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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Treatment Resistant Major Depression

Closed-Loop Deep Brain Stimulation for Major Depression NCT04004169NA1 site📍 San Francisco Andrew Krystal · Tests: Stimulation-ON, Stimulation-OFF, Stimulation-ON Active Control One-Day cTBS Over the Precuneus NCT07758010NA1 site📍 Belmont Mclean Hospital · Tests: Precuneus-targeted continuous theta-burst stimulation, Left dorsolateral prefrontal cortex intermittent theta-burst sti… RESISTance Exercise for Depression Trial NCT06110897NA2 sites📍 Ames📍 Madison University of Wisconsin, Madison · Tests: High Dose Resistance Exercise Training, Low Dose Resistance Exercise Training Group Relationship of Peripheral Inflammatory and Neuroprotective Biomarkers With Response to Intermittent Theta Burst Stimulation in Treatment-Resistant Depression NCT07673913NA2 sites📍 Ankara📍 Ankara Gulhane Training and Research Hospital · Tests: Intermittent Theta Burst Stimulation (iTBS) Biomarker-guided rTMS for Treatment Resistant Depression NCT04041479Phase 32 sites📍 Stanford📍 New York Weill Medical College of Cornell University · Tests: Repetitive Transcranial Magnetic Stimulation, Repetitive Transcranial Magnetic Stimulation Mindfulness Engaged Neurostimulation for Depression (MEND II) NCT07512284Phase 21 site📍 San Diego University of California, San Diego · Tests: Medi-TBS Maintenance rTMS for Depression (Maitr-De) NCT06938841NA3 sites📍 San Diego📍 New York📍 Canberra University of California, San Diego · Tests: Transcranial Magnetic Stimulation (TMS) - Standard maintenance rTMS:, Transcranial Magnetic Stimulation (TMS) - Cluster… E-field Guided iTBS for Treatment Resistant Depression NCT05583747NA2 sites📍 Toronto📍 Toronto Centre for Addiction and Mental Health · Tests: iTBS qEEG Brain Signature of Depression & Neuromodulation-induced Recovery NCT06719427Phase 12 sites📍 North York📍 Toronto Sunnybrook Health Sciences Centre · Tests: Transcranial Magnetic Stimulation Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant Depression NCT07422519NA1 site📍 Barcelona Hospital Universitari Vall d'Hebron Research Institute · Tests: Virtual-Reality-based mindfulness intervention, Esketamine Treatment as Usual (ESK) rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression NCT06511544NA1 site📍 Indianapolis Indiana University · Tests: Transcranial magnetic stimulation Cannabidiol Oil for Treatment-Resistant Major Depression NCT07696871Phase 1, Phase 21 site📍 Tubarão Universidade do Sul de Santa Catarina · Tests: Full-spectrum CBD oil 100 mg/mL, Placebo oil (MCT oil) COpenhagen Magnetic Personalized Accelerated Brain Circuit Therapy for Treatment Resistant Depression NCT06895863NA3 sites📍 Glostrup Municipality📍 Hilleroed📍 Hvidovre Danish Research Centre for Magnetic Resonance · Tests: MagVenture XP Orange Stimulator and active side of MagVenture COOL-B65 coil., Device: MagVenture XP Orange Stimulator a… Ketamine Alcohol (in Treatment-Resistant Depression) NCT02122562Phase 21 site📍 Iowa City Mark Niciu · Tests: Ketamine 40 Hz Light Neurostimulation for Patients With Depression (FELIX) NCT05680220NA1 site📍 Copenhagen Klaus Martiny · Tests: Neurostimulation System (NSS): Active Setting, Neurostimulation System (NSS): Sham Setting Ketamine With Dialectical Behavioural Therapy (DBT) for Suicidality in Individuals With Treatment-Resistant Depression and Borderline Personality Disorder (KET-DBT) NCT07569198Phase 21 site📍 Toronto Joshua Rosenblat · Tests: Ketamine Hydrochloride, Midazolam Hydrochloride, Dialectical Behavioral Therapy (DBT) Establishing Mobile Transcranial Magnetic Stimulation NCT06748209Phase 41 site📍 Charleston Medical University of South Carolina · Tests: Left prefrontal Transcranial Magnetic Stimulation (TMS), FDA cleared TMS for treating depression Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot Study NCT06732089n/a1 site📍 Toronto Unity Health Toronto ACT_for Alcohol Use Disorder and Depression NCT06620276NA1 site📍 Montreal Centre hospitalier de l'Université de Montréal (CHUM) · Tests: Acceptance and Commitment Therapy, Ketamine The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant Depression NCT06163625NA1 site📍 Toronto Unity Health Toronto · Tests: Repetitive Transcranial Magnetic Stimulation, Research Interview, Questionnaires, Brain Scan, Saliva Samples Accelerated TMS for Treatment-Resistant ECT NCT07115628NA1 site📍 Jette Universitair Ziekenhuis Brussel · Tests: Transcranial Magnetic Stimulation Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND) NCT06423430NA26 sites📍 Birmingham📍 Los Angeles📍 Los Angeles Abbott Medical Devices · Tests: Sham-stimulation, Active-stimulation Efficacy of Psilocybin and Trazodone Combination in Treatment-resistant Depression: a Randomized Controlled Proof-of-concept Study (PSILOTRAZ) NCT07210112Phase 21 site📍 Paris Centre Hospitalier St Anne · Tests: Psilocybin 25 mg per os, Trazodone 5mg, Trazodone 30 mg, Placebo of psilocybin, Placebo of trazodone EEG Microstate and Neuroinflammatory Biomarkers in Older Age Patients With Major Depressive Disorder Receiving ECT NCT07740694n/a1 site📍 Istanbul Istanbul University - Cerrahpasa · Tests: Electroconvulsive Therapy Psilocybin rTMS for Treatment Resistant Depression NCT06132178Phase 21 site📍 Austin University of Texas at Austin · Tests: Psilocybin, Accelerated intermittent theta burst (aiTBS) rTMS treatment, Low-dose psilocybin, Sham Accelerated intermit… Interleaved TMS-fMRI in Ultra-treatment Resistant Depression NCT05813093NA1 site📍 Toronto Sunnybrook Health Sciences Centre · Tests: rTMS Comorbid Obesity and Depression With an Anti-inflammatory Medication NCT06537921NA1 site📍 London King's College London · Tests: Minocycline 200mg Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain Stimulation NCT06542094NA1 site📍 Chengdu West China Hospital · Tests: Deep Brain stimulation NMDA Receptor Antagonist Nitrous Oxide Targets Affective Brain Circuits NCT02994433Phase 11 site📍 St Louis Washington University School of Medicine · Tests: Nitrous Oxide, Placebo gas, MRI Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant Depression NCT06511908Phase 21 site📍 Bethesda National Institute of Mental Health (NIMH) · Tests: (2R,6R)-hydroxynorketamine (0.25 to 2.0 mg/kg), Placebo
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