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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Treatment Resistant Depression

Dutch-Depression Outcome Trial Comparing 5 Day Multi Daily Neuronavigated Theta Burst Sessions With 6 Weeks rTMS NCT05900271NA4 sites📍 Nijmegen📍 Amsterdam📍 Amsterdam-Zuidoost Amsterdam UMC, location VUmc · Tests: rTMS, iTBS An Open-Label Study to Evaluate the Safety, Tolerability and Pharmacodynamics of BPL-003 in Patients With Treatment Resistant Depression NCT05660642Phase 23 sites📍 Liverpool📍 London📍 London Beckley Psytech Limited · Tests: BPL-003 Esketamine Nasal Spray in Real-World Settings in Treatment-Resistant Depression NCT07146503n/a5 sites📍 Genova📍 Genova📍 Chieti Riccardo Guglielmo · Tests: Esketamine (Intranasal Spray) Schema Therapy for Patients With Chronic Treatment Resistant Depression NCT05833087NA6 sites📍 Ballerup Municipality📍 Copenhagen📍 Copenhagen Region of Southern Denmark · Tests: Schema therapy, Other psychotherapy, Standard care package content Closed-Loop Deep Brain Stimulation for Major Depression NCT04004169NA1 site📍 San Francisco Andrew Krystal · Tests: Stimulation-ON, Stimulation-OFF, Stimulation-ON Active Control One-Day cTBS Over the Precuneus NCT07758010NA1 site📍 Belmont Mclean Hospital · Tests: Precuneus-targeted continuous theta-burst stimulation, Left dorsolateral prefrontal cortex intermittent theta-burst sti… Coaching as an Adjunct to Ketamine Therapy for Treatment-Resistant Depression NCT07563868NA2 sites📍 Boston📍 Boston Massachusetts General Hospital · Tests: Psychedelic Integration Coaching RESISTance Exercise for Depression Trial NCT06110897NA2 sites📍 Ames📍 Madison University of Wisconsin, Madison · Tests: High Dose Resistance Exercise Training, Low Dose Resistance Exercise Training Group Relationship of Peripheral Inflammatory and Neuroprotective Biomarkers With Response to Intermittent Theta Burst Stimulation in Treatment-Resistant Depression NCT07673913NA2 sites📍 Ankara📍 Ankara Gulhane Training and Research Hospital · Tests: Intermittent Theta Burst Stimulation (iTBS) Transcranial Ultrasonic Stimulation in Treatment-resistant Depression : an Open-label Pilot Trial NCT06085950NA1 site📍 Paris Centre Hospitalier St Anne · Tests: Transcranial Ultrasonic Stimulation prototype SAINT® Therapy for Memory Problems in Older Adults With Treatment-Resistant Depression NCT07876908NA1 site📍 Costa Mesa BrainHealth Solutions, Inc. · Tests: Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT®) with the Magnus Neuromodulation System Biomarker-guided rTMS for Treatment Resistant Depression NCT04041479Phase 32 sites📍 Stanford📍 New York Weill Medical College of Cornell University · Tests: Repetitive Transcranial Magnetic Stimulation, Repetitive Transcranial Magnetic Stimulation A Study to Assess Effectiveness and Efficiency of VNS Therapy in Patients With Difficult to Treat Depression. NCT03320304n/a18 sites📍 Vienna📍 Leuven📍 Bamberg LivaNova · Tests: Vagal Nerve Simulation (VNS) Therapy A Randomized, Double-Blind Controlled Comparison of NRX-101 vs. Placebo for Adults Being Treated With Robotic Transcranial Magnetic Stimulation for Treatment Resistant Depression: The SPARC-TMS Trial NCT07227103Phase 2, Phase 33 sites📍 Sarasota📍 West Palm Beach📍 Belmont NeuroRx, Inc. · Tests: Neuronavigated robotic-enabled TMS, NRX-101, Sham TMS, Oral Placebo Mindfulness Engaged Neurostimulation for Depression (MEND II) NCT07512284Phase 21 site📍 San Diego University of California, San Diego · Tests: Medi-TBS Maintenance rTMS for Depression (Maitr-De) NCT06938841NA3 sites📍 San Diego📍 New York📍 Canberra University of California, San Diego · Tests: Transcranial Magnetic Stimulation (TMS) - Standard maintenance rTMS:, Transcranial Magnetic Stimulation (TMS) - Cluster… Focused Ultrasound Neuromodulation in Patients With Treatment-Resistant Depression NCT07094789NA1 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: Next Generation Dome Helmet (NGDH) E-field Guided iTBS for Treatment Resistant Depression NCT05583747NA2 sites📍 Toronto📍 Toronto Centre for Addiction and Mental Health · Tests: iTBS qEEG Brain Signature of Depression & Neuromodulation-induced Recovery NCT06719427Phase 12 sites📍 North York📍 Toronto Sunnybrook Health Sciences Centre · Tests: Transcranial Magnetic Stimulation Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant Depression NCT07422519NA1 site📍 Barcelona Hospital Universitari Vall d'Hebron Research Institute · Tests: Virtual-Reality-based mindfulness intervention, Esketamine Treatment as Usual (ESK) rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression NCT06511544NA1 site📍 Indianapolis Indiana University · Tests: Transcranial magnetic stimulation Cannabidiol Oil for Treatment-Resistant Major Depression NCT07696871Phase 1, Phase 21 site📍 Tubarão Universidade do Sul de Santa Catarina · Tests: Full-spectrum CBD oil 100 mg/mL, Placebo oil (MCT oil) Olfactory and Brain Stimulations in Treatment-resistant Depression NCT05661383NA1 site📍 Bron Hôpital le Vinatier · Tests: Non-invasive brain stimulation protocol (intermittent theta burst protocol (iTBS)) combined with pleasant odors deliver… COpenhagen Magnetic Personalized Accelerated Brain Circuit Therapy for Treatment Resistant Depression NCT06895863NA3 sites📍 Glostrup Municipality📍 Hilleroed📍 Hvidovre Danish Research Centre for Magnetic Resonance · Tests: MagVenture XP Orange Stimulator and active side of MagVenture COOL-B65 coil., Device: MagVenture XP Orange Stimulator a… Cortical Inhibition as a Biomarker of Response in a Comparison of Bilateral Versus Unilateral Accelerated Theta Burst Stimulation for Suicidal Ideation in Treatment-Resistant Depression -COMBAT-SI NCT05377177NA1 site📍 San Diego University of California, San Diego · Tests: Accelerated Theta Burst Stimulation Ketamine Alcohol (in Treatment-Resistant Depression) NCT02122562Phase 21 site📍 Iowa City Mark Niciu · Tests: Ketamine TACS on High-inflammatory and Refractory Depression NCT06812923NA1 site📍 Tianjin Tianjin Anding Hospital · Tests: transcranial Alternating Current Stimulation (tACS), Sham stimulation 40 Hz Light Neurostimulation for Patients With Depression (FELIX) NCT05680220NA1 site📍 Copenhagen Klaus Martiny · Tests: Neurostimulation System (NSS): Active Setting, Neurostimulation System (NSS): Sham Setting Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT) NCT07569198Phase 21 site📍 Toronto Joshua Rosenblat · Tests: Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT) Establishing Mobile Transcranial Magnetic Stimulation NCT06748209Phase 41 site📍 Charleston Medical University of South Carolina · Tests: Left prefrontal Transcranial Magnetic Stimulation (TMS), FDA cleared TMS for treating depression
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