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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

Know your stage or your test results (such as EGFR, HER2 or BRCA)? Match trials to your own profile - nothing you type is saved.

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30 recruiting trials

for Unresectable

Substudy 06E: Umbrella Study of Combination Therapies in Esophageal Cancer (MK-3475-06E/KEYMAKER-U06) NCT06780111Phase 1, Phase 252 sites📍 Pittsburgh📍 Natal📍 Porto Alegre Merck Sharp & Dohme LLC · Tests: Pembrolizumab, I-DXd, Leucovorin, Levoleucovorin, 5-Fluorouracil (5-FU) Anlotinib + Benmelstobart + HAIC in Unresectable HCC: A Phase II Study NCT07806292Phase 21 site📍 Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Tests: anlotinib combined with benmelstobart and HAIC A Clinical Trial Evaluating TQB2102 for Injection in Combination With Behmosubaisumab/Payamprolizumab With or Without Chemotherapy in Unresectable Locally Advanced, Recurrent, or Metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastroesophageal Adenocarcinoma NCT06767800Phase 239 sites📍 Fuyang📍 Lu'an📍 Maanshan Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Phar… · Tests: TQB2102 for injection (7.5 mg) +Benmelstobart+Chemotherapy, TQB2102 for injection (6 mg/7.5 mg) +Benmelstobart+Chemothe… Intermittent or Continuous Panitumumab Plus FOLFIRI for Left Sided RAS/B-RAF Wild-type Metastatic Colorectal Cancer NCT06509126Phase 31 site📍 Naples National Cancer Institute, Naples · Tests: Panitumumab, Irinotecan, 5-fluorouracil, L-folinic acid Safety and Efficacy of Tremelimumab+Durvalumab(MEDI4736)+TACE in Unresectable Hepatocellular Carcinoma NCT06911255Phase 1, Phase 21 site📍 Seoul Yoon Jun Kim · Tests: Tremelimumab Plus Durvalumab (MEDI4736), Transarterial chemoembolization (TACE) Intratumoral MMR Vaccine Injection in Borderline Resectable/Unresectable Pancreatic Cancer NCT07539155Phase 1, Phase 21 site📍 Little Rock University of Arkansas · Tests: Intratumoral MMR Injection Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, AXIOM Trial NCT05333458Phase 213 sites📍 Los Angeles📍 Los Angeles📍 Los Angeles National Cancer Institute (NCI) · Tests: Atezolizumab, Biopsy Procedure, Biospecimen Collection, Computed Tomography, Echocardiography Test A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement NCT07359820Phase 219 sites📍 Phoenix📍 Jacksonville📍 Tampa Elevar Therapeutics · Tests: Lirafugratinib Brachytherapy (Iodine-125 Seeds) and Fluzoparib Combination Therapy for Advanced Unresectable Soft Tissue Sarcoma NCT05894018Phase 21 site📍 Guangzhou Fujun Zhang · Tests: Fluzoparib, Radioactive particle implantation A Phase II Study of GFH375 Combined With GFS202A or GFH276 Versus GFH375 in Patients With Previously Treated Locally Advanced Unresectable or Metastatic Pancreatic Cancer Harboring KRAS G12D Mutation NCT07784374Phase 21 site📍 Shanghai Genfleet Therapeutics (Shanghai) Inc. · Tests: GFH375, GFH276, GFS202A Enfortumab Vedotin Plus Pembrolizumab for the Treatment of Locally Advanced or Metastatic Bladder Cancer of Variant Histology NCT05756569Phase 24 sites📍 Atlanta📍 Atlanta📍 Atlanta Emory University · Tests: Biospecimen Collection, Computed Tomography, Enfortumab Vedotin, Magnetic Resonance Imaging, Pembrolizumab Clinical Trial of AMG510 in Stage III Unresectable NSCLC KRAS p.G12C Patients and Ineligible for Chemo-radiotherapy NCT05398094Phase 220 sites📍 Alicante📍 Badalona📍 Barcelona Fundación GECP · Tests: Sotorasib Conversion Therapy With RC48, Sintilimab, and SOX for HER2 1+/2+ Unresectable Gastric Cancer NCT07194005Phase 21 site📍 Shanghai Fudan University · Tests: Disitamab vedotin(RC48), Sintilimab, S-1, Oxaliplatin Nimotuzumab Plus Definite Chemoradiotherapy(dCRT) in Elderly Patients With Esophageal Squamous Cell Carcinoma NCT06988956Phase 21 site📍 Nanjing The First Affiliated Hospital with Nanjing Medical Universi… · Tests: Nimotuzumab, Tegafur, radiotherapy Study of the Theranostic Pair RYZ811 (Diagnostic) and RYZ801 (Therapeutic) to Identify and Treat Subjects With GPC3+ (Glypican-3) Unresectable HCC NCT06726161Phase 1, Phase 213 sites📍 Birmingham📍 Phoenix📍 Orange RayzeBio, Inc. · Tests: RYZ811, RYZ801 Testing the Safety and Efficacy of the Combination of Two Anti-cancer Drugs, ZEN003694 and Abemaciclib, for Adult and Pediatric Patients (12-17 Years) With Metastatic or Unresectable NUT Carcinoma, Breast Cancer and Other Solid Tumors NCT05372640Phase 17 sites📍 Los Angeles📍 Los Angeles📍 Los Angeles National Cancer Institute (NCI) · Tests: Abemaciclib, BET Bromodomain Inhibitor ZEN-3694, Biopsy Procedure, Biospecimen Collection, Diagnostic Imaging Testing A Prospective Phase II Clinical Study of Immunotherapy Combined With Chemotherapy for Stage III Unresectable Non-small Cell Lung Cancer NCT07082179Phase 21 site📍 Nanjing Jiangsu Cancer Institute & Hospital · Tests: Iparomlimab and Tuvonralimab combined with paclitaxel polymer micelles and Platinum (cisplatin/carboplatin) Ablative Carbon Ion Radiotherapy With Pencil Beam Scanning for Locally Advanced Unresectable Pancreatic Cancer NCT05424159NA1 site📍 Shanghai Shanghai Proton and Heavy Ion Center · Tests: Carbon ion radiotherapy Phase 1 Clinical Trial of Lenvatinib, Pembrolizumab and Hypofractionated Pelvic Radiation Therapy for pMMR Recurrent/Unresectable Endometrial Carcinoma NCT05603910Phase 11 site📍 Miami Aaron Wolfson · Tests: Lenvatinib, Pembrolizumab, Hypofractionated External Beam Radiation Therapy, High-Dose Rate (HDR) Brachytherapy Vorolanib in the Second-line Treatment of Patients With Unresectable or Metastatic Renal Cell Carcinoma NCT06676527n/a1 site📍 Nanjing Jinling Hospital, China · Tests: Follow-up study of the treated cohort LIver TrAnspLantation for Non-resectable Peri-HIlar cholangioCArcinoma (LITALHICA) NCT06125769NA1 site📍 Padova Azienda Sanitaria Ospedaliera · Tests: Liver transplantation A Trial of Apatinib and Adebrelimab in Combination With Chemotherapy in Patients With Unresectable ICC NCT06925516Phase 21 site📍 Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Tests: Apatinib and Adebrelimab in Combination With chemotherapy Hepatic Arterial Infusion of Gemcitabine-oxaliplatin for Second-line Therapy in Non-metastatic Unresectable Intra-hepatic Cholangiocarcinoma NCT03364530Phase 27 sites📍 Amiens📍 Angers📍 Bordeaux University Hospital, Montpellier · Tests: Gemcitabine-Oxaliplatin Regimen, Hepatic intra arterial chemotherapy Fecal Microbiota Transplantation to RESCUE Patients With Unresectable Hcc Progressors to First Line Therapy With AtezolizUmaB and Bevacizumab NCT07276100Phase 21 site📍 Bologna IRCCS Azienda Ospedaliero-Universitaria di Bologna · Tests: Fecal microbiota transplantation (FMT), Atezolizumab & Bevacizumab A Study to Observe the Safety of VYLOY (Zolbetuximab) in People in South Korea With Gastric or Gastroesophageal Junction Cancer. NCT06902545n/a15 sites📍 Goyang-si📍 Suwon📍 Suwon Astellas Pharma Korea, Inc. · Tests: zolbetuximab SIRT Versus cTACE for Unresectable HCC (CHANCE2506) NCT06909708NA1 site📍 Nanjing Zhongda Hospital · Tests: SIRT, cTACE RGL-270 + ICI in Advanced NSCLC NCT07652125NA1 site📍 Guangzhou Guangdong Association of Clinical Trials · Tests: RGL-270 in Combination with PD-1/PD-L1 Inhibitors, Physician's Choice SOC Atezolizumab and Bevacizumab With Photon Radiotherapy for Unresectable Hepatocellular Carcinoma NCT06339424Phase 21 site📍 Taoyuan City Chang Gung Memorial Hospital · Tests: Atezolizumab, Bevacizumab, Photon radiotherapy Study of Antitumor Immune Response After cCRT and IO Treatment in Non-resectable III Stage NSCLC Patients NCT06634199n/a22 sites📍 Ferrol📍 Alicante📍 Badalona Fundación GECP · Tests: Durvalumab The COMPASSION Study NCT06507930NA1 site📍 Boston Dana-Farber Cancer Institute · Tests: Telehealth Hospice Visits
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