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Clinical trials test new treatments โ€” sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Thyroid-Associated Ophthalmopathy

Open-Label Extension Study of MHB018A in Subjects With Thyroid Eye Disease NCT07262476Phase 31 site๐Ÿ“ Shanghai Minghui Pharmaceutical (Hangzhou) Ltd ยท Tests: MHB018A injection Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford NCT01793168n/a1 site๐Ÿ“ Sioux Falls Sanford Health Establishment of Multiparametric Prediction Models for Moderate to SevereThyroid Associated Ophthalmopathy NCT06590220n/a1 site๐Ÿ“ Shanghai Shanghai Changzheng Hospital Systemic Inflammation, Thyroid Autoimmunity and Neuroretinal Changes in Graves Disease NCT07480720n/a1 site๐Ÿ“ ElรขzฤฑฤŸ Elazฤฑg Fethi Sekin Sehir Hastanesi Validating Immunological Markers Associated With Mental Fatigue in Graves' Disease NCT06081439n/a1 site๐Ÿ“ Gothenburg Vastra Gotaland Region Tofacitinib for Glucocorticoid-Resistant Moderate-to-Severe Thyroid Eye Disease NCT07547930Phase 21 site๐Ÿ“ Xiamen The First Affiliated Hospital of Xiamen University ยท Tests: Tofacitinib Bimatoprost as a Treatment for Graves' Orbitopathy NCT03708627EARLY Phase 11 site๐Ÿ“ Seattle Johns Hopkins University ยท Tests: Bimatoprost Ophthalmic Evaluation of ETHY-001 for Safety, Tolerability, and Clinical Activity in Thyroid Eye Disease NCT07885605Phase 13 sites๐Ÿ“ Orland Park๐Ÿ“ Las Vegas๐Ÿ“ Wilmington Ethyreal Bio, Inc. ยท Tests: ETHY-001, Placebo Statin and Vitamin D Treatment in Patients With Thyroid Eye Disease NCT07400757NA1 site๐Ÿ“ Taipei Taipei Veterans General Hospital, Taiwan ยท Tests: Atorvastatin (Lipitor), Vitamin D Efficacy and Safety of Sequential Hormone Therapy and Tetuzumab Therapy in Patients With Moderate to Severe TAO in the Active Stage After Glucocorticoid Treatment. NCT07152366Phase 41 site๐Ÿ“ Shanghai Shanghai Changzheng Hospital ยท Tests: IBI311, Glucocorticoids A Study of Teprotumumab N01 in Subjects With Active Thyroid Eye Disease NCT07265258Phase 41 site๐Ÿ“ Shanghai Innovent Biologics (Suzhou) Co. Ltd. ยท Tests: Teprotumumab N01, Methylprednisolone Describe the Progression of Inflammatory Orbitopathy and the Biological Progression of Patients Receiving Second-line Treatment NCT07117981n/a9 sites๐Ÿ“ Paris๐Ÿ“ Caen๐Ÿ“ Lyon Centre Hospitalier National d'Ophtalmologie des Quinze-Vingโ€ฆ Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease NCT04936854Phase 21 site๐Ÿ“ Bergen Haukeland University Hospital ยท Tests: Sirolimus 1 mg Oral Tablet, Methylprednisolone A Clinical Study to Evaluate the Efficacy and Safety of IBI311 in Subjects With Inactive Thyroid Eye Disease NCT07113262Phase 31 site๐Ÿ“ Shenyang Innovent Biologics (Suzhou) Co. Ltd. ยท Tests: IBI311, Placebo The Safety and Efficacy of Sequential Hormone Therapy and IBI311 Therapy in Patients With Active Moderate to Severe TAO in the Initial Treatment. NCT07152340Phase 42 sites๐Ÿ“ Changhua๐Ÿ“ Shanghai Shanghai Changzheng Hospital ยท Tests: IBI311, Glucocorticoids Treatment of Chronic Thyroid Eye Disease With MHB018A NCT07622121Phase 31 site๐Ÿ“ Coral Gables Minghui Pharmaceutical (Hangzhou) Ltd ยท Tests: MHB018A injection, MHB018A injection Placebo An Open-label, Rollover Trial to Evaluate the Efficacy and Safety of AMG 732 in Participants With Thyroid Eye Disease NCT07438405Phase 28 sites๐Ÿ“ Little Rock๐Ÿ“ Kissimmee๐Ÿ“ Orland Park Amgen ยท Tests: AMG 732 Early Risk Stratification of Thyroid Eye Disease in Newly Diagnosed Graves' Disease NCT07812194n/a1 site๐Ÿ“ Herlev University of Copenhagen ยท Tests: Study-related ophthalmological assessment and biospecimen collection, Blood biomarkers and standardized blood samples iโ€ฆ Orbital Radiotherapy in Grave's Ophthalmopathy 1 Week vs 2 Weeks (OraGO-1 Trial) NCT06392906Phase 31 site๐Ÿ“ Bangkok Noi Janjira Petsuksiri ยท Tests: Short course radiation therapy, Standard course radiation therapy A Study of IBI3031 in Participants With Thyroid Eye Disease NCT07622368Phase 11 site๐Ÿ“ Shenyang Innovent Biologics (Suzhou) Co. Ltd. ยท Tests: IBI3031, placebo Treatment of Gravesยดophthalmopathy with Simvastatin (GO-S) NCT03131726Phase 31 site๐Ÿ“ Malmรถ Lund University ยท Tests: Simvastatin 40mg Comparative Evaluation of 68Ga-FAPI and 68Ga-DOTATATE PET/CT and PET/MRI in Thyroid Eye Disease NCT07835607n/a1 site๐Ÿ“ Chongqing Daping Hospital and the Research Institute of Surgery of thโ€ฆ ยท Tests: 68Ga-FAPI PET/CT and PET/MR Imaging, 68Ga-DOTATATE PET/CT and PET/MR Imaging A Clinical Study of Cizutamig in Thyroid Eye Disease NCT07597200Phase 114 sites๐Ÿ“ Hefei๐Ÿ“ Beijing๐Ÿ“ Fuzhou Candid Therapeutics ยท Tests: Cizutamig will be dosed according to the protocol. Evaluation of High Dose Prednisolone Pharmacokinetics in the Acute and Chronic Setting NCT05012033n/a1 site๐Ÿ“ London Imperial College London ยท Tests: No intervention - prednisolone is taken as part if routine clinical care. Study to Assess Linsitinib in Participants With Moderate to Severe Active Thyroid Eye Disease (TED) NCT07753603Phase 318 sites๐Ÿ“ Glendale๐Ÿ“ Beverly Hills๐Ÿ“ Canoga Park Sling Therapeutics, Inc. ยท Tests: linsitinib, Placebo Extension Study of Two Doses of Linsitinib in Subjects With Active, Moderate to Severe Thyroid Eye Disease (TED) NCT06112340Phase 2, Phase 32 sites๐Ÿ“ Miami๐Ÿ“ Morgantown Sling Therapeutics, Inc. ยท Tests: linsitinib Hydroxychloroquine in Mild Graves' Orbitopathy NCT05126147Phase 42 sites๐Ÿ“ Hsinchu๐Ÿ“ Taipei National Taiwan University Hospital ยท Tests: Hydroxychloroquine Screening, Classification, and Outcome Prediction Ensemble Using Orbital MRI for Thyroid Eye Disease: The TED SCOPE National Multicenter Registry Study NCT07716397n/a1 site๐Ÿ“ Shanghai Shanghai Changzheng Hospital ยท Tests: MRI scan๏ผŒocular ultrasound Evaluating the Efficacy and Safety of Teprotumumab N01 in Patients With Thyroid Eye Disease. NCT07423013NA1 site๐Ÿ“ Beijing Peking University Third Hospital ยท Tests: [18F]AlF-NOTA-FAPI-04PET/CT, 5.0-T high-resolution MRI Exploring the Value of 18F-AlF-FAPI PET/CT in Assessing the Activity of Thyroid Eye Disease NCT06359795NA1 site๐Ÿ“ Beijing Peking University Third Hospital ยท Tests: 18F-AlF-FAPI PET/CT, 99mTc-DTPA SPECT/CT
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