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Trial Match

Clinical trials test new treatments — sometimes the newest options available for a disease. Find trials that are recruiting now, near you. Open one to see its eligibility rules as simple questions to go through with your doctor.

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30 recruiting trials

for Unresectable Cholangiocarcinoma

A Study of Lirafugratinib in Non-CCA Solid Tumors With FGFR2 Fusion or Rearrangement NCT07359820Phase 219 sites📍 Phoenix📍 Jacksonville📍 Tampa Elevar Therapeutics · Tests: Lirafugratinib LIver TrAnspLantation for Non-resectable Peri-HIlar cholangioCArcinoma (LITALHICA) NCT06125769NA1 site📍 Padova Azienda Sanitaria Ospedaliera · Tests: Liver transplantation A Trial of Apatinib and Adebrelimab in Combination With Chemotherapy in Patients With Unresectable ICC NCT06925516Phase 21 site📍 Guangzhou Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Tests: Apatinib and Adebrelimab in Combination With chemotherapy Hepatic Arterial Infusion of Gemcitabine-oxaliplatin for Second-line Therapy in Non-metastatic Unresectable Intra-hepatic Cholangiocarcinoma NCT03364530Phase 27 sites📍 Amiens📍 Angers📍 Bordeaux University Hospital, Montpellier · Tests: Gemcitabine-Oxaliplatin Regimen, Hepatic intra arterial chemotherapy Modified Immune Cells (Autologous Dendritic Cells) and a Vaccine (Prevnar) Combined With Immune Checkpoint Inhibition After High-Dose External Beam Radiation Therapy in Treating Patients With Unresectable Liver Cancer NCT03942328Phase 1, Phase 21 site📍 Rochester Mayo Clinic · Tests: Atezolizumab, Bevacizumab, External Beam Radiation Therapy, Pheresis, Pneumococcal 13-valent Conjugate Vaccine Liver Transplantation for Non-Resectable Intrahepatic Cholangiocarcinoma: a Prospective Exploratory Trial (TESLA Trial) NCT04556214NA1 site📍 Oslo Oslo University Hospital · Tests: Liver Transplant Liver Transplantation for Non-resectable Perihilar Cholangiocarcinoma NCT04993131NA1 site📍 Oslo Oslo University Hospital · Tests: Liver transplant A Study of ICP-192 in Patients With FGFR2-Rearranged Unresectable or Metastatic Intrahepatic Cholangiocarcinoma NCT05678270Phase 244 sites📍 Hefei📍 Beijing📍 Beijing Beijing InnoCare Pharma Tech Co., Ltd. · Tests: ICP-192 Dual-Target HER2/CEA CAR-NK Cells in Advanced Biliary Tract Cancer NCT07641036Phase 1, Phase 21 site📍 Shenzhen Beijing Biotech · Tests: EB-HC01 dual-target CARNK cells, Fludarabine, Cyclophosphamide D-TACE-HAIC Combined With Envafolimab and Lenvatinib for Unresectable ICC NCT06643208n/a1 site📍 Fuzhou Fujian Provincial Hospital · Tests: TACE-HAIC, Envafolimab and Lenvatinib Toripalimab Plus Lenvatinib and Gemcitabine-based Chemotherapy in 1L Treatment of Advanced ICC: a Phase III Study NCT05342194Phase 31 site📍 Shanghai Shanghai Junshi Bioscience Co., Ltd. · Tests: Toripalimab, Lenvatinib mesylate capsules, Placebo IV, Oral placebo, Oxaliplatin for injection Endoscopic Radiofrequency Ablation for Unresectable Cholangiocarcinoma NCT06175845NA9 sites📍 Berlin📍 Bonn📍 Chemnitz Universitätsklinikum Hamburg-Eppendorf · Tests: Intraductal biliary radiofrequency ablation Repeated Endobiliary Radiofrequency Ablation Plus Durvalumab, Gemcitabine, and Cisplatin for Unresectable Extrahepatic Cholangiocarcinoma NCT07235007NA8 sites📍 Aichi📍 Aichi📍 Aichi Aichi Medical University · Tests: Endobiliary Radiofrequency Ablation (EB-RFA), Plastic Biliary Stent Liver Transplantation for Unresectable Intrahepatic Colangiocarcinoma After Sustained Response to Neoadjuvant Treatments NCT06862934n/a1 site📍 Milan Fondazione IRCCS Istituto Nazionale dei Tumori, Milano A Study of ASP546C in Adults With Gastroesophageal Cancer, Pancreatic Cancer or Other Solid Tumors NCT07488676Phase 1, Phase 221 sites📍 Birmingham📍 Los Angeles📍 Miami Astellas Pharma Global Development, Inc. · Tests: ASP546C Y-90 With Durvalumab/Gem/Cis in Intrahepatic Cholangio NCT05655949Phase 21 site📍 Boston Beth Israel Deaconess Medical Center · Tests: Gemcitabine, Cisplatin, Durvalumab, Yttrium-90 Phase II Clinical Study of GemOX Hepatic Arterial Infusion Combined with Lenvatinib and Toripalimab for Advanced and Unresectable Intrahepatic Cholangiocarcinoma and Gallbladder Cancer NCT06852287Phase 21 site📍 Tianjin Tianjin Medical University Cancer Institute and Hospital · Tests: chemotherapy with gemcitabine and oxaliplatin; small molecure TKI lenvatinib; immune-checkpoint inhibitor toripalimab. Stereotactic Body Radiation Therapy After Chemotherapy for Unresectable Perihilar Cholangiocarcinoma NCT06493734NA8 sites📍 Wilrijk📍 Brussels📍 Nijmegen Erasmus Medical Center · Tests: Stereotactic body radiation therapy Precision Medicine in Patients With Unresectable CholAngiocarcinoma: RadioEmbolization and Combined Biological Therapy NCT06375915Phase 24 sites📍 Bergamo📍 Milan📍 Naples Francesco De Cobelli · Tests: radioembolization with Y-90, Durvalumab, Cisplatin, Gemcitabine PDS01ADC in Combination With Hepatic Artery Infusion Pump (HAIP) and Systemic Therapy for Subjects With Metastatic Colorectal Cancer, Intrahepatic Cholangiocarcinoma, or Metastatic Adrenocortical Carcinoma NCT05286814Phase 21 site📍 Bethesda National Cancer Institute (NCI) · Tests: Dexamethasone, PDS01ADC, Intera 3000 Hepatic Artery Infusion Pump (HAIP), Floxuridine Alternating Chemo-immunotherapy and FGFR Inhibitor for FGFR-positive Biliary or Cholangiocarcinoma NCT07780838Phase 21 site📍 Columbus Ohio State University Comprehensive Cancer Center · Tests: Biospecimen Collection, Cisplatin, Computed Tomography, Durvalumab, Gemcitabine Phase II Study of Neoadjuvant Tislelizumab Plus Radiotherapy and GP Chemotherapy for Borderline/Unresectable Hilar Cholangiocarcinoma NCT07030140Phase 21 site📍 Jinan Jinbo Yue · Tests: Stereotactic Body Radiotherapy (SBRT), Tislelizumab, Gemcitabine, Cisplatin or Oxaliplatin Liver Transplantation for Unresectable Perihilar Cholangiocarcinoma NCT06986486n/a1 site📍 Milan Fondazione IRCCS Istituto Nazionale dei Tumori, Milano HAIC Plus QL1706 & Bevacizumab in Unresectable HER2-Negative ICC NCT07841574Phase 21 site📍 Guangzhou Lianghe Lu · Tests: hepatic arterial infusion chemotherapy (HAIC) combine with QL1706 and bevacizumab Liver Transplant Combined With Neoadjuvant Chemo-radiotherapy in the Treatment of Unresectable Perihilar Cholangiocarcinoma. A Prospective Multicenter Study. NCT04378023n/a1 site📍 Barcelona Hospital Vall d'Hebron · Tests: Neoadjuvant Chemo-radiotherapy, Liver Transplantation Radioembolization With Tremelimumab and Durvalumab for Locally Advanced Unresectable or Oligo-Metastatic Intrahepatic Cholangiocarcinoma NCT06058663Phase 11 site📍 Jacksonville Mayo Clinic · Tests: Angiography, Biopsy, Biospecimen Collection, Computed Tomography, Durvalumab Gemcitabine and Oxaliplatin Chemotherapy With or Without a Floxuridine and Dexamethasone Pump in People With Cholangiocarcinoma That Cannot Be Removed With Surgery NCT04891289Phase 211 sites📍 Bethesda📍 St Louis📍 Basking Ridge Memorial Sloan Kettering Cancer Center · Tests: Gemcitabine, Oxaliplatin, Dexamethasone, Floxuridine (FUDR), Implanted Medical Device CT-95 in Advanced Cancers Associated With Mesothelin Expression NCT06756035Phase 19 sites📍 Denver📍 Chicago📍 Grand Rapids Context Therapeutics Inc. · Tests: CT-95 The Purpose of This Research Study is to See if Combining Gemcitabine, Cisplatin and Durvalumab Chemotherapy Treatments With a Direct Tumor Therapy Yittrium-90 (Y-90) Will Work Better Together to Shrink Tumors and Control Cancer NCT05422690Phase 21 site📍 Fairfax Inova Health Care Services · Tests: Induction Chemotherapy Triplet Therapy, Concurrent Y-90 treatment, Consolidation Doublet Therapy: A Study of Rilvegostomig or Durvalumab Plus Chemotherapy for First-Line Treatment of Biliary Tract Cancer (ARTEMIDE-Biliary02) NCT07221253Phase 3183 sites📍 Birmingham📍 Phoenix📍 Tucson AstraZeneca · Tests: Rilvegostomig, Durvalumab, Gemcitabine/Cisplatin
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