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Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Total Knee Arthroplasty (Postoperative Pain)

Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients NCT07271849Phase 41 site📍 Jinan Qianfoshan Hospital · Tests: Nalbuphine Hydrochloride injection was administered during anesthesia induction., Nalbuphine Hydrochloride injection wa… Fiber Smoothie Supplement NCT06896240NA1 site📍 New York Hospital for Special Surgery, New York · Tests: Assigned Interventions Binaural Beats for Postoperative Pain and Anxiety Reduction NCT07437469NA1 site📍 Miami University of Miami · Tests: Binaural Beats Audio Intervention, Music of Choice Regional Anesthesia in TKA: Impact on Postoperative Joint Motion and Patient Satisfaction NCT07124494NA1 site📍 Konya Konya City Hospital · Tests: Regional anethesia A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation NCT04432012Phase 41 site📍 Lugano Christian Candrian · Tests: Dexamethasone Sodium Phosphate 4 mg/ml intravenous, Dexamethasone Sodium Phosphate 4 mg/ml intra-articular Tranexamic Acid Use on Pain, Mobility and Bleeding Following Total Hip and Total Knee Arthroplasty NCT06208267NA1 site📍 Montreal St. Mary's Research Center, Canada · Tests: Tranexamic acid Supplementary Nerve Blocks Added to the Adductor Canal Block for Postoperative Pain Management in Primary Total Knee Arthroplasty: A Randomized Controlled Comparison of Sciatic, BiFeS, and IPACK Techniques NCT07242170NA1 site📍 Erzincan Erzincan University · Tests: Adductor canal block, BiFeS Block (Biceps Femoris Short Head Block), IPACK block, Sciatic Nerve Block Effect of Foam Rolling After Total Knee Arthroplasty NCT07848126NA1 site📍 Izmir Dokuz Eylul University · Tests: Foam rolling after total knee arthroplasty, Standard home exercise program after total knee arthroplasty Methadone in TKA for Post-op Pain and Opioid Reduction NCT07226076Phase 31 site📍 Charleston Medical University of South Carolina · Tests: Methadone Hydrochloride Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty NCT06083480Phase 41 site📍 Nashville Vanderbilt University Medical Center · Tests: GlyNAC (combination of glycine and n-acetylcysteine), Placebo Continuous Versus Single Injection Adductor Canal Blocks for Outpatient Total Knee Arthroplasty NCT06784882Phase 41 site📍 La Jolla University of California, San Diego · Tests: continuous peripheral nerve block with OnQ pump, single injection nerve block Ultrasonographic Predictors of Adductor Canal Block Effectiveness in Total Knee Arthroplasty NCT07730216n/a1 site📍 Konya Konya City Hospital · Tests: Adductor Canal Block (ACB) Only The Effect of Distal Versus Proximal iPACK on Pain After Total Knee Arthroplasty NCT07080892NA1 site📍 Bratislava Comenius University · Tests: distal iPACK, proximal iPACK Local Infiltration Analgesia Versus Quadruple Nerve Blocks in Total Knee Arthroplasty. NCT07477730NA1 site📍 Toulouse CMC Ambroise Paré · Tests: Surgical local infiltration, Obturator nerve block, Femoral nerve block, Sciatic nerve block, Lateral femoral cutaneous… REIKI IN TOTAL KNEE ARTHROPLASTY PATIENTS (REIKI TKA ) NCT07442435NA1 site📍 Sinop Ondokuz Mayıs University · Tests: Reiki Therapy Enhanced Recovery After Surgery (ERAS) Total Knee Replacement (TKR) With a Transitional Pain Service NCT03747146NA1 site📍 New York Hospital for Special Surgery, New York · Tests: Continuous Adductor Canal Catheter (ACC), Adductor Canal block with sham catheter Persistent Post Surgical Pain After Total Knee Arthroplasty NCT06182059NA1 site📍 Monza Policlinico di Monza SpA · Tests: continuous peripheral nerve block Post-Operative Pain Relief: Zynrelef or Periarticular Injections in RATKA NCT07430085Phase 41 site📍 Cranberry Township Allegheny Singer Research Institute (also known as Alleghen… · Tests: bupivacaine-meloxicam (extended release), Bupivacaine, Ketorolac, Lidocaine (drug) BiFeS vs. iPACK in Postoperative Knee Arthroplasty Analgesia NCT07360392NA1 site📍 Amasya Amasya University · Tests: Biceps Femoris Short Head Block (BiFeS), Infiltration Between The Popliteal Artery and The Capsule of The Knee, Adducto… Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE) NCT06423716Phase 42 sites📍 Toronto📍 Toronto Sunnybrook Health Sciences Centre · Tests: Duloxetine, Placebo ACU_Knee: Role of Acupuncture in Knee Prosthetic Surgery NCT07123805NA1 site📍 Pavia Fondazione IRCCS Policlinico San Matteo di Pavia · Tests: Acupuncture group Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN NCT07548385Phase 31 site📍 New York Icahn School of Medicine at Mount Sinai · Tests: Suzetrigine, Placebo Effects of Different Relaxation Therapies on Pain and Sleep in Hip and Knee Arthroplasty Patients NCT07354542NA1 site📍 Bartın Bartın Unıversity · Tests: Virtual Reality-Based Relaxation, Traditional Relaxation Therapy Post-op Prednisone and Glucose Monitoring in TKA NCT07630896Phase 41 site📍 New York Columbia University · Tests: Prednisone, Continuous Glucose Monitor, InkWell Health Tattoos REST-Knee: A Pilot RCT of 72-Hour Knee Immobilization and Pain Outcomes NCT07511842NA1 site📍 Sherbrooke Université de Sherbrooke · Tests: Knee Extension Brace (Zimmer-type), Early Mobilization (Standard Care) Radiofrequency Ablation for the Treatment of Post-knee Arthroplasty Chronic Pain. NCT05920382NA1 site📍 Barcelona Consorci Sanitari de l'Alt Penedès i Garraf · Tests: Radiofrequency ablation of peripheral nerves. Comparing ACB+IPACK and ACB+BiFeS Block Combinations for Analgesia in Total Knee Arthroplasty NCT07561333NA1 site📍 Çorum Hitit University · Tests: ACB+IPACK Group, ACB+BiFeS Group Medrol Dosepak for Outpatient Total Knee Arthroplasty NCT05097976Phase 41 site📍 Oak Brook Rush University Medical Center · Tests: Methylprednisolone, Placebo Feasibility of Breathwork Intervention With Older Adults After Knee Surgery NCT07464860NA1 site📍 Tucson University of Arizona · Tests: A 5-minute Asynchronous Breathwork Intervention, A 5-minute Asynchronous Card Game Video Promoting Sleep to Alleviate Pain - Arthroplasty NCT06145516NA1 site📍 Uppsala Uppsala University · Tests: Cognitive behavioral therapy for insomnia (CBT-I), Sleep education therapy (SET)
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