549297Phase 382 sites๐Ÿ“ Phoenix๐Ÿ“ Jacksonville๐Ÿ“ Orlando Immunocore Ltd ยท Tests: Tebentafusp, Tebentafusp with Pembrolizumab, Investigators Choice TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Primary Immunodeficiency and Inherited Metabolic Disorders in Children NCT04414046Phase 21 site๐Ÿ“ St. Petersburg Johns Hopkins All Children's Hospital ยท Tests: Haploidentical Hematopoietic Cell Transplantation An Open-label, Phase I Clinical Trial of Super1 TCR-T in NY-ESO-1-positive Patients With Advanced Solid Tumors NCT06942143Phase 11 site๐Ÿ“ Guangzhou Guangzhou FineImmune Biotechnology Co., LTD. ยท Tests: Super1 TCR-T A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies. NCT06542250Phase 1, Phase 231 sites๐Ÿ“ La Jolla๐Ÿ“ Boston๐Ÿ“ Rochester AstraZeneca ยท Tests: AZD5492 KSX01-TCRT Injection Project in Solid Tumors NCT05811975EARLY Phase 11 site๐Ÿ“ Nanning TCRx Therapeutics Co.Ltd ยท Tests: KSX01-TCRT injection TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-ALL NCT06481735Phase 1, Phase 26 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Chinese PLA General Hospital ยท Tests: TCR reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T cell, Fludarabine, Cyclophosphamide TCR1188-ABC Cells in KRAS-mutated Cancers NCT07594067Phase 11 site๐Ÿ“ Philadelphia University of Pennsylvania ยท Tests: TCR1188-ABC cells, Fludarabine + Cyclophosphamide combination, Tocilizumab Phase 1 Study to Investigate TCRTs KRAS Mutation in Unresectable, Advanced, and/or Metastatic Solid Tumors NCT06218914Phase 118 sites๐Ÿ“ Duarte๐Ÿ“ Los Angeles๐Ÿ“ Newport Beach AstraZeneca ยท Tests: NT-112: Autologous, engineered T Cells targeting KRAS G12D, AZD0240: Autologous, engineered T Cells targeting KRAS G12D Mutant KRAS G12V-specific TCR Transduced T Cell Therapy for Advanced Pancreatic Cancer NCT04146298Phase 1, Phase 21 site๐Ÿ“ Shanghai Changhai Hospital ยท Tests: Cyclophosphamide, Fludarabine, Mutant KRAS G12V-specific TCR transduced autologous T cells, Anti-PD-1 monoclonal antiboโ€ฆ MAGE-A4-directed TCR-T in the Treatment Amongst Subjects With Advanced Solid Tumors NCT06170294Phase 11 site๐Ÿ“ Beijing Peking University ยท Tests: TCR-MAGE-A4 T-Cells TCR-engineered T Cells (NW-101C) in Patients With Solid Malignant Tumors NCT07266298Phase 11 site๐Ÿ“ Beijing Neowise Biotechnology ยท Tests: NW-101C FORTRAS: A Study of MSK-TCR5 in People With Solid Tumor Cancers NCT07638371Phase 17 sites๐Ÿ“ Basking Ridge๐Ÿ“ Middletown๐Ÿ“ Montvale Memorial Sloan Kettering Cancer Center ยท Tests: MSK-TCR5 Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC NCT07145450Phase 1, Phase 210 sites๐Ÿ“ Copenhagen๐Ÿ“ Berlin๐Ÿ“ Dresden Anocca AB ยท Tests: ANOC-001 (TCR-T cells targeting KRAS G12V mutation presented by specific HLA alleles), ANOC-002 (TCR-T cells targeting โ€ฆ TCR-T Cell Immunotherapy of Lung Cancer and Other Solid Tumors NCT03778814Phase 11 site๐Ÿ“ Guanzhou Second Affiliated Hospital of Guangzhou Medical University ยท Tests: TCR-T cells Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Young Adults NCT04249830NA1 site๐Ÿ“ Palo Alto Alice Bertaina ยท Tests: Allogeneic Stem Cell Transplant, CliniMACS TCR ฮฑ/ฮฒ Reagent Kit and CliniMACS CD19 MT2021-08T Cell Receptor Alpha/Beta Depletion PBSC Transplantation for Heme Malignancies NCT05735717Phase 21 site๐Ÿ“ Minneapolis Masonic Cancer Center, University of Minnesota ยท Tests: Fludarabine, Busulfan, Melphalan, Rituximab, Levetiracetam E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated Cancers NCT05686226Phase 23 sites๐Ÿ“ Bethesda๐Ÿ“ New Brunswick๐Ÿ“ New Brunswick Christian Hinrichs ยท Tests: E7 TCR-T cells, Aldesleukin TCR Reserved and Power3 (SPPL3) Gene Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B Cell Lymphoma NCT06323525Phase 1, Phase 23 sites๐Ÿ“ Beijing๐Ÿ“ Beijing๐Ÿ“ Beijing Chinese PLA General Hospital ยท Tests: TCR reserved and Power3 (SPPL3) gene knock-out allogeneic CD19-targeting CAR-T cell (ATHENA-2 CAR-T), Fludarabine, Cyclโ€ฆ T Cell Receptor Gene-Engineered T Cell Therapy Targeting KRAS Mutations in the Treatment of Subjects With Advanced Solid Tumor NCT06484790Phase 11 site๐Ÿ“ Tianjin Ting Deng ยท Tests: NW-301V, NW-301D Stem Cell Transplant From Donors After Alpha Beta Cell Depletion in Children and Adults With T-allo10 Cells Addback NCT04640987Phase 11 site๐Ÿ“ Palo Alto Porteus, Matthew, MD ยท Tests: Allogeneic Stem Cell Transplant, CliniMACS Prodigy System, T-allo10 cells addback Study of Autoimmune Lymphoproliferative Syndrome (ALPS) NCT00001350n/a1 site๐Ÿ“ Bethesda National Institute of Allergy and Infectious Diseases (NIAIโ€ฆ Phase I/Ib Study of NK Expressing an Affinity-enhanced T-cell Receptor (TCR) Against the NY-ESO-1 NCT06083883Phase 11 site๐Ÿ“ Houston M.D. Anderson Cancer Center ยท Tests: Fludarabine phosphate, NY-ESO-1 TCR/IL-15 NK, Cyclophosphamide NY-ESO-1-redirected T Cells in Patients With Advanced Melanoma and Sarcoma NCT06889766Phase 12 sites๐Ÿ“ Lausanne๐Ÿ“ Lausanne Centre Hospitalier Universitaire Vaudois ยท Tests: NY-ESO-1 TCR redirected autologous T cell product, Low-dose irradiation, Non-myeloablative lymphodepleting chemotherapy Autologous HBV-TCR T Cell Therapy (LioCyx-M) for the Treatment of Hepatocellular Carcinoma NCT06961617Phase 11 site๐Ÿ“ Beijing Lion TCR Pte. Ltd. ยท Tests: LioCyx-M, HBV antigen-specific TCR-redirected T cells TCR Alpha Beta T-cell Depleted Haploidentical HCT in the Treatment of Non-Malignant Hematological Disorders in Children NCT04356469Phase 21 site๐Ÿ“ St. Petersburg Johns Hopkins All Children's Hospital ยท Tests: Haploidentical Hematopoietic Cell Transplantation
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